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IL-17 inhibitors - Long-term Extensions and Uveitis Dr. Peter Nash offers his perspective on data presented at the 2025 EULAR meeting in Barcelona. https://t.co/eQd0TcQn76 https://t.co/6Zog4LC8Aj
Dr. John Cush @RheumNow ( View Tweet )
6 months 3 weeks ago
FDA adds new warning for "myocarditis" to the Pfizer and Moderna COVID-19 vaccines (prev mainly assoc w/ Moderna) - risk is 8 per 1 million people for those on 2023-2024 COVID shots, most common in males ages 12 to 24. Generally good outcomes seen. https://t.co/QZbTRaKGH1 https://t.co/1cAUw73eqF
Dr. John Cush @RheumNow ( View Tweet )
6 months 3 weeks ago
Jekyll and Hyde: which RA-ILD is it? Dr. David Liew reports on abstract OP0329 presented at the EULAR 2025 meeting in Barcelona, Spain. https://t.co/oH9nXaKRDz https://t.co/iUAJk2Q856
Dr. John Cush @RheumNow ( View Tweet )
6 months 3 weeks ago
Prospective KORAIL study of 138 RA pts w/ ILD on chest CT -60% had UIP ILD. After F/U of 2.9 yrs, 35% had RA-ILD progression. Baseline predictors of progression = UIP, ILD >10 %, DLCO %pred, CCP+, KL-6 levels, RA Dz activity. Useful to ID high-risk RA-ILD pts.

Dr. John Cush @RheumNow ( View Tweet )

6 months 4 weeks ago
Aortic aneurysms w/ GCA. TriNetX study of 7,294 Bx-proven GCA vs 265,948 controls w/ tension HA. GCA had signif higher 5-yr risk of aortic aneurysms (3.59%; aHR 1.98), including thoracic thoracoabdominal & abdominal. Carotid A stenosis also incr in GCA (aHR 1.59) https://t.co/15fwlHa0FG
Dr. John Cush @RheumNow ( View Tweet )
6 months 4 weeks ago
There's an App for That (and it works): the AXIA RCT Dr. Aurelie Najm reports on abstract LB0002 presented at the EULAR 2025 meeting in Barcelona, Spain. https://t.co/IRZ1L7BqLW https://t.co/Av2vVheShE
Dr. John Cush @RheumNow ( View Tweet )
6 months 4 weeks ago
JAMA Clinical Challenge - 34-yoF with Forearm Pain and Stiffness. 1 yr of progressive skin tightening over forearms, tibia, LOM of fingers & elbows. Denied DM, Raynauds. Worse after tennis, better w/ steroids. Increased ANA, eosinophils, CRP, aldolase - your Dx? https://t.co/ppuzIB4iRf
Dr. John Cush @RheumNow ( View Tweet )
6 months 4 weeks ago
What we need in very early arthritis It's easy to think that in our current world that we've done it all for rheumatoid arthritis, that there's nothing left to be done after b/tsDMARDs have become relatively widespread and accessible. If we aren’t satisfied that we’ve done all https://t.co/v8T3JQwuhM
Dr. John Cush @RheumNow ( View Tweet )
6 months 4 weeks ago
Korean Health claims data study of 35,133 newly Dx, seropositive #RA pts (2011 to 2020) & 1,386 (3.9%) were Dx w/ new-onset stroke (CVA). Signif. lower risk of CVA w/ SSZ (aOR: 0.79) or HCQ (aOR: 0.83), but Increased risk w/ glucocorticoids (aOR: 1.71) & tocilizumab (aOR: 3.47) https://t.co/rPaj6cH74K
Dr. John Cush @RheumNow ( View Tweet )
6 months 4 weeks ago
Using Veterans Affairs data (2006 - 2020) on RA-ILD patients, a target emulation trial showed no difference in mortality or respiratory hospitalization comparing RA-ILD Rx w/ either RTX, abatacept, tocilizumab, tofacitinib. Does this mean? they Dont Work or the Do Work? https://t.co/MkQmKsE3WQ
Dr. John Cush @RheumNow ( View Tweet )
6 months 4 weeks ago
What would it take for JAKs to ROCK the boat? JAK inhibitors have taken a beating over the last three years. The excitement and potential has been tempered by mounting cardiovascular safety concerns, but specifically in at-risk patients, compared to TNF inhibitors. https://t.co/tgfsU3uFVo
Dr. John Cush @RheumNow ( View Tweet )
6 months 4 weeks ago
post hoc MRI study from Osteoarthritis Initiative (OAI) of 210 knee OA pts (mean age 64) Rx w/ either IA corticosteroids or hyaluronate (HA). Bboth reduced pain post-injx (WOMAC -5.2 CS & -2.1 HA), CS had worse progression (cartilage, BM lesions, meniscus) vs controls & HA https://t.co/pbb1ePXob1
Dr. John Cush @RheumNow ( View Tweet )
6 months 4 weeks ago
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