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A&R reviews the inflammasome in autoimmune diseases. Pattern recognition recpt induce inflammasome activation, pro-caspase-1 converts to caspase-1 convertin pro-IL-1β and pro-IL-18 active IL-1β and IL-18; seen in RA, SLE, gout, Sjogrens https://t.co/JGadiEWQWf

Dr. John Cush @RheumNow ( View Tweet )

6 years 10 months ago
CDC advises against vaping with marijuana, noting that up to 77% of 805 cases and 12 deaths from lung disease tied to vaping with THC https://t.co/dtDvMJ1dlA

Dr. John Cush @RheumNow ( View Tweet )

6 years 10 months ago
Survey for Rheumatologists - You would use an MRI in an RA to assess what?

Dr. John Cush @RheumNow ( View Tweet )

6 years 10 months ago
5-factor score for mortality in ANCA-associated vasculitis. I’ve never seen a worse Kaplan-Meier survival curve for those with a score of 5! @philseo #CCRwest 😬☠️ https://t.co/utK7avZ0F1
Jeff Sparks @jeffsparks ( View Tweet )
6 years 10 months ago
The RheumNow Podcast is up - discussing PSS & Cancer, SLE & narcotics, AAV & Lipids, Anakinra & NIDDM. Watch it here>> https://t.co/PolTYQqbBW or listen to the podcast on iTunes, or SoundCloud>> https://t.co/ILQQw2kpse

Dr. John Cush @RheumNow ( View Tweet )

6 years 10 months ago
TIF1-γ antibodies may be associated with dermatomyositis and are found in between 13 – 31% of adults and 22 – 29% of children. TIF1-γ antibodies have a strong association with malignancy, esp in patients over the age of 39. https://t.co/0o2VfNwbZC

Dr. John Cush @RheumNow ( View Tweet )

6 years 10 months ago
Dr. Rob Speira & HSS investigators will lead a multicenter, phase II, 6 mos clinical trial of anti-GM-CSF (mavrilimumab) in patients with giant cell arteritis (GCA. There is still heavy reliance on steroids in GCA; tocilizumab was FDA approved in in 2017 https://t.co/zDWgSVuXec

Dr. John Cush @RheumNow ( View Tweet )

6 years 10 months ago
Question for Rheumatologists - How do you scoreboard your performance as a Rheumatologist?

Dr. John Cush @RheumNow ( View Tweet )

6 years 10 months ago
41 participants with RA and T2D were randomised to recv anakinra or a TNFi; RA dz activity decreased in both groups over 6 mos. Anakinra significantly improved A1C at 3 and 6 mos, but TNFi did not. https://t.co/UIBsRjMbKR

Dr. John Cush @RheumNow ( View Tweet )

6 years 10 months ago
JAMA study shows inconsistencies and inaccuracies in EMR documentation of ROS and PE findings compared to observer audible recorded observations - study of 9 ED Residents, 30 pt encounters each, total of 180 ED patients. https://t.co/PttGYvgCue

Dr. John Cush @RheumNow ( View Tweet )

6 years 10 months ago
Question for Rheumatologists - How do you scoreboard your performance as a Rheumatologist?

Dr. John Cush @RheumNow ( View Tweet )

6 years 10 months ago
Systemic sclerosis is associated with an increased cancer risk. A cohort of 1727 SSc pts showed an increased cancer SIR of 2.15 (CI 1.84‐2.49). Most common cancers were breast, melanoma, hematological & lung. CA risk higher w/ RNAP III Ab, CCB Rx & ILD https://t.co/q5iTRI91Ng

Dr. John Cush @RheumNow ( View Tweet )

6 years 10 months ago
FDA issues warning against the use of higher doses of Imodium (loperamide) - has been associated with "serious heart problems and deaths with much higher than the recommended doses of loperamide". https://t.co/UxPn6F6BL0

Dr. John Cush @RheumNow ( View Tweet )

6 years 10 months ago
Altoona Arthritis Center and Dr. Alan Kivitz praised in the news for their unique blend of patient care and clinical trials research https://t.co/9kGLBhwzsn

Dr. John Cush @RheumNow ( View Tweet )

6 years 10 months ago
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