Tweets
Swedish registry comparison of 541 PsA 40944 non-PsA pregnancies between 1997-2014, shows PsA pregnancies had increased risks for preterm birth (adj OR 1.63) and caesarean deliveries (OR 1.47), but no increased risks for pre-eclampsia, stillbirth https://t.co/L5GcNVbjgQ
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Dr. John Cush @RheumNow ( View Tweet )
7 years 1 month ago
Analysis of 14 studies &3291 Psoriatic arthritis patients shows the overall frequency of anti-CCP antibodies=9.8%. In PsA, CCP+ was associated with increased risks of polyarthritis (OR 4.4), bone erosion (2.8), and dactylitis (1.98), but not of enthesitis. https://t.co/hM11ZaskfV
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Dr. John Cush @RheumNow ( View Tweet )
7 years 1 month ago
Study of 182 hospitalized adult-onset Still's disease patients shows predictive factors for developing macrophage activation syndrome to include: 1. Splenomegaly (OR 5.745), 2. pericarditis (OR 6.5), and 3. ferritin >2000 (OR 4.7). https://t.co/oNsaCL6O92
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Dr. John Cush @RheumNow ( View Tweet )
7 years 1 month ago
Increased time spent in lupus low dz activity state (LLDAS) reduces healthcare costs. Among 212 SLE pts analyzed; increased cost assoc w/ damage & steroid use, but spending ≥50% of time in LLDAS resulted in a 26% reduction in direct medical cost https://t.co/Kfd064kZFX
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Dr. John Cush @RheumNow ( View Tweet )
7 years 1 month ago
Study of 28 states and 10.268 lupus Medicaid patients showed that only 15% were adherent to Plaquenil treatment. Adherence was lower in blacks living in certain zip codes but not in zip codes prevalents for Hispanic, white, education, poverty level. https://t.co/ytFXaOGKB2
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Dr. John Cush @RheumNow ( View Tweet )
7 years 1 month ago
CBD isn't entirely safe. Forbes reviews evidence of hepatotoxicity, esp with the CBD-based epilepsy drug Epidiolex; in studies 5-20% had liver issues. FDA has also warned of suicidal ideation, agitation, suicide, depression, aggression & panic attacks https://t.co/I83QVXwsl6
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Dr. John Cush @RheumNow ( View Tweet )
7 years 1 month ago
Metanalysis of 277 RCTs &1 million evaluated 16 nutritional supplements & 8 dietary interventions showed largely no effect on mortality and CV outcomes in adults. There was evidence favoring reduced salt & omega-3, long-chain fatty acids. https://t.co/sojx842jLt
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Dr. John Cush @RheumNow ( View Tweet )
7 years 1 month ago
Judge rules that the Trump administration does not have the legal authority to Force Drugmakers To Include Prices In Ads https://t.co/zsJfg5xp4J
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Dr. John Cush @RheumNow ( View Tweet )
7 years 1 month ago
RTX product label lists Serum Sickness (SS) as uncommon postmarketing AE. Study of 37 pts w/ RTX SS finds that 3/4 occurred in SLE & autoimmune dz; 1st inf54% during 1st injxn, usually w/in 12 days. Manifest as MSK sx (92%), fever (87%), skin lesions(78%) https://t.co/gc8CUXhqxL
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Dr. John Cush @RheumNow ( View Tweet )
7 years 1 month ago
RTX product label list these postmarketing AEs (not seen in trials) - uveitis, optic neuritis, systemic vasculitis, pleuritis, lupus-like syndrome, serum sickness, polyarticular arthritis, and vasculitis with rash. https://t.co/kpr699j2wQ
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Dr. John Cush @RheumNow ( View Tweet )
7 years 1 month ago
Metanalysis shows the prevalence of autoimmune hepatitis for Asian, European, and American populations was 12.99 (95% CI: 2.05–23.92), 19.44 (15.63–23.24), and 22.80 (13.48 to 59.07) per 100,000; higher rates seen in women and elderly https://t.co/OtvvWBvb3x
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Dr. John Cush @RheumNow ( View Tweet )
7 years 1 month ago
A nested case-control study of 120 SLE pts matched against 240 controls and showed the risk of serious infections was associated with serositis (OR 2.76), hematologic involvement (OR 2.53) and daily steroid (>7.5mg/d) use (OR, 2.53). https://t.co/5zqV9jsNq1
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Dr. John Cush @RheumNow ( View Tweet )
7 years 1 month ago
Survey of 1000 customers of two adult-use cannabis retail stores in Colorado shows that 65% of adults use cannabis to relieve pain & 74% use it to promote sleep. Over 80% said that cannabis was very or extremely helpful for pain or sleep. https://t.co/euDm7yq7Rc
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Dr. John Cush @RheumNow ( View Tweet )
7 years 1 month ago
Dr. Kevin Winthrop at #EULAR2019 during his infection lecture delivers the Pearl that Tofacitinib pts found to have Latent TB cannot take Rifampin - drug interaction w/ Tofa (lowers levels) https://t.co/LpoRbVC77J
Dr. John Cush @RheumNow ( View Tweet )
7 years 1 month ago
Dr. Kevin Winthrop - Expert Advice on TB Testing and Treatment from #EULAR2019 https://t.co/Nz7oKiIjrm
Dr. John Cush @RheumNow ( View Tweet )
7 years 1 month ago
