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RheumNow Podcast is UP! Discussions of MTX stomatitis, Loading doses, PPD Shortage, infection risk from steroids or THR/TKR and more. Watch it here>> https://t.co/8koj2HG4RC or listen in on iTunes or SoundCloud >> https://t.co/0EXaXq2l7G
Dr. John Cush @RheumNow ( View Tweet )
7 years 1 month ago
FDA has announced that on July 25th it will hold an Arthritis Advisory Committee Meeting to discuss Boehringer Ingelheims application for Nintedanib use in systemic sclerosis-associated interstitial lung disease (SSc-ILD) https://t.co/z4uLJ8hdyX
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Dr. John Cush @RheumNow ( View Tweet )
7 years 1 month ago
What’s next in biosimilars? Visit RheumNow to listen to experts discuss this and more in "Therapeutic Update: Biosimilars in Rheumatology," a video series sponsored by Sandoz, Inc. https://t.co/1vmnEJqOSi #sponsored
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Dr. John Cush @RheumNow ( View Tweet )
7 years 1 month ago
Metanalysis of 3954 studies, 20 RCTs examined MTX toxicity and found the prevalence of alopecia to be 1- 4.9% and the prevalence of stomatitis to be between 5.7-8% https://t.co/LHbAYvV71X
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Dr. John Cush @RheumNow ( View Tweet )
7 years 1 month ago
A Western Norway study of GCA (1972–2012) compared 792 GCA (528 Bx-verified) to 2577 matched controls. There were no differences in overall survival (p=0.41). GCA had higher risk of CV death (HR 1.31) but lower risk of cancer deaths (HR 0.56). https://t.co/oBx2kBTyrZ
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Dr. John Cush @RheumNow ( View Tweet )
7 years 1 month ago
The BMS merger with Celgene to be hastened by BMS divesting itself from Otezla. https://t.co/Ew0sg9YSaZ
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Dr. John Cush @RheumNow ( View Tweet )
7 years 1 month ago
ORAL Strategy, 216 or 18.8% received the Zostvax vaccine. Overall, 18 patients (1.6%) developed HZ (vaccinated=3; non-vaccinated=15). HZ IRs (95% CI) were 1.1 (0.3, 2.9), 2.3 (1.0, 4.6), and 1.7 (0.6, 3.7) for tofa monotherapy, tofa+MTX, & ADA+MTX, resp. https://t.co/SE5ANjRHB8
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Dr. John Cush @RheumNow ( View Tweet )
7 years 1 month ago
795 RA patients from the GIRRCS cohort 3 year study found that maintaining remission reduced the incidence of subclinical atherosclerosis by three-quarters (OR = 0.25; P = .001). (87% were on MTX; 60% on biologics) #EULAR2019 ABST# OP0090 https://t.co/RvRcXsDnKs
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Dr. John Cush @RheumNow ( View Tweet )
7 years 1 month ago
Study of 1224 SLE pts found 7% with neuropathies (PNS) w/ 2/3 attributable to SLE. 67% PNS occurred w/in 3 mos of SLE diagnosis. Periph. polyneuropathy was most common (43%). PNS pts were older, w/ higher SLEDAI-2K, Sjogrens, livedo, HTN, DM. https://t.co/G7l2GGbmgR
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Dr. John Cush @RheumNow ( View Tweet )
7 years 1 month ago
2,899 RA and 112,571 OA pts had THA or TKA. RA had more infections (HR 1.29;1.03-1.61) post THA/TKA, but fewer VTE (HR 0.60; 0.26-0.98) post TKA. Biologics in RA had a similar infx risk but more VTE (HR 4.82;1.67-13.9) vs non-biologics. https://t.co/Lv1QLbjZjx
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Dr. John Cush @RheumNow ( View Tweet )
7 years 1 month ago
137 consecutive RA pts were evaluated by electronic stethoscopy of 4 lung fields to identify "VELCRO" lung sounds as an indicator of early ILD by HRCT. Sensitivity =93.2% and specificity=76.9%, Dx accuracy =83.9%. correctly classified 115/137 pts. https://t.co/0HWYLvgmTL
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Dr. John Cush @RheumNow ( View Tweet )
7 years 1 month ago
"Therapeutic Update: Biosimilars in Rheumatology" video series features nine experts talking about biosimilars, sponsored by Sandoz, Inc. Visit RheumNow to watch: https://t.co/1vmnEJqOSi #sponsored #biosimilars
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Dr. John Cush @RheumNow ( View Tweet )
7 years 1 month ago
After reviewing the safety data, the FDA has removed the risk ofosteoporosis and fracture from the drug facts listing for OTC proton pump inhibitor (PPI) medications https://t.co/RnjtTl2oVV
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Dr. John Cush @RheumNow ( View Tweet )
7 years 1 month ago
Study of PsA (N = 341) pts starting secukinumab with or without a baseline loading dose of SEC 150 mg, showed equal ACR20 responses at week 16 - 41.2% vs 39.8%. Despite some w/ an earlier response, the SEC loading dose may not be necessary. https://t.co/d3z9AQoeGM
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Dr. John Cush @RheumNow ( View Tweet )
7 years 1 month ago
The RheumNow Podcast is up! This time its a Late Breaking Abstract Wrap-Up. Watch it here>> https://t.co/ZoVE5gSdG9 or Podcast listen on iTunes, in your car on Apple Car play or on SoundCloud here>> https://t.co/6AwVH1Zjoy
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Dr. John Cush @RheumNow ( View Tweet )
7 years 1 month ago
