Tweets
Cohort study finds 6/420 (1.4%) of SLE patients had steroid induced pancreatitis is - half of them died. Lit review finds 451 lupus pancreatitis with majority developing pancreatitis w/in 3 days of medium-to-high dose steroids (mortality = 37.5%). https://t.co/QsIHsl44qx
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Dr. John Cush @RheumNow ( View Tweet )
7 years 3 months ago
“..the only difference between those who have failed and those who have succeeded lies in the difference of their habits —I will form good habits and become their slave. - from The greatest Salesman in the World
Dr. John Cush @RheumNow ( View Tweet )
7 years 3 months ago
Eight Survival skills (cont) 5) Set a daily goal and track your progress. 6) find a daily "hassle" & reframe it in a more positive light. 7) Do something nice for someone else each day. 8) Practice mindfulness by paying attention to the present moment https://t.co/8uX7Db7QdB
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Dr. John Cush @RheumNow ( View Tweet )
7 years 3 months ago
Eight Survival skills (from NPR article) to manage stress: 1) identify one positive event each day.2) Tell someone or share that positive event. 3) Start a daily gratitude journal. 4) Whats your personal strength and how have you used it; https://t.co/8uX7Db7QdB
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Dr. John Cush @RheumNow ( View Tweet )
7 years 3 months ago
Study of 281 Italian pts with temporal artery Bx-proven Giant cell arteritis shows increased mortality w/ large vessel involvement (HR 5.14) at diagnosis, and reduced mortality with PMR onset (HR 0.57) & adventitial inflammation (HR 0.31) on TABx. https://t.co/iF90cqYtqn
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Dr. John Cush @RheumNow ( View Tweet )
7 years 3 months ago
Recent Methotrexate use lowers Cardivascular risk by 20% finds a Study of 23,994 elderly RA patients. 13.7% had a CVE (28.5 events per 1000 PY; 95% CI 27.6–29.5). https://t.co/yyR5DUTfF8
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Dr. John Cush @RheumNow ( View Tweet )
7 years 3 months ago
Cush offers drug 'safety rules to live by' for rheumatologists https://t.co/5BKBKZjyNw
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Dr. John Cush @RheumNow ( View Tweet )
7 years 3 months ago
Invincibility lies in the defence; the possibility of victory in the attack. Sun Tzu
https://t.co/jhW2LXrEYv
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Dr. John Cush @RheumNow ( View Tweet )
7 years 3 months ago
2019 FDA Drug Safety Warnings all pertain to Rheumatology agents 1) boxed warning for sleep meds; 2) harms w/ sudden opioid stops; 3) risk of VTE with high dose tofacitinib; 4) cardiac risks with febuxostat https://t.co/yHYqWJ7pow
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Dr. John Cush @RheumNow ( View Tweet )
7 years 3 months ago
Analysis of new drug registration trials in RA (1998-2018) shows an increase in placebo responses (significant for ACR50 & ACR70); yet with significant reductions in Disease duration, SJCand DAS28-ESR. Changes in RA? RCTs? expectation bias? https://t.co/at6uesuNvL
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Dr. John Cush @RheumNow ( View Tweet )
7 years 3 months ago
DESIRABLE study from JAPAN Rx 654 (relatively) early, MTX tx RA pts with PBO, or Prolia given q3 or q6 mos. Denosumab lead to significant reductions in Erosion scores, total Xray (not JSN) and increased BMD (vs PBO); no effect on ACR20/50/70. https://t.co/DQrmXYrhAf
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Dr. John Cush @RheumNow ( View Tweet )
7 years 3 months ago
Osteoarticular involvement with sarcoidosis is uncommon (<13%); in the hands shows a honeycomb/latticework trabecular pattern in metacarpals https://t.co/bE4VgWaEzN
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Dr. John Cush @RheumNow ( View Tweet )
7 years 3 months ago
French real-world study of Psoriatic arthritis pts starting apremilast (n 3207) or MTX (n 2736), finds higher discontinuation rates at 1 yr for apremilast (69%) vs MTX (59%) https://t.co/bhPwaPhX23
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Dr. John Cush @RheumNow ( View Tweet )
7 years 3 months ago
Study of 213 RApatients starting MTX. After mean F/U 4.3 yrs and 6288 ALT tests, 7% had ALT elevation; 21% of these were ALT>1.5×ULN. Strongest predictor was a pre‐treatment elevation of ALT (OR 6). 3% permanently stopped MTX due to ALT elevation. https://t.co/ti4ClypXgQ
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Dr. John Cush @RheumNow ( View Tweet )
7 years 3 months ago
Study of 14928 Autoimmune/Rheum Dz pts in UK Clinical Practice Research database found the influenza vaccination was not associated with arthritis flare or increase in PCP visits (actually lowered consultas for joint pain in following 90 days) https://t.co/rrwu68g7DM
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Dr. John Cush @RheumNow ( View Tweet )
7 years 3 months ago
