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Complacency - not knowing whether you’re in a groove or rut - Lisa Bodell

Dr. John Cush @RheumNow ( View Tweet )

7 years 5 months ago
“Innovation is the pirate ship that sails into the yacht club”. - Lisa Bodell

Dr. John Cush @RheumNow ( View Tweet )

7 years 5 months ago
Shoulder replacement surgery - low risk of revision in older women (2.7%), highest (23%) in men 55-59 yrs; Revision highest in the 1st 5 yrs. SAE risk <90d was <4.8%; highest in men >85 yrs (21%). Pulm embolism risk Rel Risk = 61fold in women 50-64. https://t.co/NVSzfgZvwS

Dr. John Cush @RheumNow ( View Tweet )

7 years 5 months ago
Systematic review of Paternal DMARD exposure prior to pregnancy shows no firm evidence of harm with TNFi, ABA, RTX, azathioprine, cyclosporine, HCQ, leflunomide, MTX or mycophenolate mofetil. Data from 84 papers, 611 male exposures, 5986 pregnancies https://t.co/yfIYoMqaRs

Dr. John Cush @RheumNow ( View Tweet )

7 years 5 months ago
Study of 6529 Afib pts on warfarin, 37.5% were also on aspirin. Adding aspirin to warfarin yielded significantly more bleeding (26 vs 20%), major bleeding (5.7 vs 3.3%), ER visits (13.3 vs 9.8%) but similar thrombosis rates (2.3 vs 2.7%) at 1 yr. https://t.co/m5XDBEN6jh

Dr. John Cush @RheumNow ( View Tweet )

7 years 5 months ago
Claims analysis from Natl Taiwan Health Database, compared 262 JIA pts w/ controls & showed JIA pts have 30 fold higher risk of an adult autoimmune dz- Hazard Ratio=129.5 for RA; aHR-10.1 SLE, 49.62 AS & 8.2 PsA. Highest risk (46x) for JIA onset 11-15 yrs https://t.co/oL3stNLYvc

Dr. John Cush @RheumNow ( View Tweet )

7 years 5 months ago
Risk of pancreatitis with azathioprine in adults estimated to be 3-7%, but unknown in kids. 3374 pairs of pediatric IBD pts compared pts on AZA vs not. AZA use was associated with a 5.82 events/100PY risk of pancreatitis (AZA 49·1 vs NOT 8·4 events/100PY) https://t.co/arap2ShTPN

Dr. John Cush @RheumNow ( View Tweet )

7 years 5 months ago
Rule of thumb on VTE risks: Normal population 0-.4/100PYs; RA patients are increased at 0.3-0.7/100 PY. If a new RA drug were to cause VTE (venous thromboembolic events; DVT/PE) it would have to have a rate consistently higher than 0.5 and probably higher than 0.7/100PY

Dr. John Cush @RheumNow ( View Tweet )

7 years 5 months ago
The PARA study shows among 249 pregnancies (2002-2008), breastfeading was less in RA - at 4-6, 12 & 26 wks postpartum 43%, 26% and 9% of the RA breastfed (vs 63%, 46% & 41% in controls). Many patients D/C breastfeeding so they could start medication. https://t.co/ONf1jgFJYL

Dr. John Cush @RheumNow ( View Tweet )

7 years 5 months ago
A study of 2,369 patients with fibromyalgia showed the mean time from initial complaint to diagnosis was 6.42 years. Comorbidity, younger patient, and older physician age were associated with longer time to diagnosis. https://t.co/mHGIR7C4PW

Dr. John Cush @RheumNow ( View Tweet )

7 years 5 months ago
QD Clinic - Five Leflunomide Pearls | from RheumNow https://t.co/A4dwd0eTQ9

Dr. John Cush @RheumNow ( View Tweet )

7 years 5 months ago
Very 1st case I heard on Rheum Rounds 1984 was on Moya-Moya. A review of Delay & mis-Dx in 38% of 192 pts - time to Dx=mean 5.28 yrs; usually misDx as cerebral vasculitis (31%), stroke(30%) & MS(3.6%). Moyamoya is progressive, occlusive cerebrovascular Dz https://t.co/cxu7s3snEJ

Dr. John Cush @RheumNow ( View Tweet )

7 years 5 months ago
Pt with a history of gout. Acute onset of pain at 1st MTP joint. Ultrasound shows 1st MTP Synovitis. Synovial thickening with hypervascularity is noted on the dorsal aspect of 1st metatarsophalangeal joint. https://t.co/BH4C56Yerq

Dr. John Cush @RheumNow ( View Tweet )

7 years 5 months ago
From CreakyJoints- 20 Things pts wish their Rheums Knew: 1 Fix the Vocab, 2 Dont rush me, 3 Dont sugarcoat, 4 Realistic diet, 5 Listen to me, 6 Dont judge me, 7 Flares last longer than you think, 8 Do a mental check up; AND MORE https://t.co/TuKIn86RNv

Dr. John Cush @RheumNow ( View Tweet )

7 years 5 months ago
Surprising Resignation by FDA Commissioner Scott Gottlieb - cites need for more family. Does so after bring vaping, costs and opioids into the spotlight. Could Rheumatologist Janet Woodcock be the next candidate? https://t.co/FnL7Wn0jnT

Dr. John Cush @RheumNow ( View Tweet )

7 years 5 months ago
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