Tweets
NEJM publishes the CIRT trial - Methotrexate given to stable atherosclerosis patients for nearly 3 years was equal to placebo in the prevention of cardiovascular outcomes (MI, CVA, death, unstable angina). Story covered on RheumNow https://t.co/YCdwzKD9Da
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Dr. John Cush @RheumNow ( View Tweet )
7 years 9 months ago
Connecticuts medical marijuana program has 31 approved medical conditions and just approved medical marijuana for use in intractable headaches, rheumatoid arthritis, degenerative spinal disorders, muscular dystrophy & osteogenesis imperfecta. https://t.co/iuyyWrCQOE
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Dr. John Cush @RheumNow ( View Tweet )
7 years 9 months ago
Physicians and NRA square off in a twitter war regarding CDC reports and ACP position papers on the epidemiology of firearm violence and the need for gun control in the USA. https://t.co/EbwAOLNlvU
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Dr. John Cush @RheumNow ( View Tweet )
7 years 9 months ago
Metanalysis of 10 studies and 204 RA patients suggests that during pregnancy disease activity improved in 60% of patients but flared post-partum in nearly half (47%). https://t.co/DHeY4rgKu1
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Dr. John Cush @RheumNow ( View Tweet )
7 years 9 months ago
The RheumNow Podcast is up - 3 Wiseguy Rheumatologists. Watch it here https://t.co/WudWQPRtXl or listen on iTunes or here https://t.co/OOJ0e2IG0L
Dr. John Cush @RheumNow ( View Tweet )
7 years 9 months ago
Frankincense is derived from Boswellia plants. Boswellia serrata is an Ayurvedic purported to be anti-inflammatory; inhibits 5-lipoxygenase & possibly prostaglandins, Pilot studies in OA have shown significant pain relief and improved physical function https://t.co/OPxal73aIF
Links:
Dr. John Cush @RheumNow ( View Tweet )
7 years 9 months ago
BMJ metanalysis of toxicity w/ checkpoint inhibitors shows risks w/ atezolizumab (hypothyroid, N/V) , pembrolizumab (arthralgia, pneumonitis, hepatic tox), ipilimumab (skin/GI/renal), nivolumab (milder, endocrine); Nivolumab (best safety w/ lung CA) https://t.co/qzcehpLe4S
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Dr. John Cush @RheumNow ( View Tweet )
7 years 9 months ago
What works in Dactylitis? Literature review suggests ustekinumab, ixekizumab, adalimumab, and apremilast are efficient. Secukinumab, clazakizumab, abatacept, and tofacitinib were promising. Brodalumab was ineffective https://t.co/SLPcjBaNAv
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Dr. John Cush @RheumNow ( View Tweet )
7 years 9 months ago
Analysis of Natl Inpatient Sample database (1998-2014) compared outcomes in 87605 SLE pregnancies vs matched cohort: found SLE had more C-section, IU fetal death, Pre-eclampsia, VTE, CKD, HTN, longer stays Presented by Dr. Bella Mehta #ACR18 Abst 1852 https://t.co/iYicIbOlxP
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Dr. John Cush @RheumNow ( View Tweet )
7 years 9 months ago
Durkan Test for CTS is when the Examiner presses the thumbs over carpal tunnel and holds pressure for 30 seconds. The onset of pain or paresthesia in the median nerve distribution within 30 seconds is a positive result . https://t.co/1wlJWzX68H
Dr. John Cush @RheumNow ( View Tweet )
7 years 9 months ago
Do you know who patients perceive to be a "great doctor"? Just listen - its always someone who shows they care and/or someone with a personality. Dispassionate, know-it-all service isnt well received!
Dr. John Cush @RheumNow ( View Tweet )
7 years 9 months ago
Study of 512 pts shows when testing for Carpal Tunnel syndrome Thenar atrophy & sensory loss were highly specific, but thenar atrophy had lowest sensitivity (22%) & Durkan test highest (96%). Tinel had lowest specificity 40.9% and NPV 59.1%. https://t.co/Wi8qxNSxIg
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Dr. John Cush @RheumNow ( View Tweet )
7 years 9 months ago
Korean claims data analysis shows intestinal Behcets disease is associated with a 24-34 fold increased risk of hematologic malignancy (esp leukemia, myelodysplasia) vs population. BD Women not men) have an overall higher cancer risk (SIR 4.27) https://t.co/Ik6KdEGz7u
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Dr. John Cush @RheumNow ( View Tweet )
7 years 9 months ago
N of 1 trial of On-Demand Sildenafil in Raynauds (multiple crossovers in single patient) shows in 38 pts there was a 90% chance of response w/ sildenafil superior to placebo; but substantial heterogeneity of patient responses limits the clinical relevance. https://t.co/FCllFm1FLR
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Dr. John Cush @RheumNow ( View Tweet )
7 years 9 months ago
JAMA Metanalysis shows there is limited evidence showing the benefit of reduced dietary salt intake in heart failure patients. https://t.co/EsxApEUsbe
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Dr. John Cush @RheumNow ( View Tweet )
7 years 9 months ago
