Tweets
Dr. Berent Prakken reviews. IL18 may be a diagnostic biomarker for MAS in systemic JIA (compared to familial or primary HLH)
#pedsinreview #ACR18 @rheumnow
Nicole Bitencourt @NicoleBitencou5 ( View Tweet )
7 years 9 months ago
Use of antiTNF in childhood does NOT appear to increase risk of malignancy in adults according to Medicare claims data, but possibly a malignancy signal seen related to underlying disease. #ACR18 #pedsinreview @rheumnow
Nicole Bitencourt @NicoleBitencou5 ( View Tweet )
7 years 9 months ago
In pts with #dermatomyositis, extracellular vesicles (EVs, released from almost all cells) induce secretion of important pro-inflammatory cytokines. #ExtracellularVesicles are likely important in the #pathogenesis of DM. Abstract1335 Dr. Krisha Desai #ACR18 @RheumNow https://t.co/naMIRuq8JQ
Nicole Bitencourt @NicoleBitencou5 ( View Tweet )
7 years 9 months ago
Lysinuric protein intolerance, a urea cycle disorder, can #mimic #SLE with #lupusnephritis and #MAS. #osteopenia also seen. Need high index of suspicion. #GeneticMimicsOfRheumaticDisease #ACR18 @RheumNow https://t.co/sx2cUPgH73
Nicole Bitencourt @NicoleBitencou5 ( View Tweet )
7 years 9 months ago
#DownsArthritis (often an erosive polyarticular arthritis of small joints) is distict from poly #JIA by analysis of #synovialBx. More CD3+ cells, macrophages, and CD20 cells in joints of kids with Down's arthritis. Abstract2024 Dr. Charlene Foley #ACR18 @RheumNow
Nicole Bitencourt @NicoleBitencou5 ( View Tweet )
7 years 9 months ago
45% of pts with #MAS and 62% of pts with #secondaryHLH carry a heterozygous variant of a gene generally associated with #primaryHLH. Having multiple variants assoc w worse and recurrent MAS or HLH. Abstract 2014 Drs. Passarelli and Bracaglia #ACR18 @RheumNow0 https://t.co/t0AGzQ8c7r
Nicole Bitencourt @NicoleBitencou5 ( View Tweet )
7 years 9 months ago
Among 14 pts with #JIA #ERA (enthesitis related arthritis) who failed 1+ antiTNFs, #secukinumab led to some improvement in the JADAS 10 score at 6 months. The 300 mg dose required in over half of pts. Abstract2386 Dr. Ivan Foeldvari #ACR18 @RheumNow https://t.co/cnVBqreGEG
Nicole Bitencourt @NicoleBitencou5 ( View Tweet )
7 years 9 months ago
Compunded triamcinolone hexacetonide (the steroid formerly know as #Aritospan) showed significantly lower rates of joint flares compared to triamcinolone acetonide in #JIA20% vs 72%. Abstract2387 Dr. April Bingham #considercompunding #ACR18 @RheumNow https://t.co/BMBa4Z2p3t
Nicole Bitencourt @NicoleBitencou5 ( View Tweet )
7 years 9 months ago
Secondary tumoral calcinosis in #SLE. A benign condition characterized by massive periarticular #calcification and associated with CTDs. Image by Dr. Leslie Anne Cassidy #ACR18 @RheumNow https://t.co/gs9YwwFQ3a
Nicole Bitencourt @NicoleBitencou5 ( View Tweet )
7 years 9 months ago
#GPA with vanishing retro-orbital mass in the nasopharynx compressing eyeballs. Image by Dr. Hiroiuki Yano. #ACR18 @RheumNow https://t.co/1irkBkFvLd
Nicole Bitencourt @NicoleBitencou5 ( View Tweet )
7 years 9 months ago
In pts with #SystemicSclerosis, cardiac MRI with T1 mapping sequence revealed microscopic #MyocardialFibrosis in 53% of pts and was associated with #cardiovascular events (7 heart rhythm disorders, 2 heart failure, 1 unstable angina) Abstract2934 Dr.Terrier #ACR18 @RheumNow
Nicole Bitencourt @NicoleBitencou5 ( View Tweet )
7 years 9 months ago
In #SystemicSclerosis, pts with esphageal erosions on EGD had a greater decline in FVC and progression of #ILD. Emphasizes role of micro-aspiration of gastric contents in #pathogenesis of #ILD in #scleroderma. Abstract 2936 Dr. Silvia Laura Bosello #ACR18 @RheumNow https://t.co/20hOAfS6rw
Nicole Bitencourt @NicoleBitencou5 ( View Tweet )
7 years 9 months ago
Abstract 648 OptiRef self report questionnaire for early diagnosis of a spa - 19% had confirmed diagnosis vs 40% ref from Dr. Looks useful! #AS @rheumnow #ACR18
Philip Gardiner @PhilipGardiner ( View Tweet )
7 years 9 months ago
Abst 651 Baraliakos MRI reports on SI joints in #AS differ between radiologists and rheumatologist: edema+erosion works best @RheumNow
Philip Gardiner @PhilipGardiner ( View Tweet )
7 years 9 months ago
Abstr 837 Dr Colmegna: Should we use high dose Infleunza vaccine in #RA? Vaccines less effective in RA DB RCT low vs. High dose in 279 RApts. Showed sig. better immune response with high dose vaccine. #ACR18 @RheumNow
Philip Gardiner @PhilipGardiner ( View Tweet )
7 years 9 months ago
