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Managing CKD in Lupus Nephritis Dr. Hans-Joachim Anders explores how to treat LN patients with chronic kidney disease, balancing disease control and renal preservation. 🎯 Don’t miss these expert pearls. 👉 Full update on RheumNow: https://t.co/frHvcd1xMw #LupusNephritis https://t.co/VedtGaHkMj
Dr. John Cush @RheumNow ( View Tweet )
8 months 2 weeks ago
Soluble CD13 (sCD13) has pro-inflammatory effects & is elevated in severe COVID-19. sCD13 is chemotactic, angiogenic, & arthritogenic. In COVID-19, sCD13 was assoc w/ sCD13 severity, ethnicity, inflammation markers, NETosis, & vascular injury/thrombosis. https://t.co/dTT9X49DIt
Dr. John Cush @RheumNow ( View Tweet )
8 months 2 weeks ago
Full read overview of Discoid Lupus. https://t.co/aXgveR2NwF https://t.co/9JK6CNqedO
Dr. John Cush @RheumNow ( View Tweet )
8 months 2 weeks ago
Risk Factors for Knee Osteoarthritis New research from the University of Sydney reveals that obesity, having a knee injury and occupational risks such as shift work and lifting heavy loads are primary causes of knee osteoarthritis. https://t.co/Kc686Zc8Xa https://t.co/PtyLU6jBkp
Dr. John Cush @RheumNow ( View Tweet )
8 months 2 weeks ago
Lupus Unlocked: Journal Club In this first webinar of RheumNow's Lupus Unlocked campaign, Journal Club discussed two articles: Efficacy and Safety of Obinutuzumab in Active Lupus Nephritis. Furie R, et al. NEJM. 2025 Feb 7. doi: 10.1056 Efficacy and safety of voclosporin https://t.co/OYv5J8VpRB
Dr. John Cush @RheumNow ( View Tweet )
8 months 2 weeks ago
Betw 2005 -2021, there was a substantial increase in HCQ use, but only modest steroid (GC) reductions. Swedish cohort study of 3891 SLE pts - over 5 yrs GC decr from 68% - 54% to 46%. HCQ increased by 29% over 5 years. https://t.co/sI7JWq3AGk https://t.co/RBUMcl8uGz
Dr. John Cush @RheumNow ( View Tweet )
8 months 2 weeks ago
Emulation trials in SLE: Real or Fake? Recently a landmark paper was published in A&R studying the results of an emulation trial. My colleagues and I were able to write an editorial on this paper and describe emulation trials. https://t.co/0ulYG5xz0J https://t.co/8oj8UDV9Dd
Dr. John Cush @RheumNow ( View Tweet )
8 months 2 weeks ago
New Steroid Rules in Lupus? Let’s Talk. Dr. Michelle Petri breaks down the latest strategies to minimize steroid exposure while managing disease activity in lupus patients. 💡 Smarter steroid use = better outcomes. 👉 Watch now on RheumNow: https://t.co/vbjrXAlixz #Lupus https://t.co/04CjTkCqMJ
Dr. John Cush @RheumNow ( View Tweet )
8 months 2 weeks ago
Telitacicept, recombinant fusion protein targeting BLyS & APRIL, studied in 41 Chinese SLE pts (added to standard Rx) showed mean improvements in SLEDAI-2K (10.0 to 6.25 @12 wks & 4.2 @24 wks;p<.001), daily prednisone (21 mg to 9.8mg) & proteinuria (2.8 gr to 1.3 gr/day) https://t.co/KHMWPeq79x
Dr. John Cush @RheumNow ( View Tweet )
8 months 2 weeks ago
Metanalysis of ANCA-associated vasculitis with interstitial lung disease (8 studies, 654 pts shows the following significan mortality risk factors: age (HR 1.06), ever smoker (HR 1.61), UIP pattern (HR 2.07), acute exacerbation (HR 2.73) & microscopic polyangiitis (HR 4.03). https://t.co/Rf6c2gidpK
Dr. John Cush @RheumNow ( View Tweet )
8 months 2 weeks ago
Tuesday Night Rheumatology: 🔓 Lupus Unlocked: Cutaneous SLE Join us for a discussion of the diagnosis, management, and latest insights into cutaneous manifestations of SLE. Featuring: Dr. Victoria P. Werth Dr. Matilda Nicholas Dr. Anthony Fernandez Dr. Christopher Richardson https://t.co/UNazbo9TuZ
Dr. John Cush @RheumNow ( View Tweet )
8 months 2 weeks ago
Retrospective study of 131 childhoold SLE pts found lymphopenia (in 53%) significantly correlated w/ higher anti-dsDNA and increased disease activity. (r = −0.63). Lymphopenia assoc w/ more nephritis (72%), HTN (24%), leukopenia (36%) & neuropsychiatric SLE https://t.co/ONUm84jThE
Dr. John Cush @RheumNow ( View Tweet )
8 months 2 weeks ago
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