ANA neg, but ENA pos should we care about that result? PPV 5.5% here (similar to 6% prev @EricFMorand: https://t.co/Hyaued3rw2) and how many really needed the serology? Anxiety? Surely pos ENA w neg ANA might be more hassle than help. So what to do?⬇️ #ACR24 ABST1930 @RheumNow https://t.co/rE7RmgOGey

Should you worry about giving TNFi to RA pts after a cancer diagnosis? Medicare data with colorectal, lung, prostate Ca: TNFi pts survival no worse (numerically better) than csDMARDs Cancer pts deserve good RA treatment! #ACR24 ABST0202 Suarez-Almazor @MDAndersonNews @RheumNow https://t.co/w58MNqRt1T

Probably no surprise, but if you can navigate the digital world, it portends work for your rheum disease. all @MedUni_Wien rheum clinic pts did an eHealth survey high eHealth literacy did much better We can't leave digital stragglers behind! #ACR24 ABST1942 @Stiddyo @RheumNow https://t.co/c9IyPz6ujJ

Now we have GWAS, we are getting polygenic risk scores for RA, and we can see what disease risks cluster with RA risk. RA genetic risk clusters with risk for: type 1 diabetes thyroiditis multiple sclerosis What draws these diseases together? #ACR24 ABST1365 @RheumNow https://t.co/28gU1nBEUG

Upadacitinib in Behcet's disease - would be very much welcomed, and this open label 8 patient pilot from China is encouraging. We saw similar data for tofacitinib before @ARD_BMJ: https://t.co/YlAQVXpnTY JAKi (?generic) could be a fantastic option! #ACR24 ABST2515 @RheumNow https://t.co/65friNLUOK

Effective RA therapy is about more than just joints 🇪🇸 RA cohort TNFi for first 24w led to: Lean mass index i.e. muscle going up Fat mass index i.e. fat trending down Muscle & fat composition are important Systemic Rx can deliver systemic benefits #ACR24 ABST1348 @RheumNow https://t.co/mZjcHwxMgW

Steroids in checkpoint inhibitor rheumatic irAEs need to be approached with caution. Persistent higher doses earlier on might dampen ICI response. @HSpecialSurgery ICI-IA (inflamm arthritis) cohort big diff in survival based on early steroid exposure #ACR24 ABST1989 @RheumNow https://t.co/3WAZ3ZLbFw

Dentition is important in RA, but it's easy to forget it's a matter of life or death. NHANES data shows fewer teeth strongly correlates with higher mortality (esp cardiovascular). Missing teeth = CV death HR >30 Holistic dentition is holistic RA care #ACR24 ABST1325 @RheumNow https://t.co/Z40bSFybuS

Rheumatic irAEs can get on the CAR-T bandwagon, too! CAR-T can invoke new rheumatological issues (not just cytokine release) - see @DrGomezPuerta's experience. Infrequent, but if CAR-T in general becomes common, yet another job for us to attend to... #ACR24 ABST2004 @RheumNow https://t.co/xBSlhUdkNr

Now that nipocalimab is approved for Sjogren's Disease, what about vaccination response whilst on this FcRn inhibitor (inherently lowers IgG)? Actually, not bad: takes a little longer to get there, but reassuring! (always fun to get to know a new med) #ACR24 ABST1988 @RheumNow https://t.co/IYqIGo5xVP

Active early RA accentuates regional MSK pain. Non-articular pain: easy to ignore & focus on active RA yes, some is related to RA dx activity BUT actually it becomes a bigger issue over time Worth identifying to: clarify what isn't RA Rx appropriately #ACR24 ABST1335 @RheumNow https://t.co/iN5rsyr7Bx