Tweets
 
      What are the RFs for progression of Pso to PsA? 
🔸PsO disease severity - 3.2x risk —>PsA
🔸Phenotype - nail involvement
🔸Obesity - 6x higher risk of developing PsA
🔸MSK symptoms - arthralgia & heel pain
#ACR25 @RheumNow https://t.co/UPXuxBPyKI
               
          
      
      
        
    
  Links:
         sheila @RHEUMarampa  (  View Tweet )
        
        
          4 days 9 hours ago 
        
       
      The severity of skin psoriasis increases the risk of psoriatic arthritis. Scher J @RheumNow #ACR25 https://t.co/EI0ACWACHy
              
      
      
        
    
  
         Antoni Chan MD (Prof) @synovialjoints  (  View Tweet )
        
        
          4 days 9 hours ago 
        
       
      SGLT-2 inhibitors and the prevention of autoimmune rheumatic disease 
SGLT-2 inhibitors offer benefits beyond glycemic control, such as cardioprotective and nephroprotective effects, and modest weight loss. A recent study also suggests they may have immunomodulatory effects and https://t.co/grsgHFQic5
      
      
        
    
  
         Dr. John Cush @RheumNow  (  View Tweet )
        
        
          4 days 10 hours ago 
        
       
      Is tocilizumab equally effective in ischemic vs. non-ischemic GCA?
Ischemic = vision, jaw claudication, or CVA
Remission at 6 mo higher in non-ischemic group then with equalization at month 12
No major difference in GCs at month 12
@RheumNow #ACR25 #Abst0739 https://t.co/OeYggSQYx8
              
      
      
        
    
  
         Brian Jaros, MD @Dr_Brian_MD  (  View Tweet )
        
        
          4 days 10 hours ago 
        
       
  
      RA may age the immune system by nearly two decades.
IgG glycome profiles showed inflammatory aging even in early RA, tied to low fitness & high inflammation.
Improving muscle & fitness may help reverse this biologic clock.
@RheumNow #ACR25 Abstract #0835
    
        Jiha Lee @JihaRheum ( View Tweet )
        4 days 10 hours ago 
      
     
      We need more biomarkers in GCA - what about fibrinogen?
Miller et al retrospectively compared CRP, ESR, and fibrinogen at different points in GCA dx
Fibrinogen (and ESR/CRP) only helpful prior to initiation GC with comparable performance
@RheumNow #ACR25 Abst #0750 https://t.co/q5gFxDMnTy
              
      
      
        
    
  
         Brian Jaros, MD @Dr_Brian_MD  (  View Tweet )
        
        
          4 days 10 hours ago 
        
       
      Can tissue give us an underlying diagnosis in aortitis? 
Dr. Kermani breaks down the autoimmune differential based on histopathology
@RheumNow #ACR25 https://t.co/twcH021dxS
              
      
      
        
    
  
         Brian Jaros, MD @Dr_Brian_MD  (  View Tweet )
        
        
          4 days 10 hours ago 
        
       
  
      Abstract 0842
💡 Urinary biomarkers as the next frontier for monitoring lupus nephritis activity
🔹 Proteinuria didn’t track w/ histologic activity
🔹 IL-16 & sCD163 correlated at baseline only
🔹 Urinary Tenascin C & BAFF correlated w/ activity at 1 yr
@RheumNow  #ACR25
    
        Akhil Sood MD, MS @AkhilSoodMD ( View Tweet )
        4 days 10 hours ago 
      
     
      2 year extension data from SELECT-GCA:
Patients in remission who remained on upadacitinib 15mg daily after 1 year had 90% reduced risk of flare compared to those who switched to placebo
Higher rates zoster, CK elevation in UPA group
#ACR25 @RheumNow #ACRBest https://t.co/jf8Dh2wCBj
              
      
      
        
    
  
         Brian Jaros, MD @Dr_Brian_MD  (  View Tweet )
        
        
          4 days 10 hours ago 
        
       
      The differential diagnosis for CNS vasculitis is BROAD. Keep in mind it’s mimics @RheumNow #ACR2025 https://t.co/ASWr6zm5eQ
              
      
      
        
    
  
         Gabriela Martinez Zayas, MD @MartinezZayasMd  (  View Tweet )
        
        
          4 days 10 hours ago 
        
       
  
      Social media based outreach to pts for research 
Out of 617,207 users engaged, 6 filled the contact form
Based on this social media (knowing also promotion costs) might not be the best strategy to recruit for clinical trials
@RheumNow #ACR25 https://t.co/qCH9WXyTD7
    
          
        Aurelie Najm @AurelieRheumo ( View Tweet )
        4 days 10 hours ago 
      
     
      💊  SGLT2i vs GLP-1 in Lupus Nephritis
TriNetX evaluating the impact of GLP-1 agonists vs SGLT-2 inhibitors on outcomes of lupus nephritis
📊 GLP-1 use linked to better renal & CV outcomes in LN including:
⬇️ CKD progression 
⬇️ Mortality
⬇️ Acute MI
@RheumNow #ACR25 https://t.co/v4LgKFDt68
              
      
      
        
    
  
         Akhil Sood MD, MS @AkhilSoodMD  (  View Tweet )
        
        
          4 days 10 hours ago 
        
       
        
    

