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πŸ’Š After TNFi failure in axSpA, switch to IL-17Ai or cycle TNFi? ROC-SpA (Phase 4 RCT, n=300): NO difference: ASAS40 15.2% vs 14.5% at week 24 #OP0235 #EULAR2026 @RheumNow https://t.co/45gisWiuoM
Nelly ZIADE πŸ€ @Nellziade ( View Tweet )
2 months 3 weeks ago
πŸ”¬ Can filgotinib improve axSpA? OLINGUITO (Phase 3 RCT, n=495): YES! ASAS40 39.5% vs 21% (r-axSpA) at week 16 #OP0234 #EULAR2026 @RheumNow https://t.co/0vj2KqSS1b
Nelly ZIADE πŸ€ @Nellziade ( View Tweet )
2 months 3 weeks ago
βš–οΈ Does BMI outrank treatment in early PsA outcomes? YES - SPEED trial AI analysis: BMI #1 predictor of PASDAS at 1yr in 192pts #OP0187 #EULAR2026 @RheumNow https://t.co/9cZG7AWau2
Nelly ZIADE πŸ€ @Nellziade ( View Tweet )
2 months 3 weeks ago
Good news! #Survival in #SLE is improving #SLR of #lupus publications over time in 233 publications Bad news - still a mortality gap! #EULAR2026 @RheumNow @eular_org ABST#POS0684 https://t.co/PVmQI2duYS
Janet Pope @Janetbirdope ( View Tweet )
2 months 3 weeks ago
πŸ’‰ Does bimekizumab work in real-world PsA? YES - EuroSpA: 76% retention at 6months 46% DAPSA LDA in 787pts across 12 registries #OP0185 #EULAR2026 @RheumNow https://t.co/TXS3r9mZXB
Nelly ZIADE πŸ€ @Nellziade ( View Tweet )
2 months 3 weeks ago
🧲 Does GUS+GOL combo beat GUS alone on MRI in PsA? YES for joints - AFFINITY Phase 2a RCT: greater MRI inflammation reduction in 91pts #OP0186 #EULAR2026 @RheumNow https://t.co/9eIS6lh7WN
Nelly ZIADE πŸ€ @Nellziade ( View Tweet )
2 months 3 weeks ago
Sustained remission in #SLE at 5 yrs w CAR-T 8 severe SLE patients treated with autologous CD19-CAR T cells (Zorpocel; Miltenyi Biomedicine) #antiDNA and #SLEDAI #antiSm ➑️prolonged suppression Big ? - how long will it work for Impressive! @RheumNow #EULAR2026 #EULARbest #729 https://t.co/8iOSImX3w6
Janet Pope @Janetbirdope ( View Tweet )
2 months 3 weeks ago
🧬 Do biomarkers predict #zasocitinib response in PsA? YES: TYK2/IL-17 pathway markers predict ACR20 in 290pts Phase 2b RCT #OP0184 #EULAR2026 @RheumNow https://t.co/AVlyrauI5q
Nelly ZIADE πŸ€ @Nellziade ( View Tweet )
2 months 3 weeks ago
πŸ”Ž Can US predict PsA progression from psoriasis? YES: synovio-entheseal inflammation predicts progression in 183pts prospective cohort #OP0183 #EULAR2026 @RheumNow https://t.co/7B9KU60qFd
Nelly ZIADE πŸ€ @Nellziade ( View Tweet )
2 months 3 weeks ago
🦴 What drives enthesophytes in PsA? SITE-SPECIFIC: Pelvic driven by disease activity+BMI Calcaneal by BMI+damage in a 1596pts cohort OP0182 #EULAR2026 @RheumNow https://t.co/4RxgjJ2V9u
Nelly ZIADE πŸ€ @Nellziade ( View Tweet )
2 months 3 weeks ago
❀️ Do biologics differ in MACE risk in PsA? YES - JAKi highest risk after 2.5yrs vs TNFi/IL-17i/IL-23i in a retrospective cohort of 22,246pts. OP0181 #EULAR2026 @RheumNow https://t.co/eQdBtMfRAY
Nelly ZIADE πŸ€ @Nellziade ( View Tweet )
2 months 3 weeks ago
Treatment for #lupus #brain #fog?! #small #RCT of Memantine a N-methyl-D-aspartate receptor (NDAR) antagonist used in #Alzheimers SLE-more permeability in #brain #SLE -antiDNA cross reacting w NDAR #memantine N=19 v #PBO N=25 showed more improvemt #EULAR2026 @RheumNow POS701 https://t.co/qvHOy9oDS7
Janet Pope @Janetbirdope ( View Tweet )
2 months 3 weeks ago
DESIR Cohort 10-year data (OP0102): SIJ structural lesions in #axSpA progress slowly, but prior MRI bone marrow oedema predicts later structural damage. bDMARD exposure was associated with less erosion progression supporting early biologic treatment Abstr OP0102 @RheumNow

Antoni Chan MD (Prof) @synovialjoints ( View Tweet )

2 months 3 weeks ago
Male sex independently associated with greater mSASSS increase (Ξ² 0.29), higher odds of β‰₯2-unit mSASSS progression (OR 2.08), and new syndesmophyte formation (OR 1.90) in #axSpA despite lower disease activity scores. Treat symptoms and progression Abstr OP0101 @RheumNow

Antoni Chan MD (Prof) @synovialjoints ( View Tweet )

2 months 3 weeks ago
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