AutoAbs in poly/dermatomyositis - ANA+ 50% to 80%, but not helpful in Dx. Look for MSA Abs - espec antisynthetase ABs (anti-Jo-1), but also newer Abs: MDA-5, TIFF-1 gamma, NXP-2 (to be discussed #RNL24 Dr. Christopher-Stine) https://t.co/ZRlMPE48qX https://t.co/kxD1jw832C https://t.co/afC617tbmq

Sarcopenia Linked to Smoking in Osteoarthritis Sarcopenia commonly has been linked to aging and arthritis and contributes significantly to quality of life and outcomes, but the association between sarcopenia and OA has not been well established. https://t.co/anZMTGnFej https://t.co/TgVg3xpiWI

Biomarker Predicts Survival in Autoimmune Lung Disease One major subgroup of patients with ILD arising from polymyositis/dermatomyositis (PM/DM) survived significantly longer when serum levels of interferon-λ3 were relatively low, researchers found. https://t.co/PcTmzavJuC https://t.co/cNL3iTSGiF

Sarcopenia Linked to Smoking in Osteoarthritis Sarcopenia commonly has been linked to aging and arthritis and contributes significantly to quality of life and outcomes, but the association between sarcopenia and OA has not been well established. https://t.co/ucEWJjZ8Zv https://t.co/MeHw56vLjj

GNSC-001 gene therapy w/ a recombinant adeno-assoc. viral vector expressing IL-1Ra, to block IL-1. GNSC-001 now in a phase Ib, 50 pt, 10 center USA trial to assess its efficacy in Knee OA. Given as single injx in the affected joint; results in late 2024 https://t.co/jW9FHlGyC2 https://t.co/Dbv15Flqlv

New download on ChatGPT available! https://t.co/mZc5Ex2vU9 https://t.co/DyfZepwFOD

Do I have Arthritis? How I handle this frequent curbside consult question... https://t.co/uX6MUfy59w https://t.co/kYviOhcLQj

Metanalysis of CNS Lupus, 44 studies, 17 865 early- (<50y) vs 2970 late-onset SLE (>50y) pts. CNS LE in 16%, more common in younger LE (OR: 1.41). Early-LE had more seizures (OR: 1.68), psychosis (OR: 1.72). Older - more Peripheral neuropathy (OR: 0.64) https://t.co/XoJjIH69t6 https://t.co/sRyV7A07gA

Biomarker Predicts Survival in Autoimmune Lung Disease One major subgroup of patients with ILD arising from polymyositis/dermatomyositis (PM/DM) survived significantly longer when serum levels of interferon-λ3 were relatively low, researchers found. https://t.co/9c9DjOIeoI https://t.co/fBpvjODybd

In Norway incidence of #SLE is decreasing, esp in women 50-59 years. Population study of 1558 confirmed SLE; 797 had new-onset betw 1999-2017. In older women 50-59 yrs incidence fell 3.4 to 1.1/100K (also 74% reduction in menopausal HRT https://t.co/Z1falNwLlD https://t.co/bJ3cXKueKg

Small study of 33 #AAV pts and 21 controls shows nailfold capillaroscopy of no value in diagnosing/assessing AAV pts. https://t.co/uRFDBbLVJq https://t.co/pVETSFlBsp