Tweets
Report of 54 Sjögren dz pts w/ cutaneous vasculitis (CV); most had cryoglobulinemic vasculitis & hypergammaglob.vasculitis. Sjogrens w/ CV had higher risk of lymphoma. Type II cryoglob. vasculitis incr risk of mortality/lymphoma, renal dz, peripheral nerve involvement https://t.co/Yd1iu9ZJX0
Dr. John Cush @RheumNow ( View Tweet )
1 month 1 week ago
QD Clinic: ILD with Positive SSA and Rash
Dr. Elena Joerns, Rochester, Minnesota discusses a case of ILD with positive SSA and rash, as part of RheumNow's Rheum to Breathe: ILD campaign, presented throughout the month of September 2025.
https://t.co/Yuz8CuIN5H https://t.co/3M9emsIXVf
Dr. John Cush @RheumNow ( View Tweet )
1 month 1 week ago
ILD and ANCA: What to do?
Several cohort studies conducted in Asia, Europe and the Americas have evaluated the clinical significance of ANCA when detected in patients with ILD as well as the types of ILD encountered in patients with microscopic polyangiitis (MPA) and their https://t.co/nrToywCaKm
Dr. John Cush @RheumNow ( View Tweet )
1 month 1 week ago
Rheum to Breathe Journal Club
In this journal club, we will discuss two pivotal studies in ILD, the FIBRONEER study and the RECITAL study: Nerandomilast in Patients with Progressive Pulmonary Fibrosis, Maher, T.M. et al. NEJM. 2025 May 19.
https://t.co/L0gIsP5nAn https://t.co/026GbJdCvJ
Dr. John Cush @RheumNow ( View Tweet )
1 month 1 week ago
Screening for RA-ILD: metanalysis of 9 studies, 1380 RA pts - RA-ILD prevalence ranged from 6.7-42.7%; 18.9% via HRCT. None examined risk factors. Male sex & smoking were ~12% higher in RA-ILD & RA disease onset age was 7 years higher in RA-ILD pts. DAS didnt https://t.co/qA2oitwQg5
Dr. John Cush @RheumNow ( View Tweet )
1 month 1 week ago
CAR-T Product Shows Early Promise in Lupus
Five patients with systemic lupus erythematosus (SLE) in China have been treated with a potentially groundbreaking form of chimeric antigen receptor (CAR) T-cell therapy, researchers reported, with encouraging results after 3 months. https://t.co/eg37PZK6kn
Dr. John Cush @RheumNow ( View Tweet )
1 month 1 week ago
PPP syndrome = a rare triad
👉 Pancreatitis + Polyarthritis + Panniculitis
🔬 Pathogenesis: circulating pancreatic enzymes (esp. trypsin) → fat necrosis in subcutis & bone marrow.
📌 Clue: painful nodules + arthritis, often with minimal abdominal symptoms.
#Rheumatology https://t.co/3qniCmahgl
ILLIASUL IBAD @IlliasulK ( View Tweet )
1 month 1 week ago
Inception SLE study of 674 pts (without LN), mean age 34 yrs - 154 (23%) developed new proteinuria (LN) after median of 3.6 yr. Cumulative antimalarial exposure did NOT lower risk of LN (HR 0.98; 0.94-1.02); same for those w/ serologically active SLE (HR 0.97) https://t.co/8OU3yJAvhN
Dr. John Cush @RheumNow ( View Tweet )
1 month 1 week ago
OL study of 60 pts w/ new idiopathic retroperitoneal fibrosis (GFR >30) Rx w/ low dose MTX+pred VS Pred only. @ 9 mos remission: 90% MTX+Pred vs 81% Pred (noninferior). Time-to-remission, RPF thickness & relapses were same; but pred use was lower w/ MTX+pred (p < 0.001) https://t.co/13cjnl4Ke4
Dr. John Cush @RheumNow ( View Tweet )
1 month 1 week ago
Turkish study of 799 psoriasis pts - 30% had concurrent onset PsO & PsA & in 70% there was a long transition time (~13 yrs) from PsO-to-PsA. Factors assoc w/ prolonged interval included Depression, fatigue, scalp PsO(OR 7), nail PsO (3.2), +Fhx & enthesitis ever (OR 2) https://t.co/wqtSbeQ2vz
Dr. John Cush @RheumNow ( View Tweet )
1 month 1 week ago
Canakinumab in VEXAS - 47 males Rx w/ anakinra (44), canakinumab (9), or both(6). Response @1 mos: ANAK 34% vs CANK 100%; 22% vs 78% @ 3 mos. Drug survival was 54 mos CANK 300/m; 7 mo CANK 150/m; 1 mo ANAK. More ISR (47% v 0) & infx w/ ANAK https://t.co/Y3iSfajTal https://t.co/qTNamGDwVI
Dr. John Cush @RheumNow ( View Tweet )
1 month 1 week ago
Prospective French study of 101 RA-ILD (mean 66yrs) assessed for shorter WBC telomere length (LTL); short LTL seen in 43% & assoc w/ lower FVC (82% vs 93%pred) & TLCO (49% vs 63%) & greater FVC/DLCO decline & lung progression after 12 mos (47% vs 22%; p<0.001) https://t.co/ObVeon0riy
Dr. John Cush @RheumNow ( View Tweet )
1 month 1 week ago


