13 Risk Factors for RA-associated Interstitial Lung Disease (ILD) ILD is the most widespread and fatal pulmonary complication of rheumatoid arthritis (RA). A recent metanalysis shows the pooled prevalence of RA-ILD was approximately 18.7%. https://t.co/oqb37RWPuZ https://t.co/tp3qBh1wRC

Pearl: Three "S" Rule (Smoking, Seropositivity, Sex/Male): if present the risk of RA-UIP (ILD) goes up nearly 13 fold (ACR23 Abstract 1269) https://t.co/heiTtarS1Y https://t.co/EkHbmMgIEC

RCT 302 Dupuytren contracture pts Rx w/ Surgery (n 101), needle fasciotomy (101), or collagenase injx (100). 292 & 284 completed; Success (>50% improved) @3 mos was same: 71%, 73% & 73%. @ 2 yrs, surgery was superior (78% vs. 50% or 65%) https://t.co/K74p1xpnZx https://t.co/xaC4pdPSFQ

JAMA: Industry Payments to Physicians ($12.13 billion 2013-22) 1 Ortho: $1,360,744,428 2 Neuro: $1,322,668,751 3 Cardio: $1,293,613,594 4 Heme/onc: $825,799,685 5 Int medicine: $588,249,423 6 Endo: $546,513,674 7 FP: $479,105,369 8 Rheum: $464,858,022 https://t.co/GCWchn9IMz https://t.co/6sRwOWm83y

soluble Fms‐like tyrosine kinase‐1 (sFlt-1)/placental growth factor (PlGF) ratio, biomarkers of placental function and adverse pregnancy outcomes. Study of 158 RA pts, 1/2 on TNFi during Preg. TNFi assoc w/ incr birthweight; no effx on sFlt‐1 & PlGF https://t.co/JFvDxrTAfr https://t.co/CRxSEbm2Ru

CDC surveillance data 2019–2021 identified cases: - 59,655 coccidioidomycosis - 3,595 histoplasmosis - 719 blastomycosis (unusually high fatality rate in 2021 of 17%; typically 8%–10%) https://t.co/cDC0nuZLsb https://t.co/Q4QkNtNvJc

FDA Curriculum and Toolkit on Biosimilars for educators; Fact sheets on: - Biologicals, Biosimilars & InterchangeableProducts - Generics & Biosimilars - Manufacturing & Variation - Biosimilar Regulatory Approval Pathway https://t.co/bHYFPb8VxU https://t.co/bA8I567H8U

There is world wide variability the prevalence of #PsA - the global prevalence=112 per 100K adults; and is more common in Europe (207/100K) and North America (64/100K) compared with Asia (37/100K) and South America https://t.co/UY25S00w26 https://t.co/AZMbZ3hG2c

Systemic Inflammation Index [SII]= PMN# x Plt # / Lymphs# (all from CBC) has predictive value. Review of 16 studies (2893 immune pts & 2346 controls). SII significantly higher in ID vs controls, active vs remission, & those w/ & W/O immune disorders https://t.co/qDDQL88wbv https://t.co/IW1fnaoJRo

ICYMI: Eating for Rheumatoid Arthritis The majority of practicing rheumatologists at RheumNow Live were unaware of the new ACR guidelines issued in 2022 regarding dietary and lifestyle recommendations for patients with Rheumatoid Arthritis (RA) (1). https://t.co/0Z1lYzsxuI https://t.co/2atX1B4hQb