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Study of 140 SLE pts shows 45–50% w/ IFN-I gene expression; all correlated w/ active skin & 2/6 w/ arthritis. IFN-induced Mx1 protein correlated with IFN-I score (P<0.0001); 25% showed high PMN expression assoc w/ fever, serositis, low WBC, steroid use. https://t.co/a3Fp3qdbkG

Dr. John Cush RheumNow( View Tweet)

2 weeks 3 days ago
Secukinumab shown to work in 9/15 (67%) of refractory Behçet’s patients (mucosal and articular dz) by 3 mos - Retrospective study looked a complete or partial responders. #s increased to 86.7% at 6 months. Doses: either 150 or 300 mg qmonth https://t.co/a3Fp3qdbkG

Dr. John Cush RheumNow( View Tweet)

2 weeks 3 days ago
FDA has approved OTC availability of Voltaren Gel - now called Voltaren Arthritis Pain: a topical NSAID, 1st approved by FDA in 2007. Indicated for the pain of osteoarthritis - It has not been effective in strains, sprains, bruises, sports injuries https://t.co/Tla75Bn4H0

Dr. John Cush RheumNow( View Tweet)

3 weeks ago

BCG & COVID: 1) Israeli study shows BCG vaccination during childhood had no protective effect on getting COVID-19 infection later. 2) Bladder cancer pts on BCG therapy who get COVID infection, can safely take IL-6 or IL-1 inhibitors, Just not TNF inhib. https://t.co/TlOj6b8Taf

Dr. John Cush RheumNow( View Tweet)

3 weeks ago
New axioms in the time of #COVID-19 1. Always assume every patient may have COVID-19 2. Always assume your Zoom camera is on. 3. Always assume your microphone is live. 4. Always assume something will be fundamentaly different next week. @medicalaxioms #covid4MDs

T. Scott Diesing, M.D. diesing_t( View Tweet)

3 weeks 1 day ago
Tuesday Nite Rheumatology Grand Rounds by Dr. Joan Merrill (OMRF) on "What Does COVID-19 Have to do with LUPUS". Watch it here>>https://t.co/q5Om4CQAnP or listen on iTunes or here>> https://t.co/yJWsmds0cg

Dr. John Cush RheumNow( View Tweet)

3 weeks 1 day ago
Interview w/ Private Practice Rheums on Covid - Drs. Herb Baraf and Danny Ricciardi. DC & Brooklyn Docs wrangle technology, Telehealth, Return to normal, the future and more. Watch it here>> https://t.co/TaMbiF9MLC or listen on iTunes or here>> https://t.co/G7sR23bwLW

Dr. John Cush RheumNow( View Tweet)

3 weeks 1 day ago
God Bless our Nurses! Happy Nurse Week! https://t.co/5TRitXfvpu

Dr. John Cush RheumNow( View Tweet)

3 weeks 1 day ago
Metanalysis shows Type 2 DM associated with >2-fold increased risk (aHR 2.25) of severe liver disease (NAFLD); a more modest risk w/ obesity (HR 1.20); other risk variables - low HDL, high triglycerides & hypertension were independently associated https://t.co/uUdARZYkqG

Dr. John Cush RheumNow( View Tweet)

3 weeks 2 days ago
Hungarian population study of incident SLE (4503 pts) and treated SLE pts (2582) finds standardized mortality ratio elevated in SLE (1.63 and 2.09). cause of death differed only for infection with infection-related deaths more common in SLE. https://t.co/IEkfShjCt1

Dr. John Cush RheumNow( View Tweet)

3 weeks 2 days ago
Study of 274 women with axSpA shows that longer time to pregnancy (TTP) was associated with older age, nulliparity, and longer disease duration. https://t.co/GznVvnPAwO

Dr. John Cush RheumNow( View Tweet)

3 weeks 2 days ago
Why are more MEN (severely?) affected in COVID-19? Men have higher levels of circulating ACE2 (unrelated to ACEi or ARB HTN meds) based on a Biobank study of 1485 men, 537 women. ACE2 is found in lungs, heart, kidneys, vessels & testes https://t.co/CWXevTNYWm

Dr. John Cush RheumNow( View Tweet)

3 weeks 2 days ago
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