Tweets
Epidemiology of Dry Eye Autoimmune Disease
Rates upwards of 20% were seen across nine common autoimmune diseases other than Sjögren's, most often in rheumatoid arthritis (39.3%) with Crohn's disease bringing up the rear (23.0%), according to Chi-Chin Sun, MD, PhD, of Chang Gung https://t.co/Z8ZBGmqT93
Dr. John Cush @RheumNow ( View Tweet )
3 months 3 weeks ago
3 Months of Romosozumab in Postmenopausal Osteoporosis
A report in The Lancet Diabetes & Endocrinology suggested that 3 months of romosozumab (ROMO) followed by denosumab is as effective at increasing hip bone mineral density (BMD) as the standard 12-month course. https://t.co/HPM7DdRFBM
Dr. John Cush @RheumNow ( View Tweet )
3 months 3 weeks ago
Early vs Delayed Belimumab in Lupus
An economic evaluation of early vs delayed use of the Blys inhibitor, belimumab (BEL), in systemic lupus erythematosus (SLE) has shown both cost-effectiveness and clinical utility of early BEL initiation in active lupus patients. https://t.co/7unHZhR6Dd
Dr. John Cush @RheumNow ( View Tweet )
3 months 3 weeks ago
Nice simple overview of SCLERITIS. https://t.co/BOgZK8y4Qq https://t.co/P0dLtA3nKy
Links:
Dr. John Cush @RheumNow ( View Tweet )
3 months 3 weeks ago
Antimitochondrial antibodies (AMA)in systemic sclerosis? Retro study of 165 SSc pts (20% diffuse, 33% ILD, 7% PAH); 51% centromere AB+; 29% topoisomerase I+, 12% RNA polymerase III+)-- 22% AMA-positive: assoc w/ GI vascular dz(OR 13.3), gastric antral vascular ectasia (OR 8) & https://t.co/FRhn9qIfOW
Dr. John Cush @RheumNow ( View Tweet )
3 months 3 weeks ago
GLP-1s are known to improved knee OA. Using a mouse OA model w/ obesity, semaglutide yielded less pain, osteophytes & had strong chondroprotective effects, fia a wt loss-independent way. Changing from glycolysis to oxidative phosphorylation resulted in cartilage restoration. https://t.co/8zs34ys9o9
Dr. John Cush @RheumNow ( View Tweet )
3 months 3 weeks ago
What did you miss at RheumNow Live 2026?
Our Poster Hall features new data across:
• Psoriatic Arthritis
• Systemic Lupus Erythematosus
• Lupus Nephritis
• Vasculitis
• Polymyalgia Rheumatica
• Axial Spondyloarthritis
From Phase III trials to real-world evidence, these https://t.co/nuXGUdmwon
Dr. John Cush @RheumNow ( View Tweet )
3 months 3 weeks ago
Systematic Review of Targeted Rx for Systemic Sclerosis: from 32 RCTs & 2036 pts Rx w/ 23 targeted agents. Guselkumab had greatest effect on mRSS, followed by tofacitinib, inebilizumab, & baricitinib. For FVC, B-cell Rx (belimumab, RTX) had highest efficacy https://t.co/cXTQ2TWyHZ
Dr. John Cush @RheumNow ( View Tweet )
3 months 3 weeks ago
A month ago the FDA Granted Breakthrough Designation to Ianalumab for Sjögren Disease . The drug targets BAFF and depletes B cells. Two recent positive RCTs (NEPTUNUS-1, NEPTUNUS-2). Novartis expects a regulatory decision in early 2026 https://t.co/PXVjGG1Cmd https://t.co/0s5livw1bg
Dr. John Cush @RheumNow ( View Tweet )
3 months 3 weeks ago
FDA has approved tocilizumab-anoh (Avtozma; Celltrion), a biosimilar to Actemra, for intravenous and subcutaneous use in rheumatoid arthritis (RA), giant cell arteritis, polyarticular juvenile idiopathic arthritis, systemic juvenile idiopathic arthritis, and COVID-19. https://t.co/qw7SJ7ZCK9
Dr. John Cush @RheumNow ( View Tweet )
3 months 3 weeks ago
Taiwan National retrospective study (2001-20) of 8732 newly Dx, biologic-naïve RA pts initiating b/tsDMARDs. Found no difference in malignancy event rates between DMARDs. 2.16% over 5-yr & 2.89% over 18yrs. (6384 Rx w/ TNFis, 667 w/ TCZ, 656 w/ ABA, 1025 on tsDMARDs) https://t.co/54ZMPywEYI
Dr. John Cush @RheumNow ( View Tweet )
3 months 3 weeks ago
Should I become a physician or physician assistant/associate? Practical overview from US News. KEY QUESTIONS: 1) which is harder to get into? 2) Career flexibility? 3) Work-Life balance? 4) Which fits for you? Both are a lifelong commitment to patient care. https://t.co/szv1nUmkYQ
Dr. John Cush @RheumNow ( View Tweet )
3 months 3 weeks ago


