Evidence-Based Guidelines for EGPA Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare form of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis, affecting between 10 and 14 cases per million globally. https://t.co/VixECcPv4R https://t.co/XgEHRgDiPj

RELIEF Trial: Sublingual Cyclobenzaprine in Fibromyalgia https://t.co/a6KUPcfmxM https://t.co/ToRJQVsZSu

RCT of 122 active plaque Psoriasis pts (38F, 55M) with low vitamin D (~15). Rx w/ either PBO or Vit D (100K IU, followed by 20K IU/wk x 4 mos). Vitamin D supplementation had no effect on psoriasis severity (but pts had mild PSO). https://t.co/JXtEBaop3c https://t.co/ScGtBUIrm0

Subanalysis of the tofacitinib ORAL Surveillance study shows the JAK "at-risk" population are patients Age ≥65 years or ever smoker who exhibited the excess adverse events (malignancies, MACE, MI, VTE, all-cause death) comparedd to TNFi (HRs 1.41–5.19) https://t.co/k78WsPR1Mv https://t.co/JmTDSctIa0

Juvenile and Adult-onset Scleroderma Differ A retrospecitve cohort comparision of juvenile (jSSc) and adult-onset (aSSc) systemic sclerosis (SSc) are both rare but present differently. https://t.co/57OrgaUNqj https://t.co/Y2puN18ux0

Black Tongue discoloration in 80 yr old w/ 5 d of fever & shoulder pain, Dx as septic arthritis from Staph. aureus (Rx/ IV cefazolin). Black tongue from Abx? (cephalosporins, PCN, tetracyclines, erythromycins, doxycycline, metronidazole moxifloxacin) https://t.co/lJ91yXOvQ9 https://t.co/mYqwCj3VEL

ICYMI: Our old friend, hydroxychloroquine https://t.co/NouJayD0T3 https://t.co/lRBl0UQuY3

Conaghan shares unpublished data from PROMOTE study at #RNL2023 Early data shows MTX benefits pain in patients w/ OA, particularly more metabolically active. Looking forward to more data on this-- https://t.co/Zfh7CbqvPi https://t.co/kIYKRFtUX2

Metanalysis of 38 studies(458,256 pts). Diabetes was seen in 19% of hyperuricemic and 16.7% of gout pts - an even higher DM prevalence was seen in North America (20.7%) https://t.co/AYVWaditxG https://t.co/T4fedCSpx1

Matched cohort study of 67,598 German primary care Pts shows gout have incr risk of breast cancer (4.5% gout vs 3.7% non-gout; HR: 1.17; 1.05-1.31). Association only seen under age 50 (HR: 1.58; 1.10-2.27), but notin women over 50 yrs https://t.co/pl6gH2GyZQ https://t.co/VR8kuumhNv

What happens to PsA in pregnancy? 1/3 with mod-severe disease Little evidence of change of disease activity in pregnancy Disease may increase post-partum Christina Chambers @mothertobaby #RNL2023 @RheumNow https://t.co/0QAxhHb45u https://t.co/zb0YSaqiOf

DMARDs/TNF for PMR: MTX- initial benefit, but no 5 year steroid sparing effect Infliximab - no benefit Lef - some benefit in case series Robert Spiera #RNL2023 @RheumNow https://t.co/d7BpmxFfct https://t.co/jLJDPuMtD3