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Atopic Disease Increases Osteoarthritis Risk Analysis of commercial insurance claims suggests that patients with asthma or atopic dermatitis have a significantly increased risk of osteoarthritis (OA). https://t.co/450DnhOfY5 https://t.co/zUfD4jhumY
Dr. John Cush @RheumNow ( View Tweet )
3 years 3 months ago
Frunevetmab (Solensia), is a cat-specific mAb against nerve growth factor was FDA approved, for use in CATS, to treat the pain of osteoarthritis. CATS! https://t.co/vY0CCMjZmC https://t.co/UnpDpo5fyB
Dr. John Cush @RheumNow ( View Tweet )
3 years 3 months ago
Tomorrow! Join us for Tuesday Night Rheumatology. Our panelists will discuss the challenges they have faced trying to manage a career and family life, as well as provide advice and strategies for managing competing priorities and obligations. https://t.co/OlP0pupkMV https://t.co/pZQMASafcG
Dr. John Cush @RheumNow ( View Tweet )
3 years 3 months ago
Abbvie has completed a phase II upadacitinib vs combo elsubrutinib/upadacitinib ( ABBV-599) in active #SLE - M19-130 (SLEek) Phase 2 trial met the primary endpoint SRI-4 response and pred dose<=10 mg qd. No new safety signals - Phase III trial planned https://t.co/6CwS2AVamH https://t.co/b4wQ6IoiOz
Dr. John Cush @RheumNow ( View Tweet )
3 years 3 months ago
Gender Gap in Editors. Cross-sect study of top 10 Intl medical journals in 41 categories shows women underrepresented as editors in chief. Women editors=21%. No women editors in dentistry, oral surgery; allergy, psychiatry; anesthesiology; ophthalmology https://t.co/JWAwrO9F4w https://t.co/0viEMa6ImK
Dr. John Cush @RheumNow ( View Tweet )
3 years 3 months ago
Variability in rheumatologist steroid prescribing - using data on ~500k RA pts and 6,875 rheumatologists. Those LESS likely to prescribe alot of steroids were: women, solo practitioners, in practice ≥10 years, seeing greater#s of RA pts/year https://t.co/ELk0avorOe

Dr. John Cush @RheumNow ( View Tweet )

3 years 3 months ago
Open-label Trial of 14 pts with MAS due to steroid refractory systemic JIA or adult-onset Still’s demonstrated the efficacy of IV emapalumab, an anti-IFNγ mAb. Demonstrated signif reductions in LDH, sIL-2R, Ferritin, CXCL9, & steroid dose https://t.co/vgxT5KzmQF https://t.co/gDLmfOlSHG
Dr. John Cush @RheumNow ( View Tweet )
3 years 3 months ago
Mom in Medicine BINGO - Just try to Win! #WIR https://t.co/Mb4KtsWQPK

Dr. John Cush @RheumNow ( View Tweet )

3 years 3 months ago

LAVLI - A New Autoinflammatory Disorder NIH researchers have have described a novel autoinflammatory disorder called "Lyn kinase-associated vasculopathy and liver fibrosis" (LAVLI), based on a mutation in the LYN gene. https://t.co/RYmb3QFB1T https://t.co/sn5hwVxwPk

Dr. John Cush @RheumNow ( View Tweet )
3 years 3 months ago
2022 EULAR Recommendations for ANCA-associated Vasculitis EULAR has published the 2022 update on recommendations for the management of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). https://t.co/lvPO26S0k6 https://t.co/cQtiEctrTR
Dr. John Cush @RheumNow ( View Tweet )
3 years 3 months ago
30 consecutive seropositive (CCP or RF+) early RA pts - 60% had pulmonary abnormalities (PA). PA correlated with presence of neutrophil activation, parameters of inflammation and RF titres. https://t.co/dsbjPhuYzf https://t.co/1Zmyqjuaxj
Dr. John Cush @RheumNow ( View Tweet )
3 years 3 months ago
Autoimmune-Rheum Dz (AIRD) flares occur in 10% w/ COVID vaccination, esp in pts w/ comorbidities, autoimmune morbidities & mental health disorders & Moderna vaccine. 3453 AIRD pts who recv Vax 9.5-11.3% had clinical flares (Arthritis 62% & fatigue 59%) https://t.co/C0WA2Znixl https://t.co/vXzL8XR7kd
Dr. John Cush @RheumNow ( View Tweet )
3 years 3 months ago
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