Metanalysis of 3 RCTs & 19 observational studies, showed hematopoietic stem cell transplantation . (HSCT) significantly improved skin thickness and lung function. While HSCT had more deaths than IV CTX, HSCT had higher 2 yr survival rate https://t.co/FMWFfmYPod https://t.co/SFjlj1yV0x

Metanalysis shows Takayasu's arteritis pts are at higher risk of adverse pregnancy outcomes. (27 studies, 825 pregs) showed more miscarriage (16%), hypertension (37%) and pre-eclampsia (14%) in TA patients (p < 0.01) https://t.co/stVx5jvPsj https://t.co/LaftdsHmSz

Does Methotrexate Work in Alopecia Universalis? Alopecia areata totalis (AT) and universalis (AU) are the most severe and difficult to treat forms of alopecia areata (AA). https://t.co/x8EjMekMBJ https://t.co/ntejSJcG5M

CDC says EVERYONE should be tested for Hepatitis B al least once, w/ 3 lab - HBsAg, & Abs to hepatitis B surface Ag (anti-HBs), hep B core Ag (anti-HBc). At increased risk for HBV - persons in jail, +Hx of STDs, multiple sex partners or Hx of hepatitis C https://t.co/DRzAuhVJSJ https://t.co/9ma0I61xeD

Population study from Japan shows that Aging is an independent contributor for seronegative RA in patients who are female, have a nonsmoking history, and a BMI < 25. https://t.co/WWRGczmc4K https://t.co/ZHRIHlxDIK

1215 pts w/ refractory SJS/TEN (not responding to pulse steroids x 3d) compared subsequent plasmapheresis- vs IVIG treated patietns and shows similar mortality rates(18.3% vs 19.5%), but apheresis had more stays (45 vs 32 d) & cost ($34k vs $23k) https://t.co/QTnbPzf6Jd https://t.co/EgI2ueIhdz

Registration is still open! Join us at RheumNow Live on 3/18 and 3/19. We have a great agenda lined up including a panel on Rheumatoid Arthritis: Revolutionary Advances in Therapy. https://t.co/duAfKSDi1O https://t.co/JkbHa6b2Fg

NEJM Case: 44 yoF w/ 1wk hx of pustular rash, 1st on face, then legs. Also has ankle pain & odynophagia. PMHx oral ulcers. Exam: Aphthous ulcers & all labs were negative (ANA, ANCA, HIV, RPR, etc). Skin Bx= small-vessel vasculitis. What Dx? https://t.co/gxjXRaRKzq https://t.co/OYmC4om6hi

Study of 21 Downs syndrome pts shows DS to be an autoimmunity-prone state, with a steady-state cytokinopathy, and evidence of hyperactivated CD4 T cells and ongoing activated B cells (CD11c+) - all contribute to a breach in immune tolerance. https://t.co/UUEByfBrqk https://t.co/ekq8AHYlxQ

GCA patients with AORTITIS proven by CTA or FDG-PET/CT have higher rates of relapse. Among 82 GCA pts, 78% positive on both CTA & PET. Relapse was seen in 70% in the CTA+/PET+ group & 29% in the CTA-/PET+ (p = 0.019). https://t.co/psA6hywouL https://t.co/WORiBd9Qli

New PMR Paradigm Lessons from the clinic, brought to you by RheumNow Live. Join us on March 18 &19, 2023 in Dallas, TX https://t.co/4umv0FvmsQ https://t.co/iFQGIHiIds

Does Biologic Treatment in Psoriasis Reduce the Risk of PsA? Retrospective claims analysis shows that psoriasis patients treated with an IL-12/23 inhibitor or an IL-23 inhibitor had a lower risk of developing incident PsA. https://t.co/j73V7zMnkn https://t.co/EhGUXDNNlS