Tweets
NLRP12 is a negative regulator of innate immune activation and type I interferon production. SLE PBMCs have low levels NLRP12 (inverse correl w/ IFNa & Hi Dz activity. NLRP12 knockouts or deficiency Incr autoAbs, inflammation & renal damage https://t.co/PjTQNHhduB https://t.co/m0erNXMkUC
Links:
Dr. John Cush @RheumNow ( View Tweet )
3 years 5 months ago
GRAPPA Recommendations for Treating Enthesitis in PsA
GRAPPA has provided new updates to the mgmt of enthesitis in patients with PsA, affecting at least 30% of PsA patients and is associated with more severe disease, x-ray damage, and poorer outcomes.
https://t.co/AC6KHGMeo0
Links:
Dr. John Cush @RheumNow ( View Tweet )
3 years 5 months ago
New 5 Peptide Autoantibody Panel Complements RA Diagnosis
Antibodies to peptides not currently used for rheumatoid arthritis (RA) diagnosis helped identify patients with untreated early disease that conventional biomarkers missed, researchers said.
https://t.co/twgULvokPY https://t.co/O0I4i81RAN
Links:
Dr. John Cush @RheumNow ( View Tweet )
3 years 5 months ago
Systemic Sclerosis cohort study of 506 SSc pts with saw 5.3 with Degos-like lesions (89% in fingers). Degos lesions more assoc w/ diffuseSSc & acro-osteolysis, digital ulcers, and calcinosis (but not renal crisis, ILD, or pulmonary HTN
https://t.co/Usrfr0XcCJ https://t.co/pmwkHsaJOx
Links:
Dr. John Cush @RheumNow ( View Tweet )
3 years 5 months ago
ChatGPT - A Boom or Threat to Scientific Publication?
ChatGPT is a new, AI chatbot that has dramatically changed the digital worlds of education, research, statistics and more.
Recently there were reports of ChatGPT passing the LSAT, USMLE, and more.
https://t.co/CZd0WjOas5 https://t.co/Nx49SqXoHG
Links:
Dr. John Cush @RheumNow ( View Tweet )
3 years 5 months ago
High- Versus Low-Dose Exercise Therapy for Knee Osteoarthritis
The Annals of Internal medicine has reported the results of high-dose versus low-dose exercise therapy demonstrating no benefits from more intense exercise.
https://t.co/BtqeYWKG34 https://t.co/ngyM1DshDz
Links:
Dr. John Cush @RheumNow ( View Tweet )
3 years 5 months ago
Multicenter study of 80 AOSD & 60 controls used to develop AOSD criteria:
- 3 pts rash
- 3pts fever ≥ 39C
- 2 pts pharyngitis
- 2 pts arthritis
- 2 pts NLR ≥ 4
- 1 pt glycosyl ferritin ≤ 20%
7 pts = Dx (sens 92.5%) vs Yamaguchi(79%), Fautrel (76%) https://t.co/Amew1RHaA1 https://t.co/dnJ6zVyfOW
Links:
Dr. John Cush @RheumNow ( View Tweet )
3 years 5 months ago
Full read, solid review of Diagnosis and management of autoimmune hepatitis from BMJ https://t.co/9OdxHjXMKW https://t.co/1kuHPZBLSE
Links:
Dr. John Cush @RheumNow ( View Tweet )
3 years 5 months ago
Pregnancy & RA: metanalysis of 9 studies, 12K RA pts met vs 10 million controls. RA preg have more maternal complications (C sect OR 1.55; preeclampsia OR, 1.6; preterm OR, 1.8) & neonatal probs (low gestat wt, ICU OR 1.34, & stillbirths OR, 1.99). https://t.co/30WTMC3MKn https://t.co/VXoHesd3iT
Links:
Dr. John Cush @RheumNow ( View Tweet )
3 years 5 months ago
Univ of Toronto’s PsA Study looked at surgery amongst 1574 pts: 185 pts (~12%) had 379 MSK surgeries related to PsA. Signif higher rates of surgery were seen w/ #damaged joints (HR 1.03), TJC/SJC (HR 1.04), nail Dz (2.08), ^ ESR (2.37), B27+ (2.22) https://t.co/XdUJ0guwUh
Links:
Dr. John Cush @RheumNow ( View Tweet )
3 years 5 months ago
Frailty in Vasculitis
Dr. Patricia Harkins sits down with Professor Sebastian Sattui to discuss Abstract 0444, Prevalence of Frailty and Associated Factors in Patients with Vasculitis, being presented on at the ACR22 Convergence.
https://t.co/u0CZuEcyM9 https://t.co/JXEcSoHsA2
Links:
Dr. John Cush @RheumNow ( View Tweet )
3 years 5 months ago
New Guideline: Vaccinations OK With Few Tweaks for Rheum Patients
Nearly all available vaccines can be given to people with rheumatologic diseases, according to a new, detailed guideline from the ACR.
https://t.co/514mIylgzj https://t.co/9Zq9pGcujV
Links:
Dr. John Cush @RheumNow ( View Tweet )
3 years 5 months ago
