Good review of Diagnosis and Treatment of Pulmonary Sarcoidosis in JAMA. - Lung progression (in only 10%) assoc w/ 12-18% 5yr mortality - Sx Sarcoid w/ Lung: start Pred 20 to 40 mg/d for 2 -6 wks - Steroid sparing w/ MTX, AZA or TNFi https://t.co/aVnUXaj0sj https://t.co/JN142hlR6g

Approximately 61% of patients with rheumatoid arthritis or psoriatic arthritis who use methotrexate report side effects following weekly dosing, including fatigue and nausea, according to data published in Rheumatology and Therapy https://t.co/k7hhdbIhW1 https://t.co/GiaihMGnWK

Full read review of advances in bone biology leading to drug development (denosumab, romosuzumab, Burosumab), advances in Pagets and rickets and key regulatory molecules for bone remodeling, RANK, RANKL, OPG, & sclerostin https://t.co/1d6A6MsdbJ https://t.co/IuKEp1PQtr

Best of 2022: The Enthesitis Challenge in Psoriatic Arthritis https://t.co/S7OR6zXTiw https://t.co/Mgy4IcoIZj

JAMA - Update/Review of Hemochromatosis Dx and Rx. - 5 gene defects in hepcidin. 95% HFE & the C282Y variant - 90% are asymptomatic - Suspicion w/ arthralgias, LFTs, hepatomegaly, cardiomyopathy, 1st degr relative - Untreated, 9% risk of cirrhosis https://t.co/LWbIbLITK9 https://t.co/xDpA16K0tm

Hyaluronic Acid Knee Injections Equivalent to Placebo In the United States, where over $300 million is spent annually on intraarticular hyaluronic acid injections, yet another study shows such therapy to be no better than placebo. https://t.co/bBEwpId84L https://t.co/5msGqViTpz

Drug-Induced Lupus from Proton Pump Inhibitors A wide range of therapies have been implicated in causing drug-induced lupus erythematosus (DIL); now it appears that proton pump inhibitors (PPIs) can be added to the list of causative drugs. https://t.co/Jp3oNUhP6c https://t.co/AcC4mM0nLM

Effect of Intraarticular Steroid Shots on Knee OA Outcomes In patients with osteoarthritis of the knee, intra-articular injections of steroids did not increase rates of either disease progression or subsequent knee replacement surgery, researchers said. https://t.co/yqVHPmqzzi https://t.co/k8dMADHg7P

JAMA - Update/Review of Hemochromatosis Dx and Rx. - 5 gene defects in hepcidin. 95% HFE & the C282Y variant - 90%are asymptomatic - Suspicion w/ arthralgias, LFTs, hepatomegaly, cardiomyopathy, 1st degr relative - Untreated, 9% risk of cirrhosis https://t.co/xFTMqkOMSE https://t.co/CmiokvIGvD

Best of 2022: Methotrexate Side Effects https://t.co/ySFyjwYQPX https://t.co/HjlvUzrG9n

#POTS Postural orthostatic tachycardia syndrome - how it might link to other conditions https://t.co/Ekn6KtOrC4 #Fibromyalgia #chronicillness #migraine #hypermobility #EDS https://t.co/JX1WDm2KKn

$520 billion is the estimated cost of physical inactivity from 2020 to 2030 @LancetGH: https://t.co/JynmtU9oCF Of the expected 500 million preventable cases of disease, 43% due to #depression and #anxiety. #MentalHealthMatters @fiona_bull https://t.co/sVjkceNGiq