Tweets
#Vasculitis #ACR22 highlights. #Rituximab more remission in clinical care for GPA - observational, less infections if 600 mg IV fixed q6 mo how long to continue? Abst#1084 and less flares w Rituximab maintenance in the MAINRITSAN studies abst#527 Ritux is new SoC in GPA @RheumNow
Janet Pope @Janetbirdope ( View Tweet )
3 years 8 months ago
Aggarwal @docrota et al. ProDERM results on skin and QoL. Statistically significant improvements in CDASI (both activity and damage) and SF-36. @RheumNow #ACR22 Abstr#2239 https://t.co/vsnvYUla13
Richard Conway @RichardPAConway ( View Tweet )
3 years 8 months ago
Let's review how GCs induce #Osteoporosis 👇(every Rheum should know this!)
💊GCs have bone cell specific effects on:
💠Osteoclasts ⬆️resorption, survival
💠Osteoblasts ⬇️🦴formation & prolif; ⬆️apoptosis
💠Osteocytes ⬆️apoptosis & skeletal fragility
#ACR22 @RheumNow @rheumarhyme https://t.co/n61OXkmRgr
sheila @RHEUMarampa ( View Tweet )
3 years 8 months ago
Espinosa-Ortega et al. Effect of DM ab on damage (as per MDI) over time. Most damage in PM/Scl>seronegative>other abs @RheumNow #ACR22 Abstr#2241 https://t.co/g8xTRyw6NZ https://t.co/sR1tT2QmU3
Richard Conway @RichardPAConway ( View Tweet )
3 years 8 months ago
BKZ resulted in clinically meaningful improvements in FACIT-Fatigue and pain (PtAAP) in approximately half of pts w/ active PsA who are bDMARD-naïve or TNFi-IR. Abs 2119 #ACR22 @RheumNow https://t.co/29gzmMZRlG https://t.co/qziqGNxQih
Dr. Rachel Tate @uptoTate ( View Tweet )
3 years 8 months ago
After 1st TNFi, cycling/swapping strategies both acceptable in PsA w/ similar retention rates. Further studies needed to perform survival subgroup analysis regarding different extra-articular manifestations and PsA subtypes. Abs 2149 #ACR22 @RheumNow https://t.co/SRPhSiGeUI https://t.co/EYDULe52A3
Dr. Rachel Tate @uptoTate ( View Tweet )
3 years 8 months ago
Luedders et al. Higher plasma MMP-7 and MMP-9 assoc development incident RA-ILD in RA patients @RheumNow #ACR22 Abstr#2252 https://t.co/woVErubytC https://t.co/r916r1AxtN
Richard Conway @RichardPAConway ( View Tweet )
3 years 8 months ago
More PsA pts on DEUC vs PBO achieved each of the MDA components at 16 weeks. Abs 2136 #ACR22 @RheumNow https://t.co/OrrDWfvGty https://t.co/CdCQzmgOOO
Dr. Rachel Tate @uptoTate ( View Tweet )
3 years 8 months ago
🌟 COVAX register 🌟
🦠flares of IMRD following covid vax uncommon
👉factors associated with flare:
⬆️disease activity
🙋♀️ female
💊no DMARD @ vax
💊stop/⬇️ DMARD @ vax
👉⬇️ flare assoc with:
💥young
💉RTX
@RheumNow #ACR22 Abst #2274 https://t.co/S892lKcEvS
Patricia Harkins @DrTrishHarkins ( View Tweet )
3 years 8 months ago
Long term RZB provides durable efficacy response in PsA through 100 weeks. No new safety signals. Abs 2145 #ACR22 @RheumNow https://t.co/HfJvS1HzDW https://t.co/T67lDnxeLy
Dr. Rachel Tate @uptoTate ( View Tweet )
3 years 8 months ago
Updated ACR GIOP guidelines:
Panel recommends doing Initial fracture risk assessment using the CLINICAL fracture risk assessment then RE-assessing while pts continue on GCs (👇)
☝️Magic nos. GC>/= 2.5mg/d for >3mos
#ACR22 @RheumNow @rheumarhyme #Osteoporosis https://t.co/7oWqHg8Tdv
sheila @RHEUMarampa ( View Tweet )
3 years 8 months ago
Connolly @CaoilfhionnMD et al. 3 doses SARS-CoV-2 vaccine assoc reduced breakthrough infection in Omicron wave in RMD patients. @RheumNow #ACR22 Abstr#2275 https://t.co/ONXiY8JShK https://t.co/QHNYG9XuJ0
Richard Conway @RichardPAConway ( View Tweet )
3 years 8 months ago
