Tweets
#FMF 2350 pts = 40% with arthritis
- Colchicine resistance in 20%
- M694V mutation carrier rate high (mutant MEFV gene)
- FMF pts with arthritis have a more severe disease course
- incidence of spondyloarthropathy was increased in FMF
#ACR22 @RheumNow abst#1830 https://t.co/uiLhjK0UjY
Bella Mehta @bella_mehta ( View Tweet )
3 years 8 months ago
Rohmer @TerrierBen et al. 196 cases of PAN from France. 28% assoc another condition - MDS and cancer mainly. Relapse in 39% - assoc age>65, GI, skin necrosis. Death assoc age>65, AKI, secondary PAN, necrotic purpura. @RheumNow #ACR22 Abstr#2232 https://t.co/fyJY9O3Gm7
Richard Conway @RichardPAConway ( View Tweet )
3 years 8 months ago
Tonight! Join our RA Topic Panel with panelists: Drs. Richard Conway, Aurelie Najm, David Liew, Janet Pope, Julian Segan
@RichardPAConway @AurelieRheumo @drdavidliew @Janetbirdope @JulianSegan #ACR22
https://t.co/j13W4GM56w https://t.co/fgDwPVdskC
Links:
Dr. John Cush @RheumNow ( View Tweet )
3 years 8 months ago
RheumNow’s expanded coverage of the #ACR22 Annual meeting is sponsored in part by Novartis. All content chosen by RheumNow & its Faculty.
Dr. John Cush @RheumNow ( View Tweet )
3 years 8 months ago
Curtis et al. Primary non-adherence to csDMARDs and b/tsDMARDs in RA/PsA/SpA. Medicare and commerically-insured patients. 20-44%! of new prescriptions not filled by 6 months. Higher for csDMARDs than b/tsDMARDs @RheumNow #ACR22 Abstr#2199 https://t.co/Pwg6GKu7Gg https://t.co/wPF0pu1UDa
Richard Conway @RichardPAConway ( View Tweet )
3 years 8 months ago
Abstr #2192 risk of serious infxn in newborns of mothers on TNFi by placental transfer
- % serious infection in TNFi in high vs low placental transfer (2.1% vs 1.6%)
- HR (high vs low) 0.98 (95% CI 0.36-2.61)
- No significant difference in risk of serious infxn
@RheumNow #ACR22 https://t.co/7Lfpf7PERu
Akhil Sood MD @AkhilSoodMD ( View Tweet )
3 years 8 months ago
Which patients with IIM are high risk for #cancer?
Abstract #0002 #ACR22 @RheumNow #ACRBest
📍Dermatomyositis
📍Anti-TIF-gamma, anti-NXP2
📍Age > 40y at dz onset
📍Dysphagia
📍Cutaneous necrosis
📍Persistent high dz despite immunosuppressive tx
Catherine Sims, MD @DrCassySims ( View Tweet )
3 years 8 months ago
Which is better for CV risk in RA:
triple therapy DMARDs or TNFi?
TARGET study
n=159 using PET/CT surrogate (endpoint responsiveness👀)
- either led to benefit
- both equally good
- benefit *not* linked to change in DAS28
A direct CV effect of RA Rx?
ABST2215 #ACR22 @RheumNow https://t.co/4FPvSbfGsD
David Liew @drdavidliew ( View Tweet )
3 years 8 months ago
Vaccination +/- prior Covid-19, and with either mRNA or vectored DNA vaccines were not associated with AIRD flares. Negative association 21-days after 1st Covid-19 vaccination and no association after 2nd or 3rd doses. Nakafero G Abs#2194 https://t.co/vA8cMNQGkr #ACR22 @RheumNow https://t.co/SZnXejnmYt
Dr. Antoni Chan @synovialjoints ( View Tweet )
3 years 8 months ago
Singh @NamrataRheum et al. Frailty in patients treated bDMARD/tsDMARD assoc serious infections aHR 1.34, any infection aHR 1.18, hospitalisation aHR 1.34 (all relative non-frail). @RheumNow #ACR22 Abstr#2218 https://t.co/ONsTBq8ehB https://t.co/iTVANh5flk
Richard Conway @RichardPAConway ( View Tweet )
3 years 8 months ago
Thieves Market #ACR22
Ulcerative palatal lesions, non-spec bx
+ANA 1:320 w other neg Abs
Empiric steroids for presumed vasculitis
New cavitary lung lesion. Pathology showed vasculitis
Dacrocystitis w lobulated paranasal mass
Dx: Extra nodal NK/T-cell lymphoma
Fatal case
@RheumNow https://t.co/TlDy9GfW7N
Eric Dein @ericdeinmd ( View Tweet )
3 years 8 months ago
Flatman et al. Risk of infections in children with third trimester TNFi use, high vs low (CTZ, ETN) placental transfer. No difference but wide CIs, aHR 0.98 (0.36, 2.61) @RheumNow #ACR22 Abstr#2192 https://t.co/350UxX9bkL https://t.co/29uOtek8w7
Richard Conway @RichardPAConway ( View Tweet )
3 years 8 months ago
