Tweets
800+ women w/ IMID & 1700+ ctrl w/ 6 yrs follow-up
All GC users < BMD levels
-4.2% > 2.5mg/d
-2.7% <2.5mg/d
Crude FX rate 4.8/100PY GC >= 5mg/d, 2.5/100PY GC < 2.5mg/d
🦴Fx incidence > IMID vs. Ctrls
GC use >= 5mg/d x2 risk of Fx
https://t.co/6sj77PwyYQ
Abs#L01 #ACR22 @Rheumnow https://t.co/OZhfuh0Jrm
Aurelie Najm @AurelieRheumo ( View Tweet )
3 years 8 months ago
14M111 Updated ACR Guidelines for Glucocorticoid-Induced Osteoporosis #ACR22 🦴🦴
Reminder: Recalculate FRAX scores with scaling for prednisone equivalent dosing!
Use other clinical fracture risk assessments
@RheumNow https://t.co/qZDlb1Cij7
Eric Dein @ericdeinmd ( View Tweet )
3 years 8 months ago
Dr. B Humphrey #ACR22 #Osteoporosis Guidelines:
FRAX needs to be adjusted according to the dose of GC's (7.5+ mg/day multiply FRAX score by 1.2)
#ACR22 @rheumnow https://t.co/U7IOjbTwxN
TheDaoIndex @KDAO2011 ( View Tweet )
3 years 8 months ago
#L01 #acr22 @rheumnow chronic GC use in rheum Dx assoctd w/⬇️ T scores & ⬆️fracture even if dose 2.5 mg or less. GC use ≥5 mg/day associated w/ 2-fold higher risk of fracture of any kind compared to all other doses& controls (aHR 2.37, 95% CI 1.33-4.23).Preventable w/anti-OP Rx https://t.co/sCWkEBPMMT
Olga Petryna @DrPetryna ( View Tweet )
3 years 8 months ago
Almayali et al. Follow-up of GLORIA study. Now tapering of the pred 5mg after 2 years. Small increase in disease activity (to same level as prev placebo), numerical increase in flare. No adrenal insufficiency @RheumNow #ACR22 Abstr#2000 https://t.co/5oclSdlXWA https://t.co/HT2pmsxPiC
Richard Conway @RichardPAConway ( View Tweet )
3 years 8 months ago
Wow! Walrabenstein et al. RCT of plant-based diet (and exercise and stress management) vs usual care in low-moderate disease activity RA. It worked! But which of the 3 parts of the intervention was responsible? @RheumNow #ACR22 Abstr#1998 https://t.co/X1f07ZWPjU https://t.co/nkM4misfFW
Richard Conway @RichardPAConway ( View Tweet )
3 years 8 months ago
Yokose et al. Higher risk of mortality in women with gout. Primarily CVD related death. @RheumNow #ACR22 Abstr#1757 https://t.co/Ft3Km8Jw17 https://t.co/uBOUnV4n0Z
Richard Conway @RichardPAConway ( View Tweet )
3 years 8 months ago
Haibel et al. Intraarticular morphine no different to placebo and inferior to steroid in knee OA. @RheumNow #ACR22 Abstr#1833 https://t.co/9dOlfYMVlj https://t.co/a3uvw3gVw3
Richard Conway @RichardPAConway ( View Tweet )
3 years 8 months ago
Kivitz et al. Phase 2 RCT Dazodalibep (non-antibody biologic antagonist of CD40L) in csDMARD/bDMARD-IR RA. Improve DAS28-CRP, CDAI, SDAI, TJC, SJC at day 113. @RheumNow #ACR22 Abstr#2008 https://t.co/RwRbeFC4rt https://t.co/F8bEI1lZGM
Richard Conway @RichardPAConway ( View Tweet )
3 years 8 months ago
L09 #ACR22 MTX in Post-Roe Era
6% patients reported barrier to MTX access
1 pt noted restriction to HCQ
Most delays due to pharmacy - told due to pregnancy/abortion concerns or unexplained reason
Rare BUT Real Problem - shows importance of @ACRheumDC advocacy efforts
@RheumNow https://t.co/8Yr7nynzN6
Eric Dein @ericdeinmd ( View Tweet )
3 years 8 months ago
L10 #ACR22 Efgartigimod in IMNM
IgG1 Fc fragment targeting neonatal Fc receptor (FcRn)
Restored grip and muscle strength in mice studies with pathogenic anti-HMGCR+ (p<0.05)
Total IgG and anti-HMGCR Ab became undetectable
@RheumNow
Eric Dein @ericdeinmd ( View Tweet )
3 years 8 months ago
Hayashi et al. No effect of colchicine prophylaxis (vs NSAID or vs no prophylaxis) on MACE in re-analysis of CARES trial. @RheumNow #ACR22 Abstr#1809 https://t.co/I6evAl4BLd https://t.co/n70FvYah1p
Richard Conway @RichardPAConway ( View Tweet )
3 years 8 months ago


