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Ab2126 #ACR22 Risankizumab on Enthesitis/Dactylitis KEEPsAKE 1&2 - RZB v PBO 1407 pts -baseline 63% enth, 28% dact, 20% both Wk 24: 14% decr. enthesitis, 17% decr dact, 13% decr both Mean time to resolution decreased Results maintained through wk 52 @RheumNow https://t.co/RBubeuJoh8
Eric Dein @ericdeinmd ( View Tweet )
3 years 8 months ago
Frey @CaoilfhionnMD @JuliePaikMD et al. Increasing duration of hold of MMF (esp >=10 days) increased response to SARS-CoV-2 vaccine. No difference in disease flare rates. @RheumNow #ACR22 Abstr#0797 https://t.co/5nxo2nLg80 https://t.co/sx1Roxngx9
Richard Conway @RichardPAConway ( View Tweet )
3 years 8 months ago
In this prospective cohort study by Dr Jacquez, there was a statistically significant inverse assoc bet. average yearly HCQ dose and overall damage accrual 👇 Reassuring data. ☝️HCQ consistently proves to be a beneficial drug for #lupus #ACR22 @Rheumnow ABST#0982 @rheumarhyme https://t.co/nWHS9JtEsH
3 years 8 months ago
Pedersen @EBRheum et al. 203 RCTs, 35 (17.2%) remained unpublished more than 30 months after completion. Cited reasons: ongoing preparation/review of paper (50%), sponsor/funder problems (40%), unimportant/negative result (20%).@RheumNow #ACR22 Abstr#0827 https://t.co/V2a48iiAcn https://t.co/FLqQhjvlOx
Richard Conway @RichardPAConway ( View Tweet )
3 years 8 months ago
#ACR22 Abstr#0825 Can we identify predictors of deaths in patients presenting with Macrophage Activation Syndrome? A cohort study (N=43) reported MAS was mostly secondary to disease. 10/43 died. Super high Ferritin and raised Ferritin/CRP ratio were assoc with deaths @RheumNow https://t.co/JCH30pi4Vf
Md Yuzaiful Md Yusof @Yuz6Yusof ( View Tweet )
3 years 8 months ago
Boekel et al. Omicron variant assoc lower risk of severe COVID-19 in rheumatic disease than prior variants EXCEPT rituximab treated patients. @RheumNow #ACR22 Abstr#0705 https://t.co/57Boj4SEt5 https://t.co/d2NoX83y5l
Richard Conway @RichardPAConway ( View Tweet )
3 years 8 months ago
Mendel et al. Use of TMP-SMX prophylaxis in GPA from MarketScan and Medicaid. Used in <25% treated with RTX!? Female sex negatively assoc (OR 0.61)!? Steroid use in month prior associated (OR 4.31) @RheumNow #ACR22 Abstr#1071 https://t.co/56a0nHR8o4 https://t.co/5LygdFMrss
Richard Conway @RichardPAConway ( View Tweet )
3 years 8 months ago
Kifayat et al. Response to Shingrix in rheumatic disease patients. 3/3 PsA, 5/6 SLE, 2/14 RA pts reached protective level of 150U/ml. IgG titres and SI are 3x lower compared to non-rheumatic patients. @RheumNow #ACR22 Abstr#0800 https://t.co/Gm7ldxK5xd https://t.co/BlHuU2Jxk2
Richard Conway @RichardPAConway ( View Tweet )
3 years 8 months ago
I was schooled for exams, testing fine motor function with a buttonhole: felt contrived. Imagine an electrical glove for RA pts, doing functional assessment properly Italian study: engineered glove data + HAQ correlates with DAS28 Consistent/scalable! ABST0904 #ACR22 @RheumNow https://t.co/4ZR0An5N9j
David Liew @drdavidliew ( View Tweet )
3 years 8 months ago
Martínez-López et al. Higher rates of elevated transaminases with DMARD in those who previously had abnormal transaminases with isoniazid. @RheumNow #ACR22 Abstr#0816 https://t.co/xiL6DPPcw3 https://t.co/jjxRoEr8iM
Richard Conway @RichardPAConway ( View Tweet )
3 years 8 months ago
Khidir et al. Lower educational level increases risk of progression of clinical suspect arthralgia to inflammatory arthritis. HR 2.35 and 5.72 in 2 cohorts. not explained by smoking, BMI or a delay in seeking medical care @RheumNow #ACR22 Abstr#0704 https://t.co/B4bm2Ihapx https://t.co/Veks0WpHLR
Richard Conway @RichardPAConway ( View Tweet )
3 years 8 months ago
Ab1042 #ACR22 Ixekizumab Long-term Safety A Deodhar: Pooled 25 studies for PsO, PsA, AS 5.4 pooled AE per 100-patient/year 0.5 IBD per 100-PY 1.3 Oral candidiasis per 100-PY Re-assuring safety numbers. Deodhar: "These are numbers to use in clinical practice" @RheumNow

Eric Dein @ericdeinmd ( View Tweet )

3 years 8 months ago
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