Jack-The diagnosis of TA is further complicated when patients have an established Dx of RA which may be flaring. PMR like symptoms and headache complaints as well as elevated ESR are somewhat non-specific and non-diagnostic. A recent TAB on the affected side of my patient was negative. When patients have OP, DM2 or other comorbidities including advanced age, blasting ahead with high dose prednisone can be problematic.