Artie- couldn’t agree more- laboratory tests must be subjected to. Baysean reasoning as you note- the myositis panel is an excellent example where bye and large should be reserved to be ordered after myositis has been diagnosed or at least highly suspected (hi pretest probability ) where it can then provide data that allows clinical subset, identification which can have profound implications for prognosis and management. ( probability of malignancy, ILD, treatment, selection, etc..). Well said.
Lenny