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“These drugs aren’t going anywhere because they are literally curing cancer.” - Dr. Susan Manzi on checkpoint inhibitors and autoimmune adverse events. Check out the poster hall to see all the emerging immune related AEs. #ACR19 @RheumNow
Maeve Gamble MaeveGamble ( View Tweet)
ACOG recommends low dose ASA for all pregnant women with lupus. But we’re not doing well...in a multi-national SLE cohort of 475 pts, only 25% were exposed to ASA. #ACR19 @RheumNow #lupus
Maeve Gamble MaeveGamble ( View Tweet)
Abstr#808 Pt2 of GiACTA:
*42% of pts in remission and on no tx after 1 yr of wkly TCZ maintained tx free remission for 2 more yrs
*GCSs over 3yrs lower in pts originally assigned TCZ
*For flares, reinitiating TCZ restored remission
*No new safety signals
#ACR19 @RheumNow #GCA
Maeve Gamble MaeveGamble ( View Tweet)
What do you do with residual fatigue in well controlled RA? #ACR @RheumNow Abstr#461now
Janet Pope Janetbirdope ( View Tweet)
Fatigue is a big deal for pts with ERA but if rapid remission by 3 months fatigue improvement is better and differences persist for 5 years but mean fatigue is not normal #ACR19 @RheumNow abstr#461 https://t.co/hDbPmCql1m
Janet Pope Janetbirdope ( View Tweet)
I didn’t realize how fast Pegloticase works.
Assuming the urate burden of a gout patient, Pegloticase can degrade all the urate in the body over 5-40 days!
#ACR19 @rheumnow 3S050 Lipsky
Dr Irwin Lim _connectedcare ( View Tweet)
Evidence based non-pharm therapy #ACR19 #fibromyalgia @RheumNow FM MTP Clauw https://t.co/ZhGLsqg0Tb
Philip Robinson philipcrobinson ( View Tweet)
Mean time to total resolution of all tophi was 9.9 months on Pegloticase
- velocity of resolution was very heterogenous
#ACR19 @rheumnow 3S050
Dr Irwin Lim _connectedcare ( View Tweet)
Dr. Weinblatt’s vaccine review slide. @RheumNow #ACRbest #ACR19 https://t.co/rKShBbdk7z
Dr. Rachel Tate uptoTate ( View Tweet)
Pneumonia vaccination update! #ACR19 @RheumNow https://t.co/yJVg4wt90S
Dr. Rachel Tate uptoTate ( View Tweet)
Reductions in mean arterial pressure, systolic & diastolic BP in responders to biweekly Pegloticase
Not associated with any changes in renal function. Independent of any effect XaNthine Oxidase
#ACR19 @rheumnow 3S050
Dr Irwin Lim _connectedcare ( View Tweet)
Prednisone at 5mg po daily for over three months is a FRAX risk factor we need to remember. Knowledge bowl pearls. @RheumNow #ACR19
Dr. Rachel Tate uptoTate ( View Tweet)
Uveitis is associated with bisphosphonates. Calcium citrate is useful in pts with history of renal calculi. Knowledge bowl pearls. #ACR19 @RheumNow
Dr. Rachel Tate uptoTate ( View Tweet)
Almost all patients with pain have mixed pain states, so working out effective therapies for their pain depends on the proportion of each type of pain they have: nociceptive/neuropathic/centralised pain #ACR19 FM MTP Prof Clauw @RheumNow
Philip Robinson philipcrobinson ( View Tweet)
Bechterew’s disease is an eponym for AS. #ACR19 @RheumNow knowledge bowl!
Dr. Rachel Tate uptoTate ( View Tweet)
Benjamin Franklin had PsO which may have predisposed him to gout. Hippocrates is credited with the first description of scleroderma!pearls from Knowledge Bowl preliminaries. #ACR19 @RheumNow
Dr. Rachel Tate uptoTate ( View Tweet)
Dr Robert Terkeltaub gives a great presentation summarizing the mechanistic complexity of hyperuricemia and gout. A one slide summary shows us the many aspects of disease.
#gout #uricacid #hyperuricemia #ACR2019
@RheumNow https://t.co/qnGV71OvD4
Gout Study Group GoutGroup ( View Tweet)
Looks like the numbers are in. Last year’s great debate with Dr Petri who argued to keep HCQ 6.5mg/kg/d in SLE lost out to what rheums do in clinical practice @rheumnow
k dao KDAO2011 ( View Tweet)
@ACR19 @rheumnow #ACRBest Abstr#L01:Risk for hosp serious infx (SIE) in PsO/PsA from multi-databse cohort (n=123,383) w/TNFi/IL17i/IL12-23i/or apremilast
1. Highest risk w/Infliximb
2. Lowest risk w/Ixekizmb & ustekmb
3. Ustekmb had lowest risk even when compared to apremilast
k dao KDAO2011 ( View Tweet)
Advice from Dan Clauw on using cannabinoids / CBD for pain. Chronic pain users should aim for 10:1 CBD:THC ratio #ACR19 @RheumNow MTP https://t.co/DHssq7jmlS
Philip Robinson philipcrobinson ( View Tweet)