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#EULAR2020 - it's been a blast!
Thanks as always for everyone following the meeting on Twitter - the conversation on here has made the meeting for me!
It's been lots of fun covering the meeting for @RheumNow - look out for some videos out on https://t.co/j0ZwZujGBj next week 🙂 https://t.co/0bdQKsuoND
Links:
David Liew drdavidliew ( View Tweet)
Your #RA patients in low disease or remission, do you maintain, reduce or stop DMARDs #EULAR2020
Dr. John Cush RheumNow ( View Tweet)
#EULAR2020 Updated RA Mgmt Recc
Main points:
1. MTX 1st line (if contraind, then SSZ/LEF; NOT HCQ)
2. Add bDMARD/JAKi if 1st csDMARD doesn't work + poor Px
3. Use IL-6i or JAKi for pts who can only take monoRx and failed csDMARD
@RheumNow
https://t.co/AIXz2dEOrX
k dao KDAO2011 ( View Tweet)
Study in Norway reveals that the majority of the women w/ SpA were not treated with TNF inhibitors before or during pregnancy. Few on TNFi were continued on tx during pregnancy. #EULAR2020 @RheumNow https://t.co/t7B6pASeWQ https://t.co/BwU6RF5Qkn
Links:
Dr. Rachel Tate uptoTate ( View Tweet)
Sustained clinical response shown over the 10 yrs of this German study in r-axSpA and nr-axSpA pts treated with ETN. No new safety signals. Abstract #AB0660 #EULAR2020 @RheumNow https://t.co/KCMDyzHaSr https://t.co/yFSTgWqzBQ
Links:
Dr. Rachel Tate uptoTate ( View Tweet)
Switching TNFi to VDZ in pts IBD-related SpA associated w/ articular exacerbation of SpA in 1 out of 4 patients within the first 5 months. New-onset MEM is also observed in up to 15% of patients with IBD treated with VDZ. #EULAR2020 @RheumNow https://t.co/ZVjZC7hvxs https://t.co/d1RT3GzB2b
Links:
Dr. Rachel Tate uptoTate ( View Tweet)
Study of the French registries for TCZ, RTX, ABA, compared the risk of GI perforations (GIP). GIP risk was higher with TCZ (vs RTX,ABA) but was largely due to TCZ increasing the risk of diverticulitis. #EULAR2020 #OP0022 https://t.co/MGGWiVh5Jv https://t.co/nC2NblYnGO
Links:
Dr. John Cush RheumNow ( View Tweet)
When starting IV Pegloticase in #Gout, Do you start a DMARD too? #EULAR2020
Dr. John Cush RheumNow ( View Tweet)
#EULAR2020 Recc for irAEs w/ICI:
1. GC's ok, goal<10 mg/d, any csDMARD, bDMARD (TNFi/IL-6),🚫ABT xcept life-threatening myositis
2. Myositis beware bulbar signs: dysphagia, dysarthria, dysphonia: stop ICIs,⬆️GC, IVIG/PE
3. Don't test autoAbs b/f ICI Rx
https://t.co/P5jDgnjK94
k dao KDAO2011 ( View Tweet)
Can you classify SLE by labs only but should you? Serology is part of criteria but why dx with only +ANA, +antiDNA and no other CTD characteristics. Would need cytopenias & RBC casts to think of lab dx of SLE OP0094 @LupusCanada @RheumNow @eular_org #EULAR2020 @CRASCRRheum https://t.co/Jr6SRr3HR1
Janet Pope Janetbirdope ( View Tweet)
My brush with COVID- heart-breaking and inspirational. A story about Larry and Jessica. https://t.co/zZTmwcmRe0
Links:
Dr. John Cush RheumNow ( View Tweet)
Avacopan is as effective as steroids in ANCA Assoc Vasculitis – 330 pt RCT AAV Rx w/ RTX or CTX but randomized to prednisone or avacopan (C5aR antagonist). Avacopan=prednisone remission rates same (72% vs 70%) wk 26 & wk 52 (66% vs 55%). #EULAR2020 #OP0011 https://t.co/WIXJCYkxSb
Links:
Dr. John Cush RheumNow ( View Tweet)
OU=Oral Ulcers https://t.co/1LPye7ohM1
Dr. John Cush RheumNow ( View Tweet)
Do not be tempted to stop MTX or other DMARDs perioperatively! They probably help rather than harm #EULAR2020 https://t.co/jb4ZuZlqSu
Christos Koutsianas Dr_C_Koutsianas ( View Tweet)
RA pt not responding to a 1st biologic; what you predict in a Head to Head - Abatacept vs Upadacitinib?
Dr. John Cush RheumNow ( View Tweet)
#EULAR2020 #op0225 sub study of OPAL Balance: withdrawal of MTxdoes not negatively impact Tofa efficacy in PsA. At 6 mo deltaPASDAS 0.229 (0.079) for tofa mono & 0.q138 (0.081) for tofa+mtx. LFT elevation more common in combination arm @RheumNow https://t.co/NO1agViScD
Olga Petryna DrPetryna ( View Tweet)
#EULAR2020 #fri0505 Still’s pts who are able to achieve remissions w/longer itnervals btw tocilizumab infusions & lower dose of prednisone more likely to successfully withdraw Toci. Time to symptom recurrence in relapse group 7.8 mo. Older pts more likely to relapse @RheumNow
Olga Petryna DrPetryna ( View Tweet)
OU=Oral Ulcers https://t.co/1LPye7ohM1
Dr. John Cush RheumNow ( View Tweet)
Main factors influencing #physicalactivity in inflammatory #arthritis patients are psychological
➡️Main factor related to knowledge of benefits of #exercise & symptoms
➡️Modifiable
➡️Health professional support key
FRI0642-HPR #EULAR2020
👉🏽https://t.co/Vdc7rjnC6Y
by @DavergneT https://t.co/aMUHA5IMrn
Dr Ai Lyn Tan DrAiLynTan ( View Tweet)
@Janetbirdope @eular_org @RheumNow @CRASCRRheum @earlyarthritis Good question. I suspect it may be a class effect but would be good to see H2H btw JAKs one day. If selective JAK 1 inhibition provides more, less or same efficacy is still not clear to me
Olga Petryna DrPetryna ( View Tweet)
