All News

RA, hands, MCP, deformity

Trends in Rheumatoid Arthritis Disabililty, Despite Biologics

d MedPage Today

Disability claims in the U.S. related to rheumatoid arthritis (RA) were just as common in 2015 as in 1999, a government researcher found, against expectations that the advent of biologic therapy would have led to a steady decrease.

Read Article
Rheumatologic diagnosis through hand exam by Dr. Sarah Chung @ACPinternists #rheumatology #rheumtwitter #MedEd #rheumatoidarthritis #BJHM #Hospitalmedicine #IM2022 #MedTwitter 👇🏽 https://t.co/qR4zNa4NcX
Brown Journal of Hospital Medicine BrownJHM ( View Tweet)
Leflunomide responses in #RA assoc w/ high metabolite levels (A77 1726). In 115 LEF Rx Pts, 40% had LDAS/remission. A77 1726 levels neg correlation w/ DAS28-ESR (r = − 0.42, p < 0.001). Levels >10µg/mL & LDAS PPV 70%; NPV 93% https://t.co/V32wUGVWLM https://t.co/L9DwZBwet9

Links:

Dr. John Cush RheumNow ( View Tweet)
Study of 33 #RA pts finds nearly half had peripheral neuropathy (48.5%); sensorimotor in 64.7%, motor in 17.6%. Neuropathy was NOT associated with age, gender, disease activity, functionality, or falls https://t.co/r2aQI2cm27 https://t.co/OOQlWkCAft

Links:

Dr. John Cush RheumNow ( View Tweet)
RheumNow Podcast square

$30 Billion and Counting (4.29.2022)

d Jack Cush, MD

Dr. Jack Cush reviews the news and journal reports and takes viewer questions this week.

Read Article
Systematic literature review of studies where steroids were used as initial "Bridge Therapy" in RA patients - included 10 studies, but only 4 RCTs w/ protocolized discontinuation - these showed 22% were still on GC @ 12 mos, 10% @24 mos https://t.co/aRLhptAASe https://t.co/lg4msIyQfc

Links:

Dr. John Cush RheumNow ( View Tweet)
JIA.oligoarticular.jpg

Biologics for JIA? Not So Fast, Say Insurers

d MedPage Today

It's not a simple matter to prescribe tumor necrosis factor (TNF) inhibitors for patients with juvenile idiopathic arthritis (JIA), at least those with insurance, a single-center study found.

Read Article
Liver,hepatic,red

Arthritis Predicts Hepatic Fibrosis in Hemochromatosis

d Jack Cush, MD

Mayo Clinic Proceedings reports the results of a retrospective, cross-sectional of patients with HFE hemochromatosis showing that advanced hepatic fibrosis is primarily seen in those with arthritis due to HFE hemochromatosis. 

Read Article
COVID-19 Vaccination Uptake and Perceptions in Rheumatic Patients Putman et al has reported vaccine survey results from the C19-GRA in Lancet Rheumatology showing the uptake and vaccine hesitancy among people with rheumatic diseases (RMD). https://t.co/sqsOHGThzV https://t.co/zeZrlDeQ9Z

Links:

Dr. John Cush RheumNow ( View Tweet)
Open label, RCT compared triple DMARD Rx adding either LEF (MLH) or SSZ (MSH) to MTX+HCQ in 136 RA pts. Both were equally effective (non-inferior), 61.7% & 64.7% patients (p = 0.8) at wk 24. AE were also equal (15 vs 21 AE). https://t.co/ZucrYKuNms

Links:

Dr. John Cush RheumNow ( View Tweet)

vaccine,mRNA,Covid,vial

COVID-19 Vaccination Uptake and Perceptions in Rheumatic Patients

d Jack Cush, MD

Putman et al has reported vaccine survey results from the COVID-19 Global Rheumatology Alliance (C19-GRA) in Lancet Rheumatology showing the uptake and vaccine hesitancy among people with rheumatic diseases (RMD).

Survey data from 7005 vaccinated and unvaccinated, adult RMD respondents from 102 countries was analyzed.

Read Article
COVID,vaccinate,injection,green

Evusheld as Protective Therapy in High Risk COVID-19 Patients

d Jack Cush, MD

A single dose of the monoclonal-antibody AZD7442 (combination of tixagevimab and cilgavimab) has been shown to be safe and effective as prophylaxis against COVID-19 infection in high risk individuals who tested positive for COVID-19. 

Read Article
Beijing #RA Cohort study compared 102 T2T (CENTRA) vs 271 usual care pt (TARRA) groups for SDAI outcomes at 12 mos. CENTRA had signif lower SDAI than TARRA (2.1 vs 3.4; p<0.001) & more SDAI-defined remission (71% vs 49%; p<0.001) https://t.co/1JBP33eifI https://t.co/RmGny30QAq

Links:

Dr. John Cush RheumNow ( View Tweet)
Open label, RCT compared triple DMARD Rx adding either LEF (MLH) or SSZ (MSH) to MTX+HCQ in 136 RA pts. Both were equally effective (non-inferior), 61.7% & 64.7% patients (p = 0.8) at wk 24. AE were also equal (15 vs 21 AE). https://t.co/cxdeBfo6XA

Links:

Dr. John Cush RheumNow ( View Tweet)

RheumNow Podcast square

Male vs. Female Responders (4.15.2022)

d Jack Cush, MD

Dr. Jack Cush reviews the news and journal Reports from the past week on RheumNow.com - including fellowship COVID-19 concerns, the limits of T2T in gout and the real odds of RA remission with your first biologic. 

Read Article
Downward Effects! Real world data from 22,934 UK #RA pts starting 1st b/tsDMARD shows DAS remission/LDA achieved in 17% following 1st line, 13% 2nd, & 8-13% with 3rd thru 6th DMARD. (LDA in 29% 1st line, 23% 2nd, 17–22% 3rd thru 6th) https://t.co/cZt0BvhK6I https://t.co/blemgbDoN8

Links:

Dr. John Cush RheumNow ( View Tweet)
dementia,brain

Is Alzheimer's Risk Lower With TNF Inhibitors?

d MedPage Today

Tumor necrosis factor (TNF) inhibitors for rheumatoid arthritis were linked with a lower risk of Alzheimer's disease and related dementia, but only in people with cardiovascular disease, data from the DREAM (Drug Repurposing for Effective Alzheimer's Medicines) study showed.

Read Article
ICYMI: 520 RA pts were screened with FibroScan (liver fibrosis)- F3 or F4 liver fibrosis seen 13.3% of controls vs 12.7% arthritis pts. MTX was not significantly correlated w/ higher FS scores. Liver stiffness was correlated w/ BMI, waist, male , age. https://t.co/PxrabHROPy https://t.co/UAw51Hb5vU

Links:

Dr. John Cush RheumNow ( View Tweet)
RheumNow Podcast square

RheumNow Podcast – What You Do For & What You Do To the Patient (4.8.2022)

d Jack Cush, MD

Dr. Jack Cush reviews the news and journal articles from the past week and discusses the use of fibroscan in RA, steroid hip injections in OA and famous quotes from a famous cardiologist.

Read Article
211 pts presenting w/ hot swollen joint to the ER; 28 w/ septic arthritis; pseudogout 32; gout 50; & others: 101. Predictors of Septic Arthritis: RA (OR 3.4); skin infx (OR 3.3); liver Dz (OR 9.9); knee involv (OR 3.5); immunosuppressive use (OR 3.5) https://t.co/uASovNVOWb https://t.co/Fq3obVDavm

Links:

Dr. John Cush RheumNow ( View Tweet)

Do you get our email newsletter?

Looking for the latest rheumatology news & trends? Sign up for the RheumNow weekday newsletter:

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Rheumnow.com is a news source dedicated to the field of Rheumatology. It is written by experts in the field, and written for rheumatologists and individuals working in related fields. Rheumnow.com provides daily updates on the site and in your inbox when you are signed up for our newsletter.

Copyright {{ 'now'|date('Y') }} All Rights Reserved.