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Limited Impact of Vitamin D Supplementation

d Jack Cush, MD

A systematic review of 81 studies on vitamin D concludes that vitamin D supplementation does not prevent fractures or falls, or have clinically meaningful effects on bone mineral density.

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Filgotinib in Psoriatic Arthritis and Ankylosing Spondylitis

d Jack Cush, MD

Another, new Janus kinase 1 (JAK1) inhibitor is out with impressive data - this time its filgotinib, demonstrating its efficacy and safety two separate clinical trials of patients with psoriatic arthritis or ankylosing spondylitis.

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RheumNow Podcast – To Needle or Not to Needle (11.30.18)

d Jack Cush, MD

Dr. Jack Cush updates the news and reports from the past week at RheumNow.com:

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Rheumatoid Lung Disease Imposes Significant Morbidity and Mortality

d Jack Cush, MD

Insurance claims data were analyzed for the frequency of interstitial lung disease (ILD) associated with rheumatoid arthritis (RA) and finds that although rare, its frequency increased over time and it is associated with a significant mortality rate. 

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Depression worsens back pain; increases healthcare costs. Medicare claims study 73,000 found 6,739 with back pain & 20% of these (1310) had depression. Annual healthcare costs substantially higher in LBP pts w/ depression ($13,153 vs $7,477, P < 0.001). https://t.co/rHqfWPTV7r

Links:

Dr. John Cush RheumNow ( View Tweet)

CDC reports that 40-47% of adults have had a flu vaccination in the past 12 months (higher in elderly (67%). https://t.co/RPmkTECeF7

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Dr. John Cush RheumNow ( View Tweet)

Bisphosphonate safety review — risk of Atypical Femoral Fracture is 1/1000 and risk of osteonecrosis of the jaw is 1/10,000. One-third of IV zolendronic acid pts will have arthralgia/myalgias or flu like sxs. https://t.co/80xBkZlKgn

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Dr. John Cush RheumNow ( View Tweet)

FDA has approved Genentechs ACTpen - a tocilizumab autoinjector 162 mg sc for use in RA, GCA, poly and systemic JIA - should be available in January 2019. https://t.co/YzFHyYxQlS

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Dr. John Cush RheumNow ( View Tweet)

Study of 2053 RA patients from VA medical centers found 27% with chronic lung disease that confered a 51% increased mortality risk; sadly this was not altered by MTX or biologic therapy. https://t.co/nYFnScSXQ4

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Dr. John Cush RheumNow ( View Tweet)

I prefer more slides with less data per slide rather than fewer slides jam packed with multiple miniscule figures #ASH18

John P. Leonard, MD JohnPLeonardMD ( View Tweet)

We are not only doctors for the elderly. Many of our patients are young or even children. Sometimes we treat banal conditions but also we manage severe & autoimmune disorders with systemic involvement. We use innovative therapies. Didn't you know us? We are the Rheumatologists

Emilio Martin Mola emartinmola ( View Tweet)

This is a great conference! https://t.co/GEDlj44jLE

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Dr. John Cush RheumNow ( View Tweet)

2017 US life expectancy decreased for the 3rd year in a row. Drug overdoses & suicides lead the trend, resulting in earlier deaths and how long people live. Life expectancy dropped 78.7 yrs in 2016 to 78.6 yrs in 2017, with changes in men; not women https://t.co/gUParIkR6W

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Dr. John Cush RheumNow ( View Tweet)

Dont Miss the Next Best Meeting in Rheumatology - RHEUMNOW LIVE - March 22-24 2019 in beautiful downtown Fort Worth. Short Lectures, interactive sessions, Q&A panels, TED (like) Talks, digital, streaming and much more. You dont want to miss this meeting! https://t.co/5TVg0Frsbf

Links:

Dr. John Cush RheumNow ( View Tweet)

The RheumNow Podcast is Up! To Needle or Not to Needle; Watch https://t.co/pjYZh5LXzi or listent to the weekly news and review https://t.co/AmXgjki2dL

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Dr. John Cush RheumNow ( View Tweet)

296 women with HTN during pregnancy (half/147 NSAID-exposed) - NSAID use was not associated with a significant change in BP (vs no NSAID) and there was no added need to start or increase BP meds in those on NSAIDS. https://t.co/csDljBJI3r

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Dr. John Cush RheumNow ( View Tweet)

AstraZeneca today announced the FDA has granted Orphan Drug Status for Fasenra (benralizumab) for Eosinophilic Granulomatosis with Polyangiitis (EGPA). Fasenra is also approved for severe, eosinophilic asthma https://t.co/4ChX8D5Evx

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Dr. John Cush RheumNow ( View Tweet)

Cohort VAMC study shows that Diabetes management (A1C, LDL, HTN) (n=368,481 patients) and outcomes were the same between physicians (n 3487), nurse practitioners (1445) and physician assistants (443). https://t.co/ToNVcPrMZN

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Dr. John Cush RheumNow ( View Tweet)

Amyotrophic lateral sclerosis, AKA Lou Gehrig’s dz (ALS), a progressive/fatal neuromuscular dz has an estimated prevalence of 5.2 per 100,000 - with a total of 16,583 cases identified. The majority of ALS patients die within 2–5 years of a diagnosis. https://t.co/Yg7aIspfnN

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Dr. John Cush RheumNow ( View Tweet)

What’s Next in Biosimilars is one of several educational videos available in the "Therapeutic Update: Biosimilars in Rheumatology" video series, sponsored by Sandoz, Inc. and now available on RheumNow. https://t.co/1vmnEJqOSi

Links:

Dr. John Cush RheumNow ( View Tweet)

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