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#ACR19 Abst#2728 Plenary: Upadacitinib RCT in AnkSpa
Improved ASAS40 at wk14 (52% v 26% PLBO, NNT~4) and SPARCC MRI Scores.
Good safety profile but too small a trial to assess properly
Overall an encouraging result, JAKi impacting yet another disease!
@RheumNow https://t.co/GtB9wHuoNp
Mike Putman EBRheum ( View Tweet)

Upadacitinib in AS
Nice to the rapid response
#ACR19 @rheumnow Abst2728 https://t.co/woAZbdb5QY
Dr Irwin Lim _connectedcare ( View Tweet)

What's your option for RA patients with MTX failure?
-Bathon: Triple therapy vs. biologic (etanercept or adalimumab)
-Bykerk: Maximize MTX to 25mg SQ
-Emery: Adalimumab is our cheapest and most effective therapy
-Mikuls: Usually TNFi, typically etanercept
#ACR19 @RheumNow
Jonathan Hausmann MD hausmannMD ( View Tweet)

Do you hold MTX in men who want to conceive? #ACR19 @RheumNow
Maeve Gamble MaeveGamble ( View Tweet)

Upadacitinib in AS
And here’s the Safety Slide
#ACR19 @rheumnow Abst2728 https://t.co/fpjhrjGp0N
Dr Irwin Lim _connectedcare ( View Tweet)

Looking forward to this PsA panel talk #ACR2019 https://t.co/pCMaqQCMsJ
Dr. John Cush RheumNow ( View Tweet)

For new diagnosis of RA: How often do you bridge with prednisone?
#ACR19 @RheumNow
Maeve Gamble MaeveGamble ( View Tweet)

Not what I was expecting:
patients reporting a diagnosis of ANCA-associated vasculitis are overwhelmingly correct, and are correct about GPA vs MPA.
If only we could say the same about lupus!
Tanaz Kermani, Jason Springer, Peter Merkel et al #ACR19 ABST2635/2641 @RheumNow https://t.co/APcqg0e5fw
David Liew drdavidliew ( View Tweet)

Quote of the day from David Borenstein at #ACR19 “Low back and neck pain are second only to the cold the most common affliction for mankind” @RheumNow https://t.co/MAX0TCXnqK
Dr. Antoni Chan synovialjoints ( View Tweet)

EAMs: I know there's published data but among Axial SpA patients you actually see, what is the most common EAM?
@rheumnow #ACR19
Dr Irwin Lim _connectedcare ( View Tweet)

A 55-year-old female found to have seropositive RA. Do you ever start a biologic first?
-Emory: we would if we could get it approved for patients predicted to have severe erosive dz
-Bathon: in women planning to become pregnant
-Mikuls: not really
@rheumnow #ACR19 https://t.co/UyeJKFTBJS
Jonathan Hausmann MD hausmannMD ( View Tweet)

What happens to PET/CT after six months of steroids in GCA? Reduction in vascular uptake, but remnant uptake didn't correlate with future clinical flares. Role of serial PET/CT in GCA yet to be determined...
@tonysammel @earlyARA #ACR19 2671 @RheumNow https://t.co/OwiqD9yMij
David Liew drdavidliew ( View Tweet)

Do you add steroids to the initial treatment of patients with RA?
-Bathon: in severe disease
-Mikuls: a conversation you should have with your patients, depending on their goals
@rheumnow #ACR19
Jonathan Hausmann MD hausmannMD ( View Tweet)

We've been asking what happens intravascularly in GCA pts on TCZ.
Five GCA pts with aortic complications on TCZ doesn't answer it, but just a reminder: TCZ is steroid-sparing, not disease-modifying. Don't take your eyes off the road!
@KantonsspitalSG #ACR19 ABST2666 @RheumNow https://t.co/G9JM4QLXSH
David Liew drdavidliew ( View Tweet)

Influenza vaccine highlights #ACR19 #whyivaccinate @RheumNow #cleclinicrheum https://t.co/NX4227Gmo9. https://t.co/iqljjr20nw
Cassandra Calabrese CCalabreseDO ( View Tweet)

Vaccination is the best mode of infection prevention. decrease frequency and severity in our patients who are at increased risk, yet vaccination rates remain so low! @LCalabreseDO @RheumNow #ACR19 #whyivaccinate
Cassandra Calabrese CCalabreseDO ( View Tweet)

Abstr#1805 per-operative csDMARD or bDMARDs not associated with 30-day post-op infection, more studies needed to determine if we truly need to hold biologics for joint replacement surgery #ACR19 @RheumNow
Cassandra Calabrese CCalabreseDO ( View Tweet)

What do you do when a patient with gout you are treating with allopurinol develops a typical allopurinol rash? #ACR19 @RheumNow
Philip Robinson philipcrobinson ( View Tweet)

RheumNow's expanded coverage of the #ACR2019 annual meeting is sponsored in part by Horizon Therapeutics. All content chosen by RheumNow and its faculty.
Dr. John Cush RheumNow ( View Tweet)

Positive conventional Ab (ANA RF CCP) don’t seem to be the special sauce linking rheum irAEs with good onc response to ICI Rx, despite prev reports linking baseline Ab to survival https://t.co/5WjeYivviG
@HSpecialSurgery prospective cohort @got_rheum #ACR19 ABST2157 @RheumNow
David Liew drdavidliew ( View Tweet)