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AS/Spondyloarthritis

MAXIMISE Trial - Secukinumab Efficacy in Psoriatic Spondylitis Patients

Feb 26, 2021

The results of the novel MAXIMISE trial have been published, demonstrating that secukinumab significantly improved axial signs and symptoms in psoriatic arthritis patients with axial manifestations with inadequate NSAID response.

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We are three weeks out from RheumNow Live. Are you planning on attending? https://t.co/vJlU0Z3Q3x

Dr. John Cush @RheumNow( View Tweet )

Feb 26, 2021

RheumNow Podcast – Sweet Lies or Hard Truths? (2.26.2021)

Feb 26, 2021

Dr. Jack Cush reviews and discusses the news and Journal reports from the past week on RheumNow.com.

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Data from Danish Medical Birth Register shows PREG women w/ spondyloarthritis have more adverse pregnancy outcomes - including preterm birth (OR 1.5), elective C-section (OR 1.44), & epidurals (OR 1.11). Not increased were preeclampsia & rate small wt. https://t.co/opYsOBAR6A

Dr. John Cush @RheumNow( View Tweet )

Feb 22, 2021
Survery of 438 RHEUMS on #AS & SpA - half use mod NY & ASAS criteria. 3/4 say Inflammatory Back Pain is axSpA specific, ~1/2 say uveitis/dactylitis are “very specific; less so heel enthesitis, peripheral arthritis. SI MRI was mor common w/ younger Rheums https://t.co/xfjvK5TO0t

Dr. John Cush @RheumNow( View Tweet )

Feb 22, 2021
RWCS Highlights - Day 2 by Dr. Rachel Tate ( @uptotate) -What’s new in Spondyloarthritis -Osteoporosis and Beyond -Immunologic basis and clinical characteristics https://t.co/q4lI2BYhfz https://t.co/Q79CHaQrHf
Dr. John Cush @RheumNow( View Tweet )
Feb 15, 2021
Upadacitinib works very well in ankylosing spondylitis. Will JAKs soon be approved in #AS @RWCSmtg @JointMD https://t.co/09KFo3mYJs
Dr. John Cush @RheumNow( View Tweet )
Feb 11, 2021
Tofacitinib shown to work very well in ankylosing spondylitis. @RWCSmtg @JointMD https://t.co/r1yIL96HyQ
Dr. John Cush @RheumNow( View Tweet )
Feb 11, 2021
But.... Etanercept was not effective in a small study of "pre-axSpA"(not having MRI SI or Elevated CRP. Low level responses in this study @RWCSmtg @JointMD https://t.co/ofIbByefMH
Dr. John Cush @RheumNow( View Tweet )
Feb 11, 2021
Eranercept works in nonrad AxSpA @RWCSmtg @JointMD https://t.co/PFTqNj6R3s
Dr. John Cush @RheumNow( View Tweet )
Feb 11, 2021
TICOSPA,. Right control in axSpA didn't work so well, even though the TV group water twice as likely to get advanced therapies @RWCSmtg @JointMD https://t.co/Jm9vHAPwCN
Dr. John Cush @RheumNow( View Tweet )
Feb 11, 2021
Dr Eric Ruderman shows x-ray progression is different/lower in non radiographic AxSpA @RWCSmtg https://t.co/tqI3xKhDuJ
Dr. John Cush @RheumNow( View Tweet )
Feb 11, 2021
Dr Eric Ruderman shows when pts are referred by MDs, vs self referred, they are more likely to have AxSpA (40 percent). Lectures from RWCS @RWCSmtg https://t.co/mRtMictVpq
Dr. John Cush @RheumNow( View Tweet )
Feb 11, 2021

ACR Promotes New COVID-19 Vaccine Clinical Guidance for Rheumatic Patients

Feb 10, 2021

The American College of Rheumatology has published a draft guidance on the use of COVID-19 vaccination in rheumatic disease and musculoskeletal disease patients, based on the efforts of the North American Task force. The document provides guidance to rheumatology providers on the use of the

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Comorbidity and Drugs Drive COVID-19 Severity and Survival in Rheumatic Disease

Feb 09, 2021

While comorbidities are associated with severe COVID-19 infection, it appears they also influence severity and survival in rheumatic disease (RMD), according to a a French cohort study,



Analysis of a French RMD cohort with SARS-CoV-2 infection analyzed the effect of inflammatory

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RheumNow Podcast – Tofacitinib Safety Concerns (2.5.2021)

Feb 05, 2021

Dr. Jack Cush reviews and discusses the news and journal reports from the past week on RheumNow.com.

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Download available--Maintaining a Healthy Immune System https://t.co/wiWzZldnik https://t.co/ZL3r3dHPC2
Dr. John Cush @RheumNow( View Tweet )
Feb 01, 2021
British registry 801 axial SpA pts; 646 did not hve fibromyalgia at baseline & 46 (7%) developed FM over time. Of 115 axSpa w/ baseline FM, 77 (2/3) recovered. FM more likely with high Dz activity ((OR 1.27) & widespread pain (OR 1.14) https://t.co/4jOdaXIJuB https://t.co/ruOYj5HmMX
Dr. John Cush @RheumNow( View Tweet )
Feb 01, 2021
Sign up for RheumNow Live, March 20 and 21st. CME credits available. https://t.co/uwxOVh142F https://t.co/GqkCLBGl62
Dr. John Cush @RheumNow( View Tweet )
Jan 31, 2021

JAK Inhibitor Misses Endpoint in Safety Study. Now What?

MedPage Today
Jan 27, 2021

Pfizer announced results Wednesday from its FDA-mandated postmarketing safety study of tofacitinib (Xeljanz), and they don't bode well for the drug and possibly others in its class.



Compared with patients taking tumor necrosis factor (TNF) inhibitors, those assigned to tofacitinib (5

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ACR Convergence 2020 Fireside Chats- top presentations in nr-axSpA, AS, axial PsA and Still’s disease. Sponsored by Novartis Medical Affairs Unable to attend the key sessions at #ACR20? Listen to the experts as they weigh in on the top abstracts. https://t.co/oGwmEXNaur https://t.co/qjwfaXXnXQ
Dr. John Cush @RheumNow( View Tweet )
Jan 27, 2021
Rheums: Got a Rheumatology question or case for RheumNow? Record it here and we'll feature it on an upcoming podcast. Tell us your name and where you practice rheumatology. https://t.co/wzNmOzH4VE https://t.co/6w8CAAUkO6
Dr. John Cush @RheumNow( View Tweet )
Jan 26, 2021
The EMA has Approved AbbVie’s Upadacitinib (Rinvoq) in the EU for the Treatment of Psoriatic Arthritis and Ankylosing Spondylitis. https://t.co/H5E8dazQx4

Dr. John Cush @RheumNow( View Tweet )

Jan 26, 2021

Low Risk of TB with Secukinumab

Jan 20, 2021

JAMA Dermatology has reported on a longitudinal cohort study of 12,319 secukinumab (SEC) treated patients (psoriasis, psoriatic arthritis, or ankylosing spondylitis); no new cases of active tuberculosis (TB) and very few cases of latent tuberculosis infection (LTBI) were found. 

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ACR Convergence 2020 Fireside Chats – Top presentations in nr-axSpA, AS, axial PsA Sponsored by Novartis Medical Affairs Unable to attend all the key sessions at #ACR20? Listen to the experts as they present their views on the top abstracts. https://t.co/r5Cf4WS63s https://t.co/zN99Jo9bO0
Dr. John Cush @RheumNow( View Tweet )
Jan 20, 2021
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