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B cell Targeted CAR-T Therapy for Autoimmune Diseases
Chimeric antigen receptor T (CAR-T) cell therapy has emerged as a transformative approach in modern medicine, demonstrating remarkable efficacy in targeting pathogenic B-cell lineages with unprecedented specificity.
Read ArticleManaging Gout in CKD Patients
A current review article addressed the management of gout patients with chronic kidney disease (CKD). This full read review addresses the epidemiology, challenges, treatment decisions and outcomes.
Read ArticlePitfalls of autoimmune serologic testing
Misuse of laboratory testing may lead to misdiagnoses and mismanagement; this is particulary prevalent when clinicians consider the use of the diagnostic use of serological autoimmune markers.
Read ArticleThe Role of Calcineurin Inhibitors in Lupus Nephritis
In the U.S, lupus nephritis affects approximately 40–50% of patients with systemic lupus erythematosus (SLE), contributing significantly to the morbidity and mortality of the affected individuals (1).
Read ArticleNEJM: Obinutuzumab in Active Systemic Lupus Erythematosus
TYK2 Inhibitor Deucravacitinib FDA Approved for Psoriatic Arthritis
Worldwide Trends in Hyperuricemia
Long-Term Hydroxychloroquine Retinopathy Risk
Key Takeaways
- Hydroxychloroquine (HCQ) is used to treat many rheumatologic conditions, but retinopathy and vision loss can occur with long-term dosing.
- For HCQ-related retinopathy, solid estimates of prevalence, incidence over time,
Progress in GCA and Takayasu's Arteritis
I recently attended a fascinating lecture by Dr. Anisha Dua on progress in the diagnosis and treatment of large-vessel vasculitis, with a focus on giant cell arteritis (GCA) and Takayasu's arteritis.
Read ArticleOsteoporosis: Thinking outside the box
I recently attended a talk at RWCS by Dr. Gina Woods from UC San Diego on osteoporosis. As rheumatologists, most of us manage osteoporosis in some form every single day. If there is one constant in this space, it’s that osteoporosis care keeps evolving.
Read ArticleOpen-access Arthralgia Clinics
Long-Term Bimekizumab Safety Data
Key Takeaways
- Bimekizumab is approved for psoriasis, spondyloarthritis (SpA), psoriatic arthritis (PsA), and hidradenitis suppurativa, but has not been on the U.S.
Early vs Delayed Belimumab in Lupus
An economic evaluation of early vs delayed use of the Blys inhibitor, belimumab (BEL), in systemic lupus erythematosus (SLE) has shown both cost effectiveness and clinical utility of early BEL initiation in active lupus patients.
Read ArticleSupportive vs Flexible Footwear in Hip Osteoarthritis
FDA Approves Icotrokinra for Plaque Psoriasis
Today the FDA approved an oral IL-23 inhibitor, icotrokinra (Icotyde), for use in moderate-to-severe plaque psoriasis in adults and children 12 years of age and older (who weigh at least 40 kg) who are candidates for systemic therapy or phototherapy, according to a
Read ArticleEquivalent Healthcare Outcomes by Nurses and Physicians
With increasing demand for health services in an aging population, serving complex patients with comorbidities, and increasing healthcare costs, the question of whether nurses can substitute for physicians was addressed by a recent Cochrane review.
b/ts-DMARDs Do Not Arrest Bone Loss in RA
In rheumatoid arthritis (RA), the goal is to control or arrest inflammation such that articular and bony damage is halted.


