RheumNow Podcast – Mistakes with Steroids
Apr 08, 2021
Dr Jack Cush gives his spin on this week's RheumNews and Rheum Research from RheumNow.com.
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Rheumatology Care Derailed by COVID-19
Apr 06, 2021
A survey study from the ArthritisPower PPRN or CreakyJoints database shows that during the COVID-19 pandemic patient care was substantially affected in unforeseen ways.
Data from the ArthritisPower Patient-Powered Research Network and CreakyJoints patient community were gathered by
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RheumNow Podcast – Upadacitinib Wins in PsA (4.2.2021)
Apr 02, 2021
Dr Jack Cush reviews the news and Journal reports and takes "Back Talk" questions from viewers.
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Upadacitinib Clinical Efficacy in Psoriatic Arthritis
Apr 01, 2021
McInnes and colleagues have published the results of the SELECT - PsA trial in NEJM showing updacitinib (UPA) to be superior to placebo in active psoriatic arthritis (PsA) patients, with 15 mg UPA equal to adalimumab (ADA) and 30 mg UPA qd being superior to ADA.
Janus kinase
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Inflammatory Conditions Up the Risk of Premature Myocardial Infarction
Mar 31, 2021
The European Journal of Preventive Cardiology reports that younger patients with their first myocardial infarction before age 50 yrs have a higher risk of having a systemic inflammatory disease (SIDs) and higher rates all-cause mortality.
Data derived from the retrospective
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Metanalysis of 32 studies shows most forms of arthritis assoc w/ incr risk of CVA (ischemic stroke: RR=1.53 or hemorrhagic stroke: RR=1.45), esp for RA (RR=1.38), AS (RR=1.49), PsA (RR=1.33), gout (RR=1.4) --risk higher with age <45 years (RR=1.46) https://t.co/YDiebrqtbi
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Dr. John Cush @RheumNow( View Tweet )
Mar 31, 2021
Psoriatic Disease Management - RNL 2021 Highlights
Mar 29, 2021
This year’s coverage of psoriatic arthritis was once again, both exciting and informative. Topics included an overview of the latest therapeutic options, an excellent discussion on psoriasis specifically, and the epidemiology of psoriatic arthritis.
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Takeaways from #RNL2021 from Dr. Rachel Tate ( @uptoTate )
"Severe flares in PsO pts previously well controlled: look for infection (HIV or other) and/or underlying malignancy. Melodie Young, NP #RNL2021"
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Dr. John Cush @RheumNow( View Tweet )
Mar 29, 2021
Our in-person participants engaging with the psoriatic panel #RNL2021 https://t.co/N0Cdos3Rhb
Dr. John Cush @RheumNow( View Tweet )
Mar 20, 2021
Top 4 arthritis types that significantly increase the risk of CVA: 1) RA (RR=1.38), 2) ankylosing spondylitis (RR=1.49), 3) psoriatic arthritis (RR=1.33) & gout (RR=1.4). With these, the risk was higher in younger (<45 yrs) (RR = 1.46), not older (>65) https://t.co/Snb6OrtZJH
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Dr. John Cush @RheumNow( View Tweet )
Mar 19, 2021
SPIRIT‐P3 RCT treated biologic‐naive PsA with ixekizumab x36 wks; those w/ MDA x 3 mos were randomized to continue or withdraw IXE (blinded). There were significantly more relapses when IXE was stopped; most regained control when started https://t.co/lhQ8X1Ef48
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Dr. John Cush @RheumNow( View Tweet )
Mar 19, 2021
RheumNow Podcast – Great Associations (3.19.2021)
Mar 18, 2021
Dr. Jack Cush rants on the journal reports, news and FDA actions featured this past week on RheumNow.com.
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Are You a Super Rheum?
Mar 18, 2021
Several weeks ago, at the Rheumatology Winter Clinical Symposia, an interesting debate between Drs. Orrin Troum and Marty Bergman hashed over the concept of whether rheumatologists should sub-specialize with a practice, research or career devoted to one disease ("Super Rheum"), or be "selective
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Apremilast Equals MTX in Palmoplantar Psoriasis
Mar 18, 2021
Palmoplantar psoriasis (PPP) is a therapeutically challenging variant of psoriasis; nonetheless, a prospective, randomized, active-controlled trial from India suggests that apremilast is effective and safe in patients with PPP.
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Rinvoq (upadacitinib) was slated for a psoriatic arthritis indication this month, but now that has been pushed back ~90days, pending further FDA review of the benefit-risk profile for upadacitinib in psoriatic arthritis https://t.co/FeBOrNIbTo
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Dr. John Cush @RheumNow( View Tweet )
Mar 17, 2021
Enthesitis Responses to Secukinumab in Spondylitis Patients
Mar 16, 2021
Schett and colleagues studies the secukinumab (an IL-17 inhibitor) response in patients from 3 clinical trials with enthesitis and ankylosing spondylitis (AS) and demonstrated consistent efficacy with improved enthesitis scores at both peripheral and axial sites.
Pooled data from the
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Rheumatic Patients Are at Risk for COVID Death
MedPage Today
Mar 16, 2021
Patients with rheumatic diseases who developed COVID-19 were at increased likelihood of death, with risk factors similar to those seen in the general population but also because of factors specific to their underlying disease and its treatment, analysis of data from an international registry
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RheumNow Live starts one week from today!
The 2021 RheumNow Live current speaker list includes:
Roy Fleischmann, Clay Cockerell, Eric Ruderman, Alexis Ogdie, Philip Robinson, Jeff Sparks, Nigel Haroon, Artie Kavanaugh, and Jack Cush.
Register today.
https://t.co/Woxi4Ri0O5 https://t.co/nbm4AFXmlv
Links:
Dr. John Cush @RheumNow( View Tweet )
Mar 13, 2021
Low IBD Risk with IL-17 Inhibition
Mar 08, 2021
Incident or worsening colitis is a rare complication of IL-17 inhibitor therapy; a real world study confirms very low rates of new IBD in patients starting secukinumab.
A real-world study of the secukinumab (SEC; an IL-17 inhibitor) and gastrointestinal related adverse events (GIRAE)
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RheumNow Podcast – Pounds of Prevention (3.5.2021)
Mar 04, 2021
Dr. Jack Cush reviews and discusses nearly a dozen news reports and journal articles from the past week on RheumNow.com.
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Report from DANBIO Danish register looked at chronic pain in a matched cohort study of Psoriasis. Chronic pain was not associated with excess mortality (hence not PsA) (OR 0.99,0.95-1.03). Mortality was increased with steriods, COPD, DM, CA, CV disease. https://t.co/91JW3BOPtw
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Dr. John Cush @RheumNow( View Tweet )
Mar 02, 2021
News Feature: MAXIMISE Trial - Secukinumab Efficacy in Psoriatic Spondylitis Patients
https://t.co/34RU4OSaRi
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Dr. John Cush @RheumNow( View Tweet )
Feb 28, 2021
MAXIMISE Trial - Secukinumab Efficacy in Psoriatic Spondylitis Patients
Feb 26, 2021
The results of the novel MAXIMISE trial have been published, demonstrating that secukinumab significantly improved axial signs and symptoms in psoriatic arthritis patients with axial manifestations with inadequate NSAID response.
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We are three weeks out from RheumNow Live. Are you planning on attending?
https://t.co/vJlU0Z3Q3x
Links:
Dr. John Cush @RheumNow( View Tweet )
Feb 26, 2021
RheumNow Podcast – Sweet Lies or Hard Truths? (2.26.2021)
Feb 26, 2021
Dr. Jack Cush reviews and discusses the news and Journal reports from the past week on RheumNow.com.
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Staying Abreast of COVID-19
Mar 24, 2020
