Skip to main content

Psoriatic Arthritis (PsA)

RheumNow Podcast – Good Time Charlie…. (10.16.20)

Oct 15, 2020

Dr. Jack Cush sings the news and journal reports from the past week on RheumNow.com.

Read Article

Tofacitinib and Thromboembolic Risk

Oct 13, 2020

Mease and colleagues have reviewed the tofacitinib drug development and clinical trial data, finding the risk of venous (VTE) and arterial thromboembolism (ATE) to be low and augmented in patients with baseline cardiovascular abd VTE risk factors and those taking higher doses of tofacitinib (

Read Article

RheumNow Podcast – Bad Disease & Bad Outcomes (10.9.20)

Oct 08, 2020

Dr. Jack Cush Reviews the news and journal articles from the past week on RheumNow.com.

Read Article

RheumNow Podcast – Function Follows Form (10.2.20)

Oct 01, 2020

Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com. Regulatory approvals, update on global rheumatology alliance, smoking and psoriasis, gabapentin let down and defining difficult RA.

Read Article
Swiss cohort of 666 axSpA, RA & PsA pts seen before, during & after COVID; consults dropped 52%, remote visits increased 129%, & non-compliance slightly increased during COVID (axSpA 20% vs 13% before, p=0.003); but no incr in flares(<15%) or Dz activity

Dr. John Cush RheumNow ( View Tweet)

Oct 01, 2020

Low Risk of Latent TB with Secukinumab

Oct 01, 2020

TB reactivation and latent tuberculosis infection (LTBI) are warned against with biologic agents, especially TNF inhibitors; yet clinical trial data now shows that the risk of LTBI with IL-17 inhibition via secukinumab is uncommon.

Read Article
Meta-analysis shows smoking increases the risk of psoriasis (OR: 1.84) in the general population, but smoking the risk of PsA among psoriasis patients (OR: 0.70) but was equal to the general populatoin. https://t.co/4MkpkFQlqr

Dr. John Cush RheumNow ( View Tweet)

Oct 01, 2020
Today Janssen announced the FDA has approved golimumab (Simponi Aria) for use in children (> 2yrs) with active Polyarticular Juvenile Idiopathic Arthritis and for pediatric Psoriatic Arthritis https://t.co/ntWJXjEJvc

Dr. John Cush RheumNow ( View Tweet)

Sep 30, 2020

RheumNow Podcast – Cardiovascular Risk in Psoriatic Disease (9.25.20)

Sep 24, 2020

Dr. Jack Cush reviews the news and Journal articles from the past week on RheumNow.com.

Read Article

EULAR Updated 2019 Recommendations for Psoriatic Arthritis Management

Sep 24, 2020

In June 2020, we failed to report on the ARD publication updating the 2019 update the European League Against Rheumatism (EULAR) recommendations for the pharmacological treatment of psoriatic arthritis (PsA) - these are presented below.



This guideline committee included 28

Read Article

Ustekinumab Early Risk for Cardiovascular Events

Sep 23, 2020

JAMA Dermatology reports a claims-based, case-time-controlled French study of 9290 psoriasis patients suggesting that ustekinumab initiation may be associated with an increased risk of acute coronary syndrome or stroke in high risk cardiovascular patients.

Read Article

CXCR3 and Restricted T Cells in Psoriatic Arthritis Inflammation

Sep 21, 2020

Research from Oxford University suggests a potential pathogenic role for the chemokine CXCR3 and clonally restricted CD8+ T cells in the pathogenesis of psoriatic arthritis (PsA) based studies of PsA synovial fluid samples obtained by arthrocentesis from 11 patients with large-joint oligo PsA

Read Article

RheumNow Podcast – Lupus Delights (9.18.20)

Sep 18, 2020

Dr Jack Cush reviews the news and journal reports from the past week on RheumNow.com:

Read Article
Systematic literature review of the incidence of SpA subtypes: psoriatic arthritis overall IR of 9.7 per 100.000 PYs; AS overall IR of 4.8/100kPY, and reactive arthritis overall IR estimate of 3.4/100KPY.

Dr. John Cush RheumNow ( View Tweet)

Sep 15, 2020

Comorbidities Impact Disease Activity in Spondyloarthritis

Sep 13, 2020

An analysis of a large population-based cohort of axial spondyloarthritis (axSpA) patients shows that comorbidities are common and are associated with higher disease activity and higher levels of functional impairment.

Read Article
Swedish registry comparison of 541 PsA 40944 non-PsA pregnancies between 1997-2014, shows PsA pregnancies had increased risks for preterm birth (adj OR 1.63) and caesarean deliveries (OR 1.47), but no increased risks for pre-eclampsia, stillbirth https://t.co/3Udpjh

Dr. John Cush RheumNow ( View Tweet)

Sep 13, 2020

ACR 2020 Reproductive Guidelines - Lactation Guidance

Sep 10, 2020

In this third excerpt from the ACR guidelines on managing reproductive health issues in rheumatic disease patients, we present recommendations regarding the use of glucocorticoids and guidance on lactation and medication use post-partum.

Read Article

ACR 2020 Reproductive Guidelines - Medication Use with Pregnancy

Sep 09, 2020

The American College of Rheumatology (ACR) has published guidelines to manage reproductive health issues in rheumatic disease (RMD) patients before, during and after pregnancy. In this second exerpt from their guidelines articles we present recommendations (and good clinical practice

Read Article

ICYMI - 11 Pearls for Pregnancy Management in Rheumatoid Arthritis

Sep 09, 2020

Rheumatoid arthritis affects women in their child-bearing years and many will face the issue of pregnancy and RA management at some point. Here are11 considerations for those managing RA patients who wish to become pregnant.



Read Article

ACR 2020 Reproductive Guidelines - Contraception & Counseling

Sep 08, 2020

The American College of Rheumatology established a guidelines committee that consisted of both patients, rheumatologists and maternal-fetal health experts. After a a systematic review of the medical literature regarding contraception, assisted reproductive technology, fertility preservation,

Read Article

Treatment Options for Extraintestinal IBD

Sep 03, 2020

Extraintestinal manifestations (EIMs) frequently accompany inflammatory bowel disease, often augmenting morbidity and mortality are associated with disease activity and may increase the need for surgery or treatment escalation.  A recent review in GUT details the treatment options for patients

Read Article
Non-Radiographic Axial Spondyloarthritis has Its Own Diagnostic Code; As of October 2020, nr-axSpA will be officially included in the 10th version of the International Classification of Diseases (ICD-10) coding manual as M46.8 https://t.co/AftIecd2z3
Dr. John Cush RheumNow ( View Tweet)
Aug 30, 2020

Sleep, Fatigue and Depression in Psoriatic Arthritis

Aug 28, 2020

Comorbidities are highly prevalent in psoriatic disease. A recent study in Arthritis Research & Therapy suggests a high prevalence of sleep disturbances, fatigue, and anxiety/depression in psoriatic arthritis (PsA) that is unrelated to skin disease musculoskeletal (MSK)

Read Article

RheumNow Podcast – Rheum Lives Matter (8.28.20)

Aug 28, 2020

Dr. Jack Cush reviews the news and journal articles from the past week. Of mice and men in cartilage, the efficacy of JAK inhibitors in patients who are having skin problems, nrAxSpa has its own diagnostic code, metformin, talking about Back Talk, plus so much more.

Read Article

Durability of Total Shoulder Arthoplasty

Aug 27, 2020

A systematic review of the outcomes of total shoulder replacements (TSR), humeral hemiarthroplasties, and reverse total shoulder replacements finds that approximately 90% of shoulder replacements last for longer than 10 years with good patient-reported outcomes.



This metanalysis

Read Article
×