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Psoriatic arthritis

Lancet forecasts that in Australia 5.4 million will have arthritis 2040, a 31% increase 4.1 mill in 2025. Included 3.2 w/ OA, ~750K w/ RA, & 8500 w/ JIA. OA incr in males from 6.3% to 7% (2040). & 10.8 to 12.2% in F. RA will grow from 1.56 to 1.75% in males and 2.6 to 2.9% in… https://t.co/6DM0ZLlZ05 https://t.co/djPP1cUDOI
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BMJ has published an extensive, full read review of the Advances in the management of psoriatic arthritis in adults - by Drs. Gladman and Kharouf, (great read and reference!) https://t.co/4Bz3Vq93jH https://t.co/ZhwKZ4XmNy
Dr. John Cush @RheumNow( View Tweet )
Another Stelara (Ustekinumab) biosimilar was FDA approved on 12/1 -- called Yesintek for the treatment of Crohn’s, Ulcerative Colitis, Psoriasis & PsA. This makes 6 FDA approved biosimilars for ustekinumab.https://t.co/SMKx1LnBB1 https://t.co/96u5YuvyIf
Dr. John Cush @RheumNow( View Tweet )
ICYMI: Improving the Value of Musculoskeletal Ultrasound in Rheumatology Care MSUS has emerged as a powerful asset in rheumatology, providing a real-time, non-invasive, and cost-effective solution for diagnosing and managing inflammatory arthritis conditions such as RA and PsA.… https://t.co/94i7NZGSJH https://t.co/XiSLNaLuf9
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ICYMI: Evaluation of Bimekizumab in PsA

Bimekizumab (BKZ) is a monoclonal IgG1 antibody that selectively inhibits interleukin (IL)‑17A and F. There have been more updates on the 2 year data on BKZ at #ACR24, and this is a summary of four studies being presented this year at ACR24.

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Don’t Buy Guitars (12.6.2024)

This year at ACR24, the RheumNow faculty and reporters were prolific, generating >800 Tweets, 56 written articles, 117 Videos and 28 podcasts – all in 4 days! You can best review and learn ACR24 by A) Rheumatology Roundup; b) Topic Panel videos; and c) Topic podcasts.

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Will the Robots Save Ultrasound? Ultrasound has a lot going for it in rheumatoid arthritis and psoriatic arthritis. It is free of ionizing radiation, yet can deliver helpful insights to the bedside, educating our patients along the way. As we seek to prognosticate more and… https://t.co/2JL2be3RMj https://t.co/4oQy6gcQVS
Dr. John Cush @RheumNow( View Tweet )

Infertility linked to post-childbrith onset of systemic autoimmune disease

EurekAlert!

Women who experience infertility but do not use fertility treatments have a higher risk of developing a group of conditions called systemic autoimmune rheumatic diseases (SARD) in the nine years after a naturally conceived birth compared to women without fertility problems.

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BMJ has published an extensive, full read review of the Advances in the management of psoriatic arthritis in adults - by Drs. Gladman and Kharouf, (great read and reference!) https://t.co/21SHvGyUZH https://t.co/grDr5mfAzn
Dr. John Cush @RheumNow( View Tweet )
ACR24 IL-17 Topic Panel: Advancing Care with IL-17 Pathway Insights https://t.co/t9QQDYIrda

Dr. John Cush @RheumNow( View Tweet )

Diagnostic Delays in PsA Despite the remarkable expansion of the therapeutic armamentarium for psoriatic arthritis (PsA), the MONITOR-PsA study (abstract 1456) highlights a persistent and critical issue: delays in diagnosis. https://t.co/83TeIpfutP https://t.co/85qo7F9IPa
Dr. John Cush @RheumNow( View Tweet )

ICYMI: Improving the Value of Musculoskeletal Ultrasound in Rheumatology Care

Unlike traditional imaging techniques, MSUS can be easily used at the point-of-care and offers high-resolution images of joints, tendons, and soft tissues, facilitating the early detection of inflammation and structural damage. On Saturday, November 16th at the ACR Convergence 2024, Dr. Veena

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ACR24 JAK/TYK Topic Panel https://t.co/xTDnwjEXE6

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J&J has submitted 2 supplemental BLAs applying for FDA approval of guselkumab( Tremfya) for use in juvenile plaque psoriasis & juvenile (>5-6 yrs age) psoriatic arthritis based on several phase 3 RCTs. https://t.co/dAkH219pzN https://t.co/R9yJCSOVJa
Dr. John Cush @RheumNow( View Tweet )
Another Stelara (Ustekinumab) biosimilar was FDA approved on 12/1 -- called Yesintek for the treatment of Crohn’s, Ulcerative Colitis, Psoriasis & PsA. This makes 6 FDA approved biosimilars for ustekinumab.https://t.co/ASErsKTNQ6 https://t.co/d1BRW92vju
Dr. John Cush @RheumNow( View Tweet )
ACR24 PsA Topic Panel Advancing Care for Psoriatic Arthritis Tune in for an engaging discussion at the ACR Annual Meeting! This expert panel will explore the latest breakthroughs and trends in Psoriatic Arthritis(PsA) research and management, providing actionable insights for… https://t.co/j0063RpVCi https://t.co/LCINZvUR5s
Dr. John Cush @RheumNow( View Tweet )
The Psoriatic March: PsA before PsO https://t.co/lRCrzdKX7Z https://t.co/eabYe3GXrM
Dr. John Cush @RheumNow( View Tweet )

Novel TYK2 inhibitor Zasocitinib

Similar to JAKs, TYK2 is an important mediator of innate and adaptive immune activation. Unlike JAKs, however, TYK2 is thought to play a minimal role in other pathways, such as metabolic and hematopoietic axes. Therefore, it is hypothesized that TYK2-targeted agents could be effective in

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Diagnostic Delays in PsA

Despite the remarkable expansion of the therapeutic armamentarium for psoriatic arthritis (PsA), the MONITOR-PsA study highlights a persistent and critical issue: delays in diagnosis. The study findings are stark, with about 25% of patients having erosions at diagnosis.

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Anti IL-17 on Entheseal Biopsy in PsA Dr. Eric Dein reports on abstract 2586, presented at #ACR24 https://t.co/2JCFnB8HNq https://t.co/2MFCiNnvj2
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Best Things I Saw Today in PsA Dr. Catherine Bakewell reviews several studies presented at #ACR24. https://t.co/eIMdoSvkFh https://t.co/aSBEgFegNr
Dr. John Cush @RheumNow( View Tweet )
Novel and Emerging Therapies in Psoriatic Arthritis Recent advancements in targeted therapies, including selective inhibitors of key inflammatory pathways, offer promising outcomes for patients with active psoriatic arthritis (PsA). At ACR 2024, there have been further… https://t.co/vBexcBrTQ6 https://t.co/gWpIYKMPnx
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PsA Ultrasound Updates Dr. Catherine Bakewell and Dr. Lihi Eder discuss updates on ultrasound in psoriatic arthritis at #ACR24. https://t.co/DZBe8uNpJS https://t.co/wIS1hUZnAS
Dr. John Cush @RheumNow( View Tweet )
PsA Ultrasound Updates Dr. Catherine Bakewell and Dr. Lihi Eder discuss updates on ultrasound in psoriatic arthritis at #ACR2024 https://t.co/XJOuKl8lCF https://t.co/XPMlf3sOnU
Dr. John Cush @RheumNow( View Tweet )
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