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The Benefits of a Lupus Clinic

d Jack Cush, MD

A comparative cohort study assessing the quality of care in patients with systemic lupus erythematosus (SLE) suggests that a dedicated lupus clinic has better quality measure performance compared to lupus management in a general rheumatology clinic.

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PRAIRI Study - Can RA Be Prevented?

d RheumNow

B-cell depletion may offer a means of delaying the onset of clinical arthritis in adults at high risk, according to the PRAIRI study - a proof-of-mechanism study in pre-clinical RA patients. 

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New ACR/NPF Guidelines for Management of Psoriatic Arthritis

d Jack Cush, MD

The American College of Rheumatology (ACR) and National Psoriasis Foundation (NPF) have released a joint treatment guideline for psoriatic arthritis (PsA) that provides evidence-based pharmacologic and non-pharmacologic recommendations and includes recommendations on other management issues inclu

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Dendrimer Nanocarrier Delivers IGF-1 to Degenerative Cartilage

d Jack Cush, MD

Researchers from MIT have developed a novel treatment for osteoarthritis (OA) by using dendrimer-based nanocarriers to deliver insulin-like growth factor 1 (IGF-1) to chondrocytes within joint cartilage and in animal models have shown when these nanocarriers injected into rat knees in models of O

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Limited Impact of Vitamin D Supplementation

d Jack Cush, MD

A systematic review of 81 studies on vitamin D concludes that vitamin D supplementation does not prevent fractures or falls, or have clinically meaningful effects on bone mineral density.

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Direct Antiglobulin Test (DAT) or Coombs test reviewed in JAMA - hemolysis can be suggested by low haptoglobin, high LDH &reticulocytosis- a positive IgG DAT indicates warm AIHA. An IgM & anti-C3d activity --> cold agglutinin Dz https://t.co/XLZHtISTjn

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An interesting read in JAMA - how a patient developed his own "tool kit" to manage fibromyalgia - cannibis, exercise, diet, massage, PT, CBT. A story of serendipity, inadequate insurance coverage & woefulness of current pain management https://t.co/DIiuqSbkJ8

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CARRA reports it has completed enrollment of 403 newly diagnosed polyarticular JIA patients in STOP-JIA (Start Time Optimization of Biologic Therapy in Polyarticular JIA). Results anticipated in late 2019. https://t.co/V2qvZCRXvs

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Retrospective study of 65 093 obese adults w/ bariatric surgery shows that, although Rouxen-Y gastric bypass had more wt. loss than gastric sleeve > gastric banding; RYGB had more 30-day major adverse events - Gastric Sleeve wins? https://t.co/R0Fday00Bh

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Interdisciplinary guidelines for treating Uveitis in JIA - 1) Topical steroids; 2) if not improved, MTX; 3) Then TNF inhibitor; 4) systemic steroids; or 5) other biologics (TCZ, ABA, RTX). https://t.co/6D1aq3xQqA

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Dr. John Cush RheumNow ( View Tweet)

Cohort study 56866 RA/PsA/AS patients compared 287 w/ multiple myeloma & 2760 matched controls - no difference in MM risk related to biologic, DMARD or NSAIDs. But compared to DMARD only pts, Biologic + DMARD users had a 48% lower risk of MM (OR 0.52) https://t.co/DsmvNXC9c9

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Open source review Assessing Disease Activity in Psoriatic Arthritis: A Literature Review by Drs Tucker, Coates, Helliwell. How to assess arthritis, dactylitis, enthesitis, axial disease, skin & patient measures (PROMs). https://t.co/5SLwpeGbkn

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Depression worsens back pain; increases healthcare costs. Medicare claims study 73,000 found 6,739 with back pain & 20% of these (1310) had depression. Annual healthcare costs substantially higher in LBP pts w/ depression ($13,153 vs $7,477, P < 0.001). https://t.co/rHqfWPTV7r

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CDC reports that 40-47% of adults have had a flu vaccination in the past 12 months (higher in elderly (67%). https://t.co/RPmkTECeF7

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Bisphosphonate safety review — risk of Atypical Femoral Fracture is 1/1000 and risk of osteonecrosis of the jaw is 1/10,000. One-third of IV zolendronic acid pts will have arthralgia/myalgias or flu like sxs. https://t.co/80xBkZlKgn

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FDA has approved Genentechs ACTpen - a tocilizumab autoinjector 162 mg sc for use in RA, GCA, poly and systemic JIA - should be available in January 2019. https://t.co/YzFHyYxQlS

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Study of 2053 RA patients from VA medical centers found 27% with chronic lung disease that confered a 51% increased mortality risk; sadly this was not altered by MTX or biologic therapy. https://t.co/nYFnScSXQ4

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Dr. John Cush RheumNow ( View Tweet)

I prefer more slides with less data per slide rather than fewer slides jam packed with multiple miniscule figures #ASH18

John P. Leonard, MD JohnPLeonardMD ( View Tweet)

We are not only doctors for the elderly. Many of our patients are young or even children. Sometimes we treat banal conditions but also we manage severe & autoimmune disorders with systemic involvement. We use innovative therapies. Didn't you know us? We are the Rheumatologists

Emilio Martin Mola emartinmola ( View Tweet)

This is a great conference! https://t.co/GEDlj44jLE

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