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RheumNow Podcast – Better Ways to Treat Gout (11.8.19)
Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com.
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T2T Lowers Mortality in Gout
A Spanish prospective cohort of active, uncontrolled gout patients were followed and showed that failure to reach a target serum uric acid (sUA) level of 6 mg/dl (0.36 mmol/L) or less was associated with a 2-3 fold increase in mortality.
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RITAZAREM Trial
Fixed interval 4 monthly repeat dose Rituximab vs Aza for maintenance
Pop: AAV at relapse, given 375mg/m2
Rituximab seemed superior
#ACR19 @rheumnow
More details Abst0806
Dr Irwin Lim _connectedcare ( View Tweet)
EMA has approved the subcutaneous version of CT-P13 an infliximab biosimilar based on this trial by Rene Westhovens. Equal efficacy of IV and SC CT-P13 with great maintenance on SC form. Interestingly high trough levels with SC CT-P13. #ACR19 @RheumNow Abst 807 https://t.co/hfrtJRMPdt
Dr. John Cush RheumNow ( View Tweet)
In you #SLE pts how do you routinely assess CV risk
Dr. John Cush RheumNow ( View Tweet)
Great data on reducing low benefit care in rheum pathology ordering. Reducing dsDNA requests in patients with a negative ANA #ACR19 @RheumNow Abstract 0265 https://t.co/b5gWwPi487
Philip Robinson philipcrobinson ( View Tweet)
RheumNow’s expanded coverage of the #ACR2019 annual meeting is sponsored in part by Sanofi Genzyme and Regeneron. All content chosen by RheumNow and its faculty.
Dr. John Cush RheumNow ( View Tweet)
Abstract 0348 #gout Details of the changes over time in gout medications in US RISE database.
Allopurinol and pegloticase slowly grinding higher… Lesinurad increased significantly in comparison
@RheumNow #ACR19 https://t.co/VcqNtB2eXN
Philip Robinson philipcrobinson ( View Tweet)
CVS risk in black patients with SLE (retro cohort)
18x higher in early SLE & over long-term, 6x
Highest risk at 1 and 10yrs after SLE diagnosis
Discoid rash 3x assoc with CVD
#ACR19 @rheumnow Abst0805
Dr Irwin Lim _connectedcare ( View Tweet)
Holy smokes! 18x higher risk of cardiovascular disease in Black SLE patients, highest at 1 and 10 years after diagnosis - Dr Shivani Garg #ACR19 @rheumnow #Abstr #ACRBest https://t.co/kXoMNu4QKb
Jonathan Hausmann MD hausmannMD ( View Tweet)
Pneumococcal vaccine recommendations for pts with AID are confusing and data is C level - but we still recommend prime/boost administration of PCV13 followed by PPSV23 @RheumNow @LCalabreseDO @BetsyKirch #ACR19 #cleclinicrheum https://t.co/WFBjQRRgmb
Cassandra Calabrese CCalabreseDO ( View Tweet)
Plenary session shows AA/blacks at higher risk for #SLE & that blacks have 16 fold increased risk for IHD, CVD. CV risk accelerated at yrs 1 & 10. Copy & paste. #ACR19 @RheumNow Abst 805 #ACRBest https://t.co/kgfwjd1XOc
Dr. John Cush RheumNow ( View Tweet)
RheumNow’s expanded coverage of the #ACR2019 annual meeting is sponsored in part by Horizon Therapeutics. All content chosen by RheumNow and its faculty.
Dr. John Cush RheumNow ( View Tweet)
What percentage of your SLE and RA patients receive HCQ above the 5mg/kg recommended by AAO? #ACR19 @rheumnow #Abstr #ACRBest
Jonathan Hausmann MD hausmannMD ( View Tweet)
How do you taper steroids in RA?
I take a personalised approach i.e. I guess based on experience of similar pt situations & what I think the pt will tolerate.
Is it evidence-based? Not really.
Is there any evidence to guide it? Well...😐
@umichmedicine #ACR19 ABST0554 @RheumNow https://t.co/YFlvyYuBee
David Liew drdavidliew ( View Tweet)
MTX and RTX significantly reduce immunogenicity it flu and pneumonia vaccines. When possible, time appropriately! @RheumNow @LCalabreseDO #ACR19 https://t.co/udmqkbLG64
Cassandra Calabrese CCalabreseDO ( View Tweet)
@RheumNow #ACR19 https://t.co/fmLAr2X4y5
Olga Petryna DrPetryna ( View Tweet)
Black vs White US data
2-3x incidence in black patients
Deaths 13yrs sooner with 2-3x higher mortality
#ACR19 @rheumnow Abst0805
Dr Irwin Lim _connectedcare ( View Tweet)
By the way, how many of you use low dose aspirin routinely in SLE pregnancies?
#ACR19 @rheumnow
Dr Irwin Lim _connectedcare ( View Tweet)
What imaging do you use in gout? Check out the updated PANLAR recommendations abst#301 @RheumNow #ACR19
Dr. Rachel Tate uptoTate ( View Tweet)
