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Can the Focus Score predict Lymphoma in Sjogren’s syndrome?
Patients with Sjogren’s syndrome are nearly 19 times more likely to develop lymphoma, so identifying factors that impact this risk development is a major goal in caring for this disorder.
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Sinusitis Activity Linked to Brain Dysfunction
Have you wondered why fibromyalgia, fatigue or cognitive dysfunction often co-associate with chronic sinusitis?
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Answering questions on how COVID-19 affects rheumatic patients
As we inch closer to a possible vaccine for COVID-19, we are finally filling in the details on how the pandemic is affecting every aspect of our patient’s lives.
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Can the Focus Score predict Lymphoma in Sjogren’s syndrome? by Dr. Eric Dein ( @ejdein1 )
https://t.co/B5HN6ju3ru https://t.co/3MuXH66YqJ
Links:
Dr. John Cush RheumNow ( View Tweet)
Do B-cell targeted therapies still have a place for the treatment of Sjogren’s? #EULAR2021
https://t.co/96sv3beMvG https://t.co/EWKCA1KGsC
Links:
Dr. John Cush RheumNow ( View Tweet)
#EULAR2021 POS0230: TNFi changes intestinal microbiota in IBD-SpA
⬇️ Proteobacteria
⬆️Lachnospiraceae, Coprococcus
Does inflammatory changes by TNFi restore intestinal eubiosis and does this affect SpA outcomes?
@Rheumnow
Eric Dein ejdein1 ( View Tweet)
Talk about unmet need. We must get better Rx for #Sogren’s Syndrome! Large survey show quality of life v poor in SS & correlates with degree of dryness in lacrimal & salivary glands POS0102 #EULAR2021 @eular_org @RheumNow
Janet Pope Janetbirdope ( View Tweet)
If we want drugs to be effective in #Sjogren’s Syndrome we need to see activity. The #Eular SS disease activity index ~ESSDAI in 511 SS pts found >50% w moderate to severe values BUT how much is Reversible ie fibro, fatigue, scarred glands? POS0105 @RheumNow @eular_org #EULAR2021
Janet Pope Janetbirdope ( View Tweet)
Does anti-CD20 mAb still have a place in #Sjogren? Dr Pontarini analysed salivary gland biopsy from TRACTISS and reported beneficial effects of RTX in⬇️regulating genes involved in immune cell recruitment, activation and organisation in ectopic GC #EULAR2021 #OP0136 @RheumNow https://t.co/FRUvo4JxTx
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
Sjogren’s QoL reported dryness correlates with objective salivary flow
⭐️lower perceived dryness associated with higher immunologic activity
Abs#POS0102
#EULAR2021 @RheumNow
Robert B Chao, MD doctorRBC ( View Tweet)
Don’t forget to check the eyes. Dr Kolfenbach. Top secret and Pearls #ACR20 @RheumNow It’s also useful for dx #sjogren #sarcoidodis #Ig G4 https://t.co/dxmwuwrPqz
Sole RetamozoSole ( View Tweet)
Myths surrounding #sjogren. Complications of severe dry eye. Dr Akpek #ACR20 @RheumNow https://t.co/gnZJfcpsGn
Sole RetamozoSole ( View Tweet)
Living with #Sjogren #syndrome. Tips for dry mouth management. Dr Papas #ACR20 @RheumNow @ramos_casals https://t.co/uw4NH3yhpn
Sole RetamozoSole ( View Tweet)
#sjogren #syndrome poster session #ACR20 @RheumNow Clinical characteristics: lung, pregnancy,smoking, cervical lesions, anti La, childhood. https://t.co/QN4FVvQrYN
Sole RetamozoSole ( View Tweet)
Management of elderly patients with rheumatic diseases. Dr Rajasimhan. #ACR20 @RheumNow. Also we are near of first therapeutic recommendations of elderly #sjogren syndrome @ramos_casals @p_brito_zeron https://t.co/yjGrSTWV1K
Sole RetamozoSole ( View Tweet)
Editors Pick for #ACR20—Leflunomide–hydroxychloroquine combination therapy in patients with primary Sjögren's syndrome (RepurpSS-I): a placebo-controlled, double-blinded, randomised clinical trial https://t.co/cunDxVl5XG https://t.co/OGItXCuWDI
Links:
The Lancet Rheumatology TheLancetRheum ( View Tweet)
Lung disease in primary #SjogrensSyndrome is common; both conditions were diagnosed at the same time in 43% of patients, found an #ACR20 study from @joannamarco @GGRheumdoc + @UW @uofcincy colleagues. “Close monitoring is warranted” to make sure lung function is not declining. https://t.co/MpA0Rq2uVR
CreakyJoints.org CreakyJoints ( View Tweet)
Hand OA Rx strikes out. HCQ Rx neg and colchicine Trial negative. I wouldn’t put hand OA as same category of no Rx as for SSc and Sjogrens but agree though nuts to crack @eular_org @CRASCRRheum @earlyarthritis #EULAR2020 https://t.co/QRe3UpKpbz
Janet Pope Janetbirdope ( View Tweet)
#EULAR2020 OP0096 Dr. L Chatzis study on Sjogren:
1. 2nd most common autoimm dz in women
2. women:men ratio 20:1 (not 9:1)
3. 2 types Ro-Ab: nuc. Ro60 (assc w/La)and cytopls. Ro52 (assc w/ILD/myositis)
4. Seroneg. Sjogren's (neg Ro/La/RF) good prognosis:⬇️lymphoma
@RheumNow https://t.co/fV3ltQqnkf
k dao KDAO2011 ( View Tweet)
Primary Sjogren’s syndrome showed benefit of leflunomide + #Hydroxychloroquine vs placebo - past neg RCT of HCQ for PSS Sicca (dry eyes/mouth) so is it just leflunomide that works or combo? Likely pt selection - arthritis and rash likely respond to either @RheumNow @CRASCRRheum https://t.co/lsIeG2uv2H
Janet Pope Janetbirdope ( View Tweet)
