Article
You’ve scheduled an appointment with your medical provider - how do you make the most of it? We've gathered these tips and suggestions to share with patients.
All News
Article
Dr. Jack Cush reviews the news, journal reports, FDA actions, new side effects and changing prevalence of Gout.
Article
A new review article from CreakyJoints finds that there has been limited progress in understanding the potential of cannabis based therapies for the treatment of pain associated with rheumatic conditions in the past five years because of a lack of standardization of clinical research and barriers to conducting research due to existing federal and state regulations.
Dr. John Cush
Tweet
Evobrutinib, selective oral BTK inhibitor, has been studied in >1083 pts in phase 3 RCTs of RA, SLE, MS; shows well tolerated, most common AE ≥5% UTI (9.5%), nasopharyngitis (7.3%), diarrhea (6.2%), transient ^LFTs, SIE rate 2.72/100 PYs https://t.co/NTKYOAHhln https://t.co/oUKCDicjyA
Dr. John Cush
Tweet
TLR7 signaling impt to SLE as it drives type I IFN & activation of autoreactive B cells. Nature reports missense TLR7 (Y264H) variant from severe lupus induces guanosine & cGMP & causes murine lupus when introduced into mice. https://t.co/VZioZfcJQ6 https://t.co/AtxWD4XGBF
Dr. John Cush
Tweet
Dr. Judith James on environmental factors that contribute to lupus risk and expression. #UTSWSLE2022 https://t.co/MGE51vlDMY
Dr. John Cush
Tweet
RBCs from SLE patients retain mitochondrial proteins that may either lead to type I IFN or be taken up by myeloid cells. (V. Pascual) #UTSWSLE2022 https://t.co/VdQGRDUMvX
Dr. John Cush
Tweet
Dr. Pascual shows that signatures show IFN or plasmablast or PMN/Myeloid signatures, thus identifying 7 subsets of lupus kids #UTSWSLE2022 https://t.co/3BAxPdAKw8
Dr. John Cush
Tweet
Clinical evidence of type I IFNa excess expressed in clinical SLE (Dr. Virginia Pascual) #UTSWSLE2022 https://t.co/To2U9ZtxU3
Dr. John Cush
Tweet
Professor Chandra Mohan on pathogenesis and immunogenetics of #SLE - over 180 genes linked to the pathogenesis, modified by infection (bigger role for EBV?) hormones, smoking, hormonal status. #UTSWSLE2022 https://t.co/aKNpxZfdc6
Dr. John Cush
Tweet
Three (3) Worst Drugs to use in #Lupus patients who want to be pregnant (MTX, MMF, CTX) #UTSWSLE2022 https://t.co/YBeLTuRLO1
Dr. John Cush
Tweet
Algorithmic approach to SLE and assessing/treating early pregnancy. #UTSWSLE2022 https://t.co/692el4R9sZ
Dr. John Cush
Tweet
Adverse pregnancy outcomes and Risks in #SLE. (Dr. Eliza Chakravarty - OMRF) #UTSWSLE2022 https://t.co/HqscJD2m96
Dr. John Cush
Tweet
Long acting reversible contraceptives (LARC) are recommended in #SLE. #UTSWSLE2022 https://t.co/oFyNTHzVAj
Dr. John Cush
Tweet
Nearly 40% of all #SLE pregnancies are unplanned - hence, contraception (unused in 73%) and education are paramount in management of women w/ SLE. (Dr. Lisa Sammaritano- HSS) #UTSWSLE2022 https://t.co/ooryrW9GGn
Dr. John Cush
Tweet
"I think we can get rid of maintenance prednisone in nonrenal lupus" (but not in renal lupus)
"...prednisone contributes to some organ damage (but not renal)"
Organ damage is multifactorial -traditional risk factors, disease activity & steroids
- Dr. Michelle Petri #UTSWSLE2022 https://t.co/N9NMPgtPEn
Dr. John Cush
Tweet
From the Hopkins Lupus cohort - Just one month of Prednisone 40 mg/d yields a FOUR fold increase in avascular necrosis risk #UTSWSLE2022 https://t.co/RGP06PUIKH
Dr. John Cush
Tweet
UT Southwestern Symposia on "Future of SLE". Summary of Disparities in SLE Care/Outcomes (from Dr. Candace Feldman - Harvard). #UTSWSLE2022 https://t.co/KQb9JV7uJU
Dr. John Cush
Tweet
How do we solve/address the problem of Health Disparities in Lupus and Rheumatology? Dr. Ashira D Blazer, MD @ashira_md (HSS) approach:
Study
Listen
Educate
Partner
Diversity
#UTSWSLE2022 https://t.co/w3DX1w0chy
Dr. John Cush
Tweet
There is 1.4 million transgender persons in the US. ACP has published a guideline "Care of the Transgender Patient" addressing health disparities, certain cancers, substance abuse, mental health conditions, infections, and chronic diseases. https://t.co/AoBeOzv9YH https://t.co/jKabVELPxH
