Maeve Gamble
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How to switch from MMF to AZA for pregnancy:
#ACR19 @rheumnow #pregnancy #lupus https://t.co/er4CvIkOBQ
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Philip Robinson
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A small New Zealand study (n=50) gave different doses of tart cherry concentrate and assessed its effect on serum urate over 28 days. No effect was found. We shouldn't be emphasising dietary changes in gout patients - no evidence of efficacy #ACR19 @RheumNow #gout https://t.co/OamMPMHw0C
Maeve Gamble
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Abstr#548: Efficacy and safety of subcut CT-P13 (IFX biosimilar) 1 year after switching from IV CT-P13 in pts with RA. Non-inferiority of efficacy (decrease in baseline DAS28-CRP) at wk 22 achieved. Safety same. Another alt convenient way of administration? #ACR2019 @RheumNow
David Liew
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Basic truths of irAEs:
Symptoms do not equal irAEs, in diarrhoea/colitis as in arthralgias/arthritis. Substantial proportion excluded on investigation
Local site Rx where possible: because they often work, and systemic steroids still can’t be exonerated
#ACR19 @RheumNow https://t.co/TJHQkKcvX8
David Liew
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Normal inflamm markers in PMR: 14% (62/454) of the Nijmegen PMR cohort fell in this group, and they had similar rates of follow-up, steroid dependence, even similar rates of GCA (albeit low). A subgroup of PMR we need to understand better!
Diane Marsman #ACR19 ABST0759 @RheumNow https://t.co/XS2bPrWKUf
David Liew
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One of the hardest things about PMR is getting a reliable diagnosis - no biomarker and no histopath. Imaging has potential, and my colleague @drceowen has made a simple algorithm for reliable/replicable PET/CT dx 👍
@DrCMcMaster @jlyleung @Austin_Health #ACR19 ABST0755 @RheumNow https://t.co/JGswa6Wjju
Dr. Antoni Chan
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The C-AxSpand study, Certolizumab-treated nr-axSpA pts with shorter symptom duration (< 5 vs ≥ 5 years) showed greater improvements across signs and symptoms of disease and in quality of life. Kay J et al #ACR19 @RheumNow
Dr Irwin Lim
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REDO trial: ultra low dose Rituximab for RA
500mg x 1 or 200mg x 1 compared against 1000mg
6mo non-inferiority
Could not formally show this but for many, ultra-low doses appeared effective
Should lead to longer term & tapering studies
#ACR19 @rheumnow Abst0931
Dr. Antoni Chan
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A Phase 2b study demonstrated the sustained efficacy of bimekizumab in pts with active AS to Week 48. Bimekizumab was generally well tolerated and no new or unexpected safety findings were identified #ACR19 @RheumNow
David Liew
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You can treat all of the Hep C all of the time - but you won’t get rid of related cryoglobulinaemic vasculitis >10% of the time.
SVR with DAA in HCV does not equal vasculitis cured!
(PS you can even get it de novo after SVR)
n=1019 Egypt, France, Italy
#ACR19 ABST0948 @RheumNow https://t.co/Lp3ZVMwTgj
Dr Irwin Lim
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Here is result to save you looking it up in this highly refractory group
#ACR19 @rheumnow Abst0930 https://t.co/gYv7CZcMvL https://t.co/ToIavKEn4z
Dr. Paul Sufka
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Abstr# L14: data shows that in PsA you’re able to withdrawal MTX from the combo of tofacitinib+MTX without any loss of efficacy. Great news, because pts really like to minimize their meds when possible. #ACR19 @rheumnow https://t.co/3cDoTc1gWB
Olga Petryna
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@RheumNow #ACR2019 ABS899 Tart cherry concentrate had NO effect on serum urate, urine urate excretion or the frequency of gout flares over 28-day study period (p=0.76). However, those receiving allopurinol had significantly greater increases in urinary anthocyanins (p< 001) https://t.co/JJm9RCILoH
Jonathan Hausmann MD
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The amazing @GrantSchulert helps us begin to understand sJIA-associated lung disease #ACR19 @rheumnow #Abstr #ACRBest https://t.co/NGnjEYDBnL
Dr Irwin Lim
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How would vagus nerve stimulation help Rheumatoid Arthritis??
#ACR19 @rheumnow Abst0930 https://t.co/NupaKJkXCL
Dr. Antoni Chan
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The C-VIEW open-label study found a significant reduction in the AAU flare rate in axSpA pts with a history of recurrent AAU during the first 48 wks of Certolizumab. Pts also experienced significant improvement in axSpA disease activity #ACR19 @RheumNow
Olga Petryna
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@RheumNow #ACR19 ABS377 Stanford Univ retrosp stdy of pts w/ cardiac sarcoidosis supports use of TNFi in pts who failed cDMARs. Pts were able to reduce steroids dose w/no decline in LVEF in pts with preexisting CHF. larger, prospect studies needed
Dr Irwin Lim
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This is the device they used for the vagus nerve stimulation
#ACR19 @rheumnow Abst0930 https://t.co/XGKRjONTqf
Dr. Antoni Chan
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2 papers looking at TNFi on radiographic progression in Ankylosing Spondylitis. TNF inhibitor treatment slowed radiologic progression when compared to other therapies but covariables such as smoking and NSAIDs need to be considered #ACR19 @RheumNow
Dr Irwin Lim
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Filgotinib in RA (FINCH3); Another👍🏼 result for JAKi
How will we choose which JAKi to use in an increasing crowded space? Any thoughts?
#ACR19 @rheumnow Abst0927
