Calculating Serious Infection Risk in IMID Patients

Save

Predictive modeling of data derived from the DANBIO registry (of treated IMID patients) revealed a 4 fold increased risk of serious infection (SIE) in those starting biologic DMARD (bDMARD) treatment. From this large dataset, researchers developed a simple prediction model to estimate future infection risk that may inform shared decision-making in individual patients.

JAK Inhibitor Misses Endpoint in Safety Study. Now What?

Save

Pfizer announced results Wednesday from its FDA-mandated postmarketing safety study of tofacitinib (Xeljanz), and they don't bode well for the drug and possibly others in its class.

The risk of RA was studied in cohort of 14,463 endometriosis pts. RA risk was higher in those w/ endometriosis [adjusted HR 1.75), and also w/ age ≥45 years (adj HR 1.50) or with autoimmune disease (adj HR 6.99). https://t.co/sPouzyFI3H https://t.co/lDjSgLxXfV

Mortality Risk in Rheumatoid Lung Patients

Save

A Medicare claims analysis of rheumatoid arthritis (RA) patients showed that RA-associated interstitial lung disease (RA-ILD) was seen in nearly 5% of patients and was found to increase mortality risks, including respiratory and cancer mortality not explained by other factors.