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Monitoring Infliximab Drug Levels Improves Efficacy

Robert Chao, MD

Should we start considering therapeutic drug monitoring when prescribing TNFi for treatment of our rheumatologic conditions?

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FDA Puts Boxed Warnings on JAK Inhibitors

Jack Cush, MD

Based on the safety review of tofacitinib in Pfizer's Oral Surveillance (1133) study, the FDA has added serious boxed warnings to all three marketed JAK inhibitors (for inflammatory diseases) and formalized the recommendation that patients should be started on a TNF inhibitor (TNFi) before trying a JAK inhibitor. These recommendations apply to tofacitinib, baricitinib and upadacitinib.

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Rheumatoid Arthritis, Dementia and Cognitive Dysfunction

Jack Cush, MD

Rheumatoid arthritis (RA) has been linked to a higher risk of dementia and cognitive dysfunction, but interestingly this association has diminished in the last few decades with aggressive DMARD and targeted therapies..

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Methotrexate and hepatic fibrosis: we must be doing something right

David Liew, FRACP

Methotrexate may be a rheumatologist’s best friend, but a key part of counselling any patient about its use has always been the risk of hepatotoxicity.

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Prolonging the Controversy of Hydroxychloroquine

Kathryn H. Dao, M.D.

Since the start of the pandemic, hydroxychloroquine (HCQ) was forced into the limelight for the prevention/treatment of COVID-19. When it was found to be ineffective for COVID-19 and might cause potential harm, the drug came under closer scrutiny for its safety profile.

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RheumNow Podcast - 60/40/20 Interview with Dr. Ed Keystone

Jack Cush, MD

Dr. Jack Cush interviews Professor Edward Keystone, MD (University of Toronto) on the origins and science behind the 60/40/20 benchmark and outcomes in rheumatoid arthritis.


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Better assessment and management of multimorbidity

Mrinalini Dey, MD

Appropriate assessment and management of comorbidities and multimorbidity in patients with RA is vital for overall health and well-being of the patient, as well as to encourage treatment adherence, and address social, psychological and quality of life factors. 

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What are the advantages and disadvantages of #ultrasound-guided intra-articular injections? Check out this slide👇from Lt.Col/Dr. Arjun's lecture: #iracon21 #IRACON2021 @2021Iracon @APLAR_org #mskus #rheumatology https://t.co/mhq9OgBk7a
sheila RHEUMarampa ( View Tweet)

Download Available! AOSD Disease Patterns Over Time https://t.co/qZBtCQ2QAg https://t.co/fMmN1PAzFG

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Dr. John Cush RheumNow ( View Tweet)
Watch Now: Can We Stop Medication in Systemic JIA? https://t.co/yRIb70YVME https://t.co/EJ2PmC6xKY

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Dr. John Cush RheumNow ( View Tweet)
Rheumatoid arthritis (RA) has been linked to a higher risk of dementia and cognitive dysfunction, but interestingly this association has diminished in the last few decades with aggressive DMARD and targeted therapies. https://t.co/T1feTkSKQv https://t.co/XElvgsGC0E

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Dr. John Cush RheumNow ( View Tweet)
Might Tofacitinib Reduce Malignancy Risk with Patients with RA? https://t.co/xDnbPvjFDj https://t.co/yVcftm9Vwz

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Dr. John Cush RheumNow ( View Tweet)
Air pollution may induce #RA flares. A Verona, Italy study of 888 pts correlated pollutants to abnormal CRP levels - Pts exposed to greater air pollutant leveles had higher risk of CRP levels ≥5 mg/l; air pollutants were higher in 60d prior to RA flares https://t.co/2ICHdxbqGS https://t.co/QGq6mQals7

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Dr. John Cush RheumNow ( View Tweet)
Pregnancy Outcomes in PsA, SpA, RA: Dr. Rachel Tate ( @uptoTate) reviews abstracts #0369, #1722 and #1730 presented at the ACR21 annual meeting. https://t.co/kUQReWtEdO https://t.co/MZ9Fe1Ms3N

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Dr. John Cush RheumNow ( View Tweet)
Dr. Jack Cush interviews Professor Edward Keystone, MD (University of Toronto) on the origins and science behind the 60/40/20 benchmark and outcomes in rheumatoid arthritis. https://t.co/Ve6zOQPxZJ https://t.co/8RuL2CCsOQ

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Dr. John Cush RheumNow ( View Tweet)
ICYMI:Food for Thought: "ITIS" Diet for Patients with Rheumatoid Arthritis: Dr. Akhil Sood ( @AkhilSoodMD) discusses abstract #1699 presented at the ACR21 annual meeting. https://t.co/bpQuzDGXCF https://t.co/9e2dYddsIx

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Dr. John Cush RheumNow ( View Tweet)
ICYMI: Drs. Jeffrey Sparks, Greg McDermott and Vanessa Kronzer discuss work in the area of respiratory disease in RA, mucosal paradigm, RA-ILD, bronchiectasis, as well as their experience as virtual attendees at the #ACR21 annual meeting. https://t.co/5BrxeJBWM2 https://t.co/m8CqyJ1L7A

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Dr. John Cush RheumNow ( View Tweet)
ICYMI: Does Control of Inflammation Lower Cancer Risk? https://t.co/OBMIdPki7O https://t.co/zV04iAOjAz

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Dr. John Cush RheumNow ( View Tweet)
ICYMI: Multimorbidity, the presence of multiple overlapping chronic comorbid conditions, is increasingly common at first presentation of rheumatoid arthritis (RA), increasing as a person gets older and/or during disease progression. https://t.co/CL2xEyjKmd https://t.co/inoyahbkM9

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Dr. John Cush RheumNow ( View Tweet)
Dr. Janet Pope and Dr. Jeffrey Sparks discuss the importance of lung and several lung-related abstracts presented at the ACR21 annual meeting. https://t.co/s5sl6tdKwP

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Dr. John Cush RheumNow ( View Tweet)

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