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Partial vs Total Knee Replacement: Is One Superior?
Patients with osteoarthritis (OA) primarily affecting only one knee joint compartment did just as well with partial knee replacement (PKR) as with total arthroplasty after 10 years in a randomized trial -- and maybe a little bit better. Final results of the landmark TOPKAT study indicated that rates of the most clinically important outcomes were nearly equal between the two procedures, according to David Beard, DPhil, GDPhys, MCSP, MSc, of the University of Oxford in England, and colleagues. These similarities included Oxford Knee Score (OKS) values both at year 10 and cumulatively during the entire follow-up period, as well as reoperations and revisions.
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Vitamin D and Lupus Outcomes (11.21.2025)
Dr. Jack Cush reviews the news and journal reports from this past week on RheumNow.com.
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Rheumatology Supply and Demand (2009 - 2024)
A retrospective review of US rheumatology manpower and training between 2009 and 2024 shows that US rheumatology training has become competitive with an increasing surplus of applicants compared to available training positions, which have also increased over time.
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2023 National Health Interview Survey studied arthritis-attributable work limitations (AAWL) in US adults (18-64 yrs) - it was 38.8% (unchanged from 2019). AAWL was higher in Hispanics (50%), American Indian/Alaska Natives (56%), & disabled (62%), & veterans (52%) https://t.co/sE3En74zfq
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JAMA review of Peripheral Neuropathy - affects ~ 1% of adults worldwide and may cause sensory, motor, and autonomic Sxs. Diabetes is the most common cause. 1st line Rxs include gabapentin, pregabalin, duloxetine, amitriptyline. (FOR AMA MEMBERS) https://t.co/sof15I1GpU https://t.co/PN0KMeUsGA
Dr. John Cush RheumNow ( View Tweet)
Partial vs Total Knee Replacement: Is One Superior?
Patients with osteoarthritis (OA) primarily affecting only one knee joint compartment did just as well with partial knee replacement (PKR) as with total arthroplasty after 10 years in a randomized trial -- and maybe a little https://t.co/abER7mS3QR
Dr. John Cush RheumNow ( View Tweet)
Retrospective analysis of 2614 FM pts in the Italian Fibromyalgia Registry underscores the seasonal changes in FM pain, w/ signif. differences in FM assessment tools WPI p=0.042 & FASmod p=0.037); these changes were only seen in female patients, not males https://t.co/LqXnTgGIMB https://t.co/ihw1yJqKLC
Dr. John Cush RheumNow ( View Tweet)
ILD in Patients with Connective Tissue Disease
Dr. Janet Pope reports on abstract 0154 (Incidence and Prevalence of Connective Tissue Diseases with Interstitial Lung Disease (CTD-ILD) in the United States) at #ACR25.
https://t.co/WrJhsMizwV https://t.co/rkFny5ZjZQ
Dr. John Cush RheumNow ( View Tweet)
RNL 25 Replay: Spondyloarthritis
Enjoy these excerpts from the RNL 2025 meeting, and join us for RNL 2026 in Dallas, TX - registration is now open! Visit https://t.co/o78Pc8LPsQ for complete details.
https://t.co/OuVLKKbA6U https://t.co/zPiuSH47Fg
Dr. John Cush RheumNow ( View Tweet)
A New Disease Activity Score for Antiphospholipid Syndrome?
APS is a systemic autoimmune disorder. It is characterised by the presence of antiphospholipid antibodies and a broad spectrum of clinical features, causing obstetric as well as thrombotic, microvascular and https://t.co/eouynDPLUX
Dr. John Cush RheumNow ( View Tweet)
In 2024, 77 pts referred to Rheum for possible PMR were ultimately Dx w/ B19 viral infx. 96% had arthralgia & 7% had PMR-like features (5/5 w/ BL shoulder/neck. prolonged AM stiff, fever & Hi CRP/ESR - none had hip pain. 4/5 were male, w/ mean age of 55 yrs. None were RF/CCP+ https://t.co/lIX4gDLjqd
Dr. John Cush RheumNow ( View Tweet)
New quadrivalent modRNA influenza vaccine is more efficacious than conventional inactivated quadrivalent influenza vaccine. Really interesting excited to see mRNA technology transforming therapies. https://t.co/ZM13ojQUCl
Alberta Hoi alberta_hoi ( View Tweet)
"Play the game for more than you can afford to lose... only then will you learn the game.”
- Winston Churchill
Dr. John Cush RheumNow ( View Tweet)
Did you miss RheumNow Live 2025? 👀
Don’t make the same mistake twice.
🔥 RNL 2026 Early Bird Registration is LIVE — now through Dec 1.
Where clinical science meets real-world rheum talk.
🎟️ https://t.co/zYYC2350tE https://t.co/uZUlqScSm5
Links:
Dr. John Cush RheumNow ( View Tweet)
RheumNow Live 2026
Rheumatologists don’t just attend #RheumNowLive — they shape it.
Join the conversation that defines our field.
🕓 Early Bird registration open through 12/1
👉 https://t.co/zYYC2350tE
#RheumTwitter #Rheumatology #CME #RNL2026 #MedTwitter #HCPcommunity https://t.co/ejOB2WmOiv
Links:
Dr. John Cush RheumNow ( View Tweet)
Seeking Musculoskeletal Care
A report entitled The Burden of Musculoskeletal Diseases in the United States (BMUS) was published by the USBJD with input from rheumatology, orthopedic surgery, physical medicine and rehabilitation regarding musculoskeletal care. https://t.co/KGYHrQYADE
Dr. John Cush RheumNow ( View Tweet)
Retrospective review of 113 AOSD pts, median age 45yrs, ferritin 4626 (IQR 1169–14,239). Advanced Rx (IVIG, IL-1, IL-6) required in 15 (13.3%), NOT predicted by ferritin levels, either measured continuously or by quartiles. Ferritin is not a reliable biomarker in AOSD. https://t.co/pHEPeIf9u2
Dr. John Cush RheumNow ( View Tweet)
PROSPERO meta-analysis shows an effect of diet on #RA risk. 8 independent studies (n=270,121) showed a reduced risk of incident RA with Anti-inflammatory (OR 0.56; 0.31–0.99), Mediterranean (OR 0.88; 0.78–0.99), and HEI (OR 0.60; 0.25–1.47), but not DASH diets https://t.co/Qr9lXWRAED
Dr. John Cush RheumNow ( View Tweet)
Can EMR Treatment Suggestions Improve Decision Making?
In a new study, researchers from Northwestern University and the University of Sydney identified a “sweet spot” in clinical decision-making. By presenting just the right number of treatment alternatives in the EHR system, https://t.co/X0eHDIk3Uw
Dr. John Cush RheumNow ( View Tweet)
In 2024, 77 pts referred to Rheum for possible PMR were ultimately Dx w/ B19 viral infx. 96% had arthralgia & 7% had PMR-like features (5/5 w/ BL shoulder/neck. prolonged AM stiff, fever & Hi CRP/ESR - none had hip pain. 4/5 were male, w/ mean age of 55 yrs. None were RF/CCP+ https://t.co/SsLVEyL8X8
Dr. John Cush RheumNow ( View Tweet)
