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LNK01001 12 mg or 24 mg BID to 24 weeks in moderate to severe RA achieved ACR 20 (91.1%, 90.7% respectively), were generally safe, well tolerated with most TEAEs being mild to moderate. Effect seen in Week 1. Wu C, Late breaking Abst#L09 #ACR23 @RheumNow https://t.co/M29LYtEs9I
Dr. Antoni Chan ( View Tweet)
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AutoAb and irAE?? Really only associated for thyroid dysfunction. For ICI-IA we need different bio markers #ACR23 https://t.co/Fc24y8TzJv
Laura Cappelli ( View Tweet)
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Congratulations to Mount Sinai medical student and mentee Celestine He, on being awarded a Rheumatology Research Foundation Medical Student Preceptorship Award. Very proud of you and your excellent work! 👏🏻👏🏻👏🏻
#ACR23 @celestinejhe @MSRheumatology @IcahnMountSinai https://t.co/F078eSnL9p
Chrisanna Dobrowolski ( View Tweet)
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Our collaborative study on nirmatrelvir-ritonavir (Paxlovid) virologic rebound is out in @AnnalsofIM @DrJLi @zach_wallace_md
-Paxlovid: 21% with rebound vs. 2% in untreated (OR 10)
https://t.co/RRDxerGdBy
Jeffrey Sparks MD MMSc jeffsparks ( View Tweet)
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US adults with #gout had higher 10-year all-cause mortality rates than those without
Premature mortality in gout
➡️Has not improved over time despite improved survival in the general population
➡️Worse among women
➡️Worse among Black individuals
#ACR23
👉🏽https://t.co/NDCIhKfCNL https://t.co/uKCswHKU0n
Dr Ai Lyn Tan DrAiLynTan ( View Tweet)
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Hanging w a super star ⭐️ @CCalabreseDO https://t.co/yDcAMAr24V
Leonard Calabrese LCalabreseDO ( View Tweet)
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It's the fab @AurelieRheumo 🎉 https://t.co/ywp9uPC5yl
Beth ( View Tweet)
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https://t.co/ft1wNmMxGx
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
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So great to see posters back at #ACR23 and interactions of #students and #mentors which can be career shaping. Data from #Alberta with a nearly 3K survey on #cannabis use in Pts with #rheumatic diseases studying the use as #Rx and #recreational @RheumNow #979, 980 https://t.co/xbVcK5HuRS
Janet Pope ( View Tweet)
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#Exercise reduces #pain in knee #osteoarthritis
▶️Improvement at weeks 6 & 12, sustained at week 18
#ACR23 poster 1990
👉🏽https://t.co/y4quoWG5Hi
by @ProfDeepakKumar et al https://t.co/zbf05FCLZ9
Dr Ai Lyn Tan DrAiLynTan ( View Tweet)
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#ACR23 Abs #L07 data do not support tapering of TNFi treatment among RA patients in sustained remission in 3 year study. https://t.co/d0ZBWDKZlB https://t.co/EdllyGUT1y
Dr. Rachel Tate ( View Tweet)
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Anyone have any insight on the number of missing virtual posters #ACR23 ? Is it simply that people did not submit one by the deadline?
Richard Conway ( View Tweet)
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Dr. Sadelain gives a tour-de-force CAR-T overview for the future. Questions around programming antigen sensitivity and the life span of therapy are just the tip of the iceberg. #ACR23 @RheumNow https://t.co/oLog0SiQoE
Dr. Rachel Tate ( View Tweet)
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Rx of #inflammatory #arthritis with #glucocorticoids doesn’t seem to affect outcomes in #malignancy treated with #checkpoint #inhibitors. Good news as new or flaring inflammatory arthritis as an irAE can be severe. #ACR23 @RheumNow @ACRheum #1055 @CanRIO_Tweets https://t.co/tFIPcQq2X6
Janet Pope ( View Tweet)
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Does clinical enthesitis correlate with ultrasound enthesitis in psoriatic pts?
52 wk study randomized to secukinumab or placebo found a long-term stable response of enthesitis control
BUT NO correlation between clinical & US enthesitis
@RheumNow #ACR23 Abs#2243 https://t.co/H7pESzYrNi
Robert B Chao, MD ( View Tweet)
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TM61 at #ACR23
23 yo M p/w ~3mo of sternal swelling
- US probable abscess, drained + multiple abx w/ no improvement
- XR R shoulder + L elbow nl but MRI abn
- MRI L elbow: possible osteomyelitis (OM)
- MRI R shoulder; clavicular osteolysis
- Bone Bx clavicle + L Ulna: Chronic… https://t.co/QkLV9ce7hs https://t.co/o8zfu59MRP
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
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Pain sensitization in #OA in the MOST study. Biomechanical forces- ground reaction forces may
Alter nociceptive signaling but was not associated with pain.
Walking evoked knee pain specifically tested - no diff @RheumNow #ACR23 https://t.co/G7TXuwJ2EQ
Bella Mehta bella_mehta ( View Tweet)
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Tapering ABA vs. stable dose ABA in RA
No diff in DAS28 remission at 2 years
But…
Only in patients receiving concomitant MTX
Those tapering ABA mono also experience higher functional important
Of note: not an RCT
@RheumNow #ACR23 ABST2542 https://t.co/yycCDTnRiF
Aurelie Najm ( View Tweet)
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#Lupus #nephritis - #inflammatory #fibrosis predicts #renal damage on #kidney #bx @ACRheum @RheumNow #ACR23 #2552 - similar in CRF from #Diabetes etc Biomarker is i-IFTA - same as other CRF diseases https://t.co/2LNn5Wn7rJ
Janet Pope ( View Tweet)
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How does CAR-T work and how many do we have? Dr. Sadelain details the history, manufacturing, and 6 currently FDA-approved CAR-T products. #ACR23 @RheumNow https://t.co/a4jGfhT8EU
Dr. Rachel Tate ( View Tweet)