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LLDAS: Predicting Pregnancy Outcomes

Sheila Reyes, MD

Pregnancy in SLE is a high risk situation and active disease can lead to fetal loss, pre-term birth, IUGR and neonatal lupus syndromes. In a study by Dr. Michelle Petri and colleagues, they evaluated whether the LLDAS at the start of pregnancy was predictive of pregnancy outcome.

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FDA Warning on NSAIDs in Pregnancy

FDA

The U.S. Food and Drug Administration announced today in a Drug Safety Communication that it is requiring labeling changes for nonsteroidal anti-inflammatory drugs (NSAIDs).

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RheumNow Podcast – Lupus Delights (9.18.20)

Jack Cush, MD

Dr Jack Cush reviews the news and journal reports from the past week on RheumNow.com:

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COVID-19 Risks in Pregnant Women

Jack Cush, MD

There has been little science or evidence regarding the effects of COVID-19 infection on pregnancy and vice versa; and now the recent MMWR addresses the subject with two new reports

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Read our summary of abstract 1770 on whether the LLDAS at the start of pregnancy was predictive of pregnancy outcome. #ACR20 https://t.co/Z6f0VdMZK3 https://t.co/56UJkXfrAc

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Dr. John Cush RheumNow ( View Tweet)
Read our summary of abstract 1770 on whether the LLDAS at the start of pregnancy was predictive of pregnancy outcome. #ACR20 https://t.co/gfl7hKMDbe https://t.co/nX1qb6zHGo

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Dr. John Cush RheumNow ( View Tweet)
Watch our video titled Pregnancy in Spondyloarthritis. Dr Richard Conway ( @RichardPAConway) interviews Dr. Sinead Maguire about abstract #1323 presented at the #ACR20 annual meeting. https://t.co/YyWOuiq3jn https://t.co/IdqfbeX8x7

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Dr. John Cush RheumNow ( View Tweet)
#ACRbest Largest to date cohort study of pregnancies in women w/ ILD showed no maternal deaths suggesting that women w/ ILD may not need to avoid conception or terminate pregnancies, but pts w/ severe ILD were at higher risk for poor pregnancy outcomes. #Abst1446 @RheumNow

Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)

@psufka @wendycostello2 @RheumNow I love seeing patients in person! However, being pregnant during COVID19 made me adjust my practice significantly (as we all did.) Watch https://t.co/99R5rPryui it helped me to visualize the PE in an entirely new way. @RheumNow

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Dr. Rachel Tate uptoTate ( View Tweet)

Very young rheum patients (<21 y.o) may have higher risk for preterm delivery compared to those 21-25 y.o Abstr#1762 #ACR20 @rheumnow https://t.co/NyLEan2sA1

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k dao KDAO2011 ( View Tweet)

The @rheum_covid experience with patients with rheumatic disease who are *pregnant* and get COVID-19 is being presented by Bonnie Bermas from UTSouthwestern #ACR20 Sunday 3pm Eastern https://t.co/eeKqMXgpFx

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Dr Philip Robinson philipcrobinson ( View Tweet)

When discussing pregnancy outcomes with your axSpA patients, do you address potential outcomes related to disease in addition to medication concerns? #ACR20 @RheumNow

Dr. Rachel Tate uptoTate ( View Tweet)

Adverse pregnancy outcomes risk factors in spondyloarthritis 1⃣Most common - GSA 2⃣IBD symptoms, aggressive/active disease ⬆️risk 3⃣No difference in age or steroid use Healthy mom, healthy baby. @RheumNow #ACR20 Abs#1324

Robert B Chao, MD doctorRBC ( View Tweet)

Pregnancy outcomes in women with AxSpA 4 prospective cohorts in Europe 328 total pregnancies Favorable outcomes overall 1⃣3% pre-eclampsia 2⃣6-9% gestational DM 3⃣0-5% preterm birth rates (similar to WHO rate 9% in Eur) @RheumNow #ACR20 Abs#1498

Robert B Chao, MD doctorRBC ( View Tweet)

#sjogren #syndrome poster session #ACR20 @RheumNow Clinical characteristics: lung, pregnancy,smoking, cervical lesions, anti La, childhood. https://t.co/QN4FVvQrYN
Sole RetamozoSole ( View Tweet)
How pregnancy impacts nr-axSpA disease activity can vary from one woman to another, according to Eric Ruderman, MD, “I’ve had some patients who are better during pregnancy, and some who aren’t,” says Dr. Ruderman. Learn more about pregnancy and nr-axSpA: https://t.co/mC6YcG5lIx

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NM Rheumatology NM_Rheumatology ( View Tweet)

RheumNow Podcast - ACR Reproductive Health Slides (9-11-20) Dr Jack Cush reviews the 2020 ACR Reproductive Health Guidelines This past week we presented an overview to the new 2020 ACR ACR 2020 Reproductive Guidelines - Contraception & Counseling https://t.co/vnPh2EQZ0a https://t.co/T4y69DYIH7

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Dr. John Cush RheumNow ( View Tweet)
Candian study of 376 pregnancies (284 F) with #SLE and drug use: only 24.2% on antimalarials, 8.2% azathioprine, 19.7% steroids &amp; 4.8% on NSAIDs during pregnancy. 1st trimester discontinuations seen in 16.7% of HCQ & 29.2% AZA https://t.co/a1SMwZuSlm

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Dr. John Cush RheumNow ( View Tweet)

Swedish registry comparison of 541 PsA 40944 non-PsA pregnancies between 1997-2014, shows PsA pregnancies had increased risks for preterm birth (adj OR 1.63) and caesarean deliveries (OR 1.47), but no increased risks for pre-eclampsia, stillbirth https://t.co/3Udpjhn1pe

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Dr. John Cush RheumNow ( View Tweet)

Discontinuing TNFi before wk 20 is feasible in RA and JIA pregnancy with well- controlled Dz. OTIS study of 490 women compared 25% who D/C TNFi before wk 20 vs 41% taking TNFi after wk 20. D/C TNF not assoc w/ clinical worsening in the 3rd trimester. https://t.co/DtHvQ2rbWY

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Dr. John Cush RheumNow ( View Tweet)

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