All News

Probenecid, an OAT3 inhibitor, has inhibitory effects on RNA viruses (influenza, RSV) & decreases ACE2 expression. May have utility in COVID-19 as it was shown to inhibit SARS-CoV-2 replication in animal models https://t.co/MClSjpqpSa

Links:

Dr. John Cush RheumNow ( View Tweet)

RheumNow Podcast square

RheumNow Podcast – High Science and Future Treatments (9.10.2021)

d Jack Cush, MD

This week: high science that affect future treatments; breakthrough infections in our patients, and what's up with that; and soon your radiologist is going to be replaced by AI. This and more in our review of the news and journal articles from the past week.

Read Article
Differential Dx of immune-mediated necrotizing myopathies (IMNM) - HMGCR & Signal recognition particle Abs; checkpoint inhibitors, anti-Mi2 dermatomyositis, antisynthetase syndr. antimitochondrial Abs, GVHD, SARS-CoV-2 infection https://t.co/hhizx5gAet

Links:

Dr. John Cush RheumNow ( View Tweet)

Analysis of records from the Mass General Brigham healthcare system in the Boston area, shows that breakthrough infections (after receiving SARS-CoV-2 vaccines) in patients with SARDs are not uncommon, and may be severe or fatal. https://t.co/Ri5QipR7YY https://t.co/TaTFTKfAzm

Links:

Dr. John Cush RheumNow ( View Tweet)
Confused by all the different types of #COVID 19 tests? They are broken down in an easy-to-use tool here: https://t.co/P5jHhnzFej #Antigen #Antibody #PCR @CreakyJoints @IFAiArthritis @US_Pain @IAFaccess @colorofcci @patientaccess @aimedalliance @patientsrising @AARDATweets

Links:

Lupus Association LADAOrg ( View Tweet)

3 of 4 COVID hospitalized in NJ are unvaccinated. - 5.6 mill fully Vax; 2.7 mill unvaccinated, - COVID hosp. rate of 4.33/100,000 fully vaccinated & 26.33/100,000 for unvaccinated. - Unvaccinated are nearly 6 times more likely to be COVID hospitalized https://t.co/nvDNODBlRW https://t.co/h3CcLXGLXG

Links:

Dr. John Cush RheumNow ( View Tweet)
Telephone survey of 278 Rheumatic Pts during COVID (July 2020) showed 22% reduced/interrupted treatments, only 11 (4%) stopped. Decisions made by half (49%). Stop Reasons: anxiety (48%), IV Rx access (45%), Rx unavailability (6.5%) https://t.co/XgJ1TJsHJG

Links:

Dr. John Cush RheumNow ( View Tweet)

Covid lung pneumonia corona (keep)

COVID Breakthrough Infections in Rheumatic Patients

d Jack Cush, MD

Analysis of records from the Mass General Brigham healthcare system in the Boston area, shows that breakthrough infections (after receiving SARS-CoV-2 vaccines) in patients with systemic autoimmune rheumatic diseases (SARDs) are not uncommon, and may be severe or fatal.

Read Article
What's your prediction when the Pandemic will end and we can travel, vacation, hug & handshake?

Dr. John Cush RheumNow ( View Tweet)

JAMA: In women with spontaneous abortions, COVID-19 vaccine exposure was not increased compared with women without Spont Ab (ongoing pregnancy). COVID-19 vax given to 8.0% ongoing pregnancy vs 8.6% spont ab (adj OR 1.02) https://t.co/wEeaMR98Mf

Links:

Dr. John Cush RheumNow ( View Tweet)

MMWR: COVID-19–hospitalization rates in kids & adolescents rose 5-fold late June–mid-Aug 2021 (w/ rise of Delta variant). Hospitalization rates were 10 times higher among unvaccinated than fully vaccinated adolescents. https://t.co/Qt5lj3Ycxb

Links:

Dr. John Cush RheumNow ( View Tweet)

In case you missed it— Booster Shots for Rheumatology Patients on Immunosuppressive Medications https://t.co/dIzrv3B12u https://t.co/nGIUNcqNTf

Links:

Dr. John Cush RheumNow ( View Tweet)
Our latest @MassGenBrigham rheumatology COVID collaboration with @zach_wallace_md #preprint to share quickly. 16 confirmed breakthrough infections in rheumatic patients since vaccine EUAs in US. 15 symptomatic, 6 hospitalized, 2 deaths https://t.co/atixfBcEbn

Links:

Jeffrey Sparks MD MMSc jeffsparks ( View Tweet)

Our @MassGenBrigham @zach_wallace_md rheum COVID paper on breakthrough infections is out now in ARD https://t.co/zOZqF0ecaG

Links:

Jeffrey Sparks MD MMSc jeffsparks ( View Tweet)

MMWR: COVID-19–hospitalization rates in kids & adolescents rose 5-fold late June–mid-Aug 2021 (w/ rise of Delta variant). Hospitalization rates were 10 times higher among unvaccinated than fully vaccinated adolescents. https://t.co/Qt5lj3Ycxb https://t.co/p2e0KoiAXr

Links:

Dr. John Cush RheumNow ( View Tweet)
Highly allergic can safely get the COVID Vax. Israeli study of 8102 pts w/ allergies recv Pfizer mRNA vax - 429 were highly allergic-->98% of the highly allergic had no allergic rxns, 1% mild allergic resp & 3 anaphylactic rxns Rx w/ EPI, none hospitalized https://t.co/ATYs5R5AQC https://t.co/owNEACH1pe

Links:

Dr. John Cush RheumNow ( View Tweet)
Not All Immunosuppression Alters Vaccine Immunogenicity https://t.co/I9sShpMLBO https://t.co/oz9Qp1HM1e

Links:

Dr. John Cush RheumNow ( View Tweet)
PhIII trial of Baricitinib vs placebo in hospitalized COVID-19 pts (91% steroids, 13% remdesivir). While no diff (28 vs 30%) in primary outcome (O2, ventilation, death). BARI had signif better Mortality @28d (8 vs 13%) & 60d (10 vs 15%) w/ no incr in VTE https://t.co/AjoRgEKW8G

Links:

Dr. John Cush RheumNow ( View Tweet)

syringe,needle,vaccine

Not All Immunosuppression Alters Vaccine Immunogenicity

d Jack Cush, MD

Chronic inflammatory disease (CID) patients are urged to receive the COVID-19 vaccines; but when a cohort of CID patients treated with immunosuppressive medications were given an mRNA-based SARS-CoV-2 vaccination, only those treated with glucocorticoids and B cell depleting therapies (B

Read Article
Lancet: 1276 Wuhan hosp COVID-19 pts studied at 6 & 12 mos. 68% & 49% had at least 1 COVID Sx at 6 & 12 mos. 12 mos sxs: SOB (30%), depression(26%), pain & mobility. Women had more fatigue/weak (OR 1.43), anx/depression (2·0), diffusion impairment (2·97) https://t.co/A8STTYiHq5 https://t.co/J4JoKFa00K

Links:

Dr. John Cush RheumNow ( View Tweet)

Do you get our email newsletter?

Looking for the latest rheumatology news & trends? Sign up for the RheumNow weekday newsletter:

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Rheumnow.com is a news source dedicated to the field of Rheumatology. It is written by experts in the field, and written for rheumatologists and individuals working in related fields. Rheumnow.com provides daily updates on the site and in your inbox when you are signed up for our newsletter.

Copyright 2024 All Rights Reserved.

×