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RheumNow Podcast – Quackademia (10.15.2021)

Jack Cush, MD

Dr. Jack Cush reviews the FDA approvals, news and the latest journal articles from the past week on RheumNow.com.

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morbidity,covid,heart,lung,brain

2021 Update to EULAR Points on Immunomodulatory Use in COVID-19

Jack Cush, MD

EULAR has updated its recommendations (points to consider - PtC) for rheumatologists managing patients during COVID-19; now with 2 overarching principles and 12 PtC.

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aosd.CXR_.jpg (keep)

Still’s Disease Following COVID-19 Vaccination

Jack Cush, MD

Both systemic onset juvenile idiopathic arthritis (sJIA) and adult-onset Still’s disease are acquired autoinflammatory disorders of uncertain etiology. Yet recent reports of AOSD onset and flare following COVID-19 vaccinations may have important mechanistic implications.

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RheumNow Podcast – #ACA: Ask Cush Anything (10.8.2021)

Jack Cush, MD

Arthritis numbers are rising, and people are finally talking about osteoarthritis. Also, ACR 2021 is just a few weeks away - are you ready? Finally, I'll review cases and questions submitted by viewers in Ask Cush Anything (#ACA). This, and nearly a dozen news items and reports, are discussed in this week's podcast. Let's begin.

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obesity,scale,weight

Obesity Rates Rise During the Pandemic

Jack Cush, MD

New data from the Centers for Disease Control and Prevention shows that obesity rates have risen in the USA during the pandemic. Sixteen states have obesity rates of 35% or higher - that's four more than last year, adding Delaware, Iowa, Ohio and Texas to the list.

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RheumNow Podcast – Jack of All Subspecialties (10.1.2021)

Jack Cush, MD

Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com

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vaccination

CDC Advises COVID-19 Vaccines for Pregnant Women

CDC

Today, CDC issued an urgent health advisory to increase COVID-19 vaccination among people who are pregnant, recently pregnant (including those who are lactating), who are trying to become pregnant now, or who might become pregnant in the future to prevent serious illness, deaths, and adverse

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In case you missed it… Still’s Disease Following COVID-19 Vaccination Read more on #RheumNow https://t.co/23R41Pydve https://t.co/a44cYIkc98

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Dr. John Cush RheumNow ( View Tweet)
For best practices in managing the Delta wave, the US would have done well to consult Puerto Rico US 26 cases/100,000 people, 19/100K hospitalized 57% vaccinated PR 3 cases/100,000 people, 3/100K hospitalized, 68% vaccinated https://t.co/kqlXBlmYpu
Eric Topol EricTopol ( View Tweet)
A case of reactive arthritis following COVID-19 infection; manifest as dactylitis, psoriatic skin/nail lesions, painful oral & vaginal ulcers, subungual hyperkeratosis, but no oligoarthritis, or lumbar pain. https://t.co/nobMHGgKfZ

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Dr. John Cush RheumNow ( View Tweet)

Could Auranofin work in COVID-19 infection? it may do so by inhibiting IL-6 production, as auranofin inhibits TLR3/TLR4, STAT3/JAK1 and thioredoxin reductase that regulates NF-kB (later IL-6); and may inhibit viral replication too. https://t.co/efLG4tzpTZ

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Dr. John Cush RheumNow ( View Tweet)

Anakinra appears to lower mortality risk (OR 0·32 vs historic controls) in hospitalized severe COVID-19 pneumonia (esp w/ hyperinflammation, CRP >100 mg/L). Metanalysis of nearly 2000 pts; better resp if given w/ dexamethasone (OR 0·23) https://t.co/7nFAkLgpGK

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Dr. John Cush RheumNow ( View Tweet)

WHO's Strategic Advisory Group on immunisation has advised an addition COVID vaccination in those >60 years and the immunosuppressed (due to a higher risk of breakthrough infections) https://t.co/NcGr8EMDaO

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Dr. John Cush RheumNow ( View Tweet)

SLE hospitalized with ARDS from COVID-19 have significantly higher risks of death and poor outcomes (RR=1.7), compared 319 SLE vs 251,800 nonSLE - SLE was more impactful than other comorbidities in such poor outcomes https://t.co/8VJjdOmTbi https://t.co/jYTg6k1QNq

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Dr. John Cush RheumNow ( View Tweet)
Study of 380 nonintubated severe COVID-19 pneumonia patients showed that those with the highest tertiles of FERRITIN (1322-13 ,418) showed significant reduction in mortality (HR, 0.16; 0.06-0.45) if given methylprednisolone [120-240] mg https://t.co/Jr1aWlPpOk

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Dr. John Cush RheumNow ( View Tweet)

ICYMI: New data from the CDC shows that obesity rates have risen in the USA during the pandemic, with 16 states having obesity rates of 35% or higher - that's four more than last year, adding Delaware, Iowa, Ohio and Texas to the list. https://t.co/9nFuea2BOV https://t.co/XmsXmFXhzv

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Dr. John Cush RheumNow ( View Tweet)
ICYMI: Can I get the INFLUENZA and COVID Vaccines together? The CDC says: "YES...both vaccines can be given at the same visit, people should follow the recommended schedule for either vaccine.... ideally get a flu vaccine by the end of October." https://t.co/T49zm6kWGE https://t.co/WQMx3XhHmL

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Dr. John Cush RheumNow ( View Tweet)
What will happen after COVID - more panic and neglect of public health? An interesting read from The Atlantic. “Progress is always undone; promise, always unfulfilled. “ Is America Prepared for the Pandemic After COVID-19? https://t.co/AA9qIo0DMH

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Dr. John Cush RheumNow ( View Tweet)

CDC Advises COVID-19 Vaccines for Pregnant Women https://t.co/cRQx8QdO7F #RheumNow https://t.co/iL6JIEiGFw

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Dr. John Cush RheumNow ( View Tweet)
Global SECURE-IBD trial on IBD drugs and COVID shows that severe COVID-19 outcomes were not associated with the use of biologics and mesalamine/sulfasalazine, AZA, 6MP, MTX combo Rx or biologics (TNFi, IL-12/23, IL-23, integrin inhib) https://t.co/MO4i5ngKkr

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Dr. John Cush RheumNow ( View Tweet)

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