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Crepitus Does Not Predict Earlier/Worse OA

EurekAlert!

Young adults who experience grinding or clicking sounds in their knees post-surgery may be alarmed, but new research from La Trobe University suggests these sounds may not signal early-onset osteoarthritis. 

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Osteoporosis in Older Men

Jack Cush, MD

JAMA has publish an invited commentary on Screening for Osteoporosis (OP) in Older Men. They point out that a simple screening strategy for older men based on previous fracture history and bone density screening at age 70 or 75 years is a reasonable means of screening for OP in older men.

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Osteoporosis Drug May Lower Osteoarthritis Risk

Jack Cush, MD

A target trial emulation study using administrative claims suggests that romosozumab was associated with a lower risk of osteoarthritis than teriparatide among individuals with osteoporosis, particularly for knee osteoarthritis.

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1 in 5 Patients are Unaware of their Arthritis Diagnosis

Jack Cush, MD

Current CDC numbers suggest that arthritis (any type) affects an estimated 67.1 million (27.9% ) adults in the USA.  Interestingly, 1 in 5 do not know their arthritis subtype (21.6%, 14.4 million).

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Osteoporosis treatment benefits people older than 80

EurekAlert!

People who are older than 80 should be considered for osteoporosis treatment after a fracture to avoid further risk, according to a study being presented Saturday at ENDO 2025, the Endocrine Society’s annual meeting in San Francisco, Calif.

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Simple Measures are Effective in Knee Osteoarthritis

EurekAlert!

Knee braces, water therapy and exercise are the most promising non-drug therapies for treating knee osteoarthritis, according to a new meta-analysis publishing June 18, 2025 in the open-access journal PLOS One by Yuan Luo of the First People’s Hospital of Neijiang, China.

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MTX Fails Knee OA (6.6.2025)

Jack Cush, MD

Dr. Jack Cush reviews the news and journal reports from this past week on RheumNow.com

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Dr. Josef Smolen discusses 2025 EULAR updates for RA. He highlighted the importance of OP A - that tx should be a shared decision making between px and rheuma in order to ensure better care and disease control. @RheumNow #aplar25 #APLAR25 https://t.co/KOJbiK87TS

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sheila RHEUMarampa ( View Tweet)
TriNetX database study shows Beta blocker use assoc w/ more hip replacements (THA). 23K propensity matched pts (mean age 69) on or off BB compared. After 3 yrs BB use was assoc w/ higher risk of THA (HR 1.49; 1.4–1.59), esp w/ alpha-BBs (HR 1.64) https://t.co/W6ocMYI653 https://t.co/EiQ4WH94cD

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Dr. John Cush RheumNow ( View Tweet)
Chondrocalcinosis Increases Osteoarthritis Risk Analysis of data from two large, prospective cohort studies show that knee chondrocalcinosis was associated with an increased risk of incident knee osteoarthritis. https://t.co/Jd1Wb9lWpT https://t.co/QwXn2ehNie

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Dr. John Cush RheumNow ( View Tweet)
Study of 110 #SLE pts found 41% w/ osteoporosis, 35% of whom had Lupus nephritis (LN). SLE w/ lower BMD assoc w/ LN classes III & IV, U1-RNP Abs, high CRP, & longer Dz duration, also w/ higher age, HAQ, C3 levels. 86% were on glucocorticoids, mean age 48 yrs. https://t.co/dqutqbvnjB
Dr. John Cush RheumNow ( View Tweet)
Mild cognitive impairment (MCI), (a reversible precursor to dementia) is increased in elderly RA (n=378) and is signif. assoc w/ course of disease(OR 1.07), DAS28 (OR 1.31), high CRP (OR 1.01) & osteoporosis (OR 1.88) as independent risk factors. https://t.co/45DY03sD23 https://t.co/kdX9TnykVK

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Dr. John Cush RheumNow ( View Tweet)
CKD & Osteoporosis Rx Revisited (7.25.2025) Dr. Jack Cush reviews the news, journal and FDA updates from this past week on RheumNow. https://t.co/k78DRpWIJS https://t.co/aYKvIhmJN1

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Dr. John Cush RheumNow ( View Tweet)
Osteoporosis Drug May Lower Osteoarthritis Risk A target trial emulation study using administrative claims suggests that romosozumab was associated with a lower risk of osteoarthritis than teriparatide among individuals with osteoporosis, particularly for knee osteoarthritis. https://t.co/fWWw2t2jzR
Dr. John Cush RheumNow ( View Tweet)
Osteoporosis treatment benefits people older than 80 People who are older than 80 should be considered for osteoporosis treatment after a fracture to avoid further risk, according to a study being presented Saturday at ENDO 2025, the Endocrine Society’s annual meeting in San https://t.co/ry3V4Nmq7E
Dr. John Cush RheumNow ( View Tweet)
Survey shows only 1% of men are concerned about bone density; but 2 million men have osteoporosis, and 16 million men have osteopenia. https://t.co/DA4vSmj0vd? https://t.co/V4OChN022V

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Dr. John Cush RheumNow ( View Tweet)
Intraarticular IL-1Ra Gene Therapy in Knee Osteoarthritis In a dose-escalation trial in nine participants, they observed that a single intra-articular injection of the gene product led to an increase in IL-1Ra in the synovial fluid that remained elevated for up to a year. There https://t.co/YDuUg44ebu
Dr. John Cush RheumNow ( View Tweet)
EULAR Classification criteria for hemachromatosis, presented by Prof. Kiely shows clinical pearls in diagnosis - Hook osteophytes @MCP 2/3, & Iron Fist sign w/ elevation of MCPs 2&3. #EULAR2025 https://t.co/S8iA0C4pwG
Dr. John Cush RheumNow ( View Tweet)
Using high-resolution peripheral quantitative computed tomography (HR-pQCT), patients with psoriatic arthritis (PsA) & psoriasis (PsO) show reduced cortical volumetric bone mineral density (vBMD) & thinner cortex vs controls. Bone mechanics impaired: reduced stiffness & failure https://t.co/ghH2cwOYJc

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Antoni Chan MD (Prof) synovialjoints ( View Tweet)
Denosumab and Osteoporosis - A JAMA Review An overview of denosumab use in osteoporosis (OP) by Bauer and Ensrud was published in JAMA https://t.co/3d7Q61nVKM https://t.co/i3DjtcsuWo

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Dr. John Cush RheumNow ( View Tweet)
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