Gout management has entered what Dr. Robert Terkeltaub MD from UC San Diego described as its “disease-modifying era,” during his talk at RheumNow Live 2026. In a recent comprehensive review of the past, present, and future of gout therapy, the central message was clear: “We can really apply disease modification to gout based on prospective, randomized controlled trials.”
All News
Article
Article
Dr. Jack Cush reviews the hot item takeaways from last week's RheumNow.Live 2026.
RT @gibson_RheumPAC
Axial PsA remains an area of active investigation. IL-17 inhibitors show consistent benefit, while IL-23 data are emerging—highlighting nuances when axial symptoms drive treatment choice. #RNL26 https://t.co/XFL3Sf8iK4
RT @Gibson_RheumPAC
A good reminder: PsA treatment should be domain-based. Skin, peripheral joints, axial disease, and enthesitis may each favor different pathways. #RNL26 https://t.co/IUCsdlNopo
RT @ericdeinMD
#RNL26
GLP on Knee OA
STEP 9 Trial - 68 wk
Mean WOMAC improved by 41.7 pts, compared to 27.5 in PBO, improved SF-36
7% stopped due to side effects https://t.co/LJzGzzlgq6 https://t.co/5ybyUdfNjZ
RT @Gibson_RheumPAC
Important rheumatology signal: dupilumab-associated inflammatory arthritis. Usually seronegative, imaging-supported, and sometimes persistent despite normal labs. Co-management and careful work-up are essential.#RNL26 https://t.co/r73cSZC59s
Incretins/GLP-1s are being investigated widely. @RWCSmtg #RWCS26 https://t.co/57JzRJfK8l
Most inhibition of inflammation is via the brain. More GLP1 and GIP1 receptors are in the brain, more than the gut. @RWCSmtg #RWCS26 https://t.co/CNzUqteBLg
The hx and timeline of GLP1a development. @RWCSmtg #RWCS26 https://t.co/7tPgcRy4Ze
Dr. Willa Tsueh taking on hx of GLP-1 agonists. The first ones, Victoza and Tulicity go back to 2010. @RWCSmtg #RWCS26 https://t.co/cKiDCM5xw6
#RNL26
Haque @HopkinsRheum
1/2 of Americans will be obese by 2030
"Obesity is common & obesity is expensive"
Adipose tissue - active endocrine organ -> cytokines, chemokines, adipokines
Leads to inflamm axis - risk factor similar to 🚬, higher activity, worse response https://t.co/yQLTpE7reY
RT @ericdeinMD
#RNL26
Dx Modification of OA
@Tuhina_Neogi
Challenge in drug develop:
Models in young animal, not like human OA
Trial enrollment in pts w late, establ OA- not early interv tx
Many paths to OA - target mechanism to correct pt
Slow progress of dx, $$
Endpt? Sx or
Vasculitis
Sunday’s vasculitis session at RNL26 was a fantastic update on inflamed blood vessels, large and small, by two experts in the field.
https://t.co/ueg3yJDMu4 https://t.co/8uiI9A5G8x
RT @Gibson_RheumPAC
GLP-1 receptor agonists do more than promote weight loss.
They impact insulin resistance, inflammation, cardiovascular risk—and may influence musculoskeletal disease. #RNL26 https://t.co/ypKnOJojAm
Staying Ahead of Spondyloarthritis
The diagnosis and treatment of spondyloarthritis can present challenging clinical scenarios for rheumatologists. At RheumNow Live, Pod IV focused on "Staying Ahead of Spondyloarthritis."
https://t.co/hZeqYC7wi3 https://t.co/2eKEueAukY
RT @Gibson_RheumPAC
Nearly 50% of U.S. adults may meet criteria for obesity by 2030.
For rheumatologists, it directly impacts disease activity, outcomes, and treatment response. #RNL26 https://t.co/cpy4LBBPHc
RT @gibson_RheumPAC
Osteoarthritis affects 600 million people worldwide—yet we still have no approved disease-modifying therapies.
A powerful opening to this talk on why OA drug development keeps missing the mark. https://t.co/wBUN3lux6X
