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Key points from #EULAR2023 on how to manage SLE
@RheumNow https://t.co/vJy7Cg7w8N
David Liew drdavidliew ( View Tweet)

Late Breaker - EULAR 2023 update on imaging of large vessel vasculitis. Ultrasound is now recommended as first line imaging test in all patients with suspected GCA, and axillary arteries should be in the standard examination, Dejaco C et al, Abst#LB0009, #EULAR2023 @RheumNow https://t.co/ya41nJG6qK
Dr. Antoni Chan synovialjoints ( View Tweet)

#ClinicalPearl This is cool - think of SGLT2 for #lupus #nephritis? presented at #SLE recommendations @RheumNow #EULAR2023 @eular_org https://t.co/8mbNt2n64v
Janet Pope Janetbirdope ( View Tweet)

#SLE #EULAR recommendations What is new - use LESS #glucocorticoids, aim for none or 5 mg/d or less, use #biologics early if needed to prevent damage, #lupus #nephritis consider less pulse dose if using, voclosporin vs Belimumab ? it depends @RheumNow #EULAR2023 https://t.co/Ylnnl3pHOK
Janet Pope Janetbirdope ( View Tweet)

Late Breaker - Cardiorespiratory fitness increased in patients with IJD after 12 weeks of supervised
HIIT and effect maintained at 6 months. No significant differences in pain and fatigue vs control. HIIT is a viable intervention Norden K Abst#LB0007 #EULAR2023 @RheumNow
Dr. Antoni Chan synovialjoints ( View Tweet)

Diagnostic delay in #lupus is really prevalent!
#EULAR2023 @RheumNow
20% with new lupus diagnosis are hospitalized!
20% diagnosis is delayed for more than 3 months! https://t.co/1vCcezBrQS
Bella Mehta bella_mehta ( View Tweet)

2023 @eular_org recommendations for LVV imaging
interestingly, the key changes vs 2018 are about PET/CT:
- can consider PET/CT for cranial GCA diagnosis
- PET/CT (alt MRI) can be used for monitoring - more for when you lose ESR/CRP because of IL-6i
#EULAR2023 @RheumNow https://t.co/2DC37CM6gA
David Liew drdavidliew ( View Tweet)

Meds in #lupus at #EULAR2023 recs
- HCQ first line therapy. Target dose remains the same. Some discussion on monitoring levels if possible
- MAIN CHANGE - Glucocorticoids to be minimized (only use for bridging). Nephrologists more so in favor of steroid free remission @RheumNow https://t.co/d8WnUOgrwq
Bella Mehta bella_mehta ( View Tweet)

Scleroderma therapeutics: we’re actually getting some choices!
Christian Dejaco #EULAR2023 @RheumNow https://t.co/sW2FBY0RqS
David Liew drdavidliew ( View Tweet)

JaL1/TYK2 inhibitor vs Tofacitinib in #RA at #EULAR2023 phase 2. @RheumNow https://t.co/0F3JQ9dVMA
Bella Mehta bella_mehta ( View Tweet)

Abstracts talking about #RA and JAKs and Biologic comparisons
Huge number of pts to analyze this aftrr the initial NEJM study. Abstract summary pics below
@RheumNow https://t.co/jl5S4fLq19
Bella Mehta bella_mehta ( View Tweet)

Abatacept in pts at risk of #RA data from clinical trial.
213 pts, 31 centers.
Pts with multiple autoantibodies improved the most with abatacept.
@rheumnow #EULAR2023 https://t.co/c82jx0cAEq
Bella Mehta bella_mehta ( View Tweet)

Central sensitization of neuropathic pain in #PsA - patient reported outcomes.
114 pts. And 22 percent with fibromyalgia
Pts with neuropathic pain didnt reach low disease activity or remission.
@RheumNow #EULAR2023 highlights! https://t.co/Gxkcrruamp
Bella Mehta bella_mehta ( View Tweet)

MmF and Tacrolimus both work in systemic sclerosis with ILD. @RheumNow #EULAR2023 https://t.co/Ro6AjP3nij
Bella Mehta bella_mehta ( View Tweet)

2023 update @EULAR recommendations imaging in GCA
What's new:
1. US = first line imaging test
2. Axillary arteries should be included in standard examination
3. Alternative imaging FDG-PET or MRI
4. Takayasu: MRI preferred CT or FDG-PET alternatives
@Rheumnow #EULAR23 LB0008 https://t.co/rGPfOPX1gI
Aurelie Najm AurelieRheumo ( View Tweet)

CAR-T cells in refarctory SLE- long term data presented #EULAR2023
Pts did well except some mild cytopenias. Pts remained in remission.
Maybe a good option in the near future for refractory pts!
@RheumNow https://t.co/NWoFBipOiQ
Bella Mehta bella_mehta ( View Tweet)

#EULAR2023 Clinical Highlights. CTD: OP0240 Open label study (N=26) showed stabilisation/improvement in FVC in patients with #ILD treated either Tacrolimus vs MMF. No efficacy difference between both therapies @RheumNow https://t.co/d3rCzNgYHK
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)

Microvascular visualization in Behcet's disease by ultrasound. Maybe really useful in cases which are difficult to diagnose and may not need biopsies in some pts.
#EULAR2023 @RheumNow https://t.co/PbC3tCe7v6
Bella Mehta bella_mehta ( View Tweet)

Denosumab in hand OA prevented erosions!
#eular2023 @RheumNow https://t.co/Ij2CVjh1ET
Bella Mehta bella_mehta ( View Tweet)

New treatment target for #gout
#EULAR2023
SEL-212 - 2 drugs one after the other!
- tolerogenic nanoparticles containing rapamycin followed by pegadricase
-only 50% reponded, but there were pts who didn't respond at all.
@RheumNow https://t.co/RXK58piU85
Bella Mehta bella_mehta ( View Tweet)