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Best of 2020: Rheumatic Disease Drugs and COVID-19

Jack Cush, MD

We are in the early stages of trying to limit the morbid and mortal consequences of the corona virus pandemic of 2020. Not surprisingly, the recommendations designed to limit exposure and damage continually highlight the fact that the elderly and immunosuppressed may be amongst the most severely affected should they become infected with this virus.

This has led to a great deal of uncertainty by patients and providers about how rheumatic diseases and their treatments need to be specifically addressed.

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Best of 2020: The Nine Lives of Hydroxychloroquine (Updated)

Martin J. Bergman, MD

Hydroxychloroquine is one of many medications frequently used in rheumatology practice. Its remarkable versatility is attested by its routine use in lupus, in patients with an autoimmune coagulopathy, in patients with rheumatoid arthritis, as well as in those with a low-level inflammatory arthropathy.

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ACIP Recommendations for Pfizer-BioNTech COVID-19 Vaccine Use (including Special Populations)

CDC/MMWR

Following the FDA issuance of an Emergency Use Authorization for the Pfizer-BioNTech COVID-19 vaccine, the Advisory Committee on Immunization Practices (ACIP) issued interim recommendations for the prevention of COVID-19 in persons aged ≥16 years. 

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COVID-19 as a Leading Cause of Death in the USA

Jack Cush, MD

The exponential rise in deaths from the coronavirus (COVID-19) in the last several months is put into perspective by JAMA Viewpoint article noting that current US death rates of > 3000 per day from COVID-19 is greater than that seen in one day on September 11, 2001 (9/11 attacks, claimed 2988 lives) or by a fictional catastrophe of 15 Airbus 320 jetliners (150 passengers each) crashing daily.

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COVID Risks in Systemic Autoimmune Patients

Jack Cush, MD

There have been conflicting reports of whether rheumatic patients have greater risks once they are infected with COVID-19. This claims cohort analysis suggests a mixed picture. 

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#BestACR20Tweets RT @jeffsparks :Important results from @kmdsilvaMD (newly funded by @RheumResearch): rheumatic patients with COVID with higher risk of hospitalization, ICU admission, CHF, AKI, and VTE than matched comparators. @zach_wallace_md https://t.co/bmuPBf89xD https://t.co/njHYkbenjy

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Dr. John Cush RheumNow ( View Tweet)
FDA issues emergency use authorization (EUA) for the 2nd COVID-19 vaccine from MODERNA. “With the availability of 2 vaccines now for the prevention of COVID-19, the FDA has taken another crucial step in the fight against this global pandemic..." https://t.co/AnmwOZtALk

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Dr. John Cush RheumNow ( View Tweet)

ACIP Recommendations for Pfizer-BioNTech COVID-19 Vaccine Use (including Special Populations) https://t.co/Q15gQRWGhg https://t.co/Jk1PbRzMtT

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Dr. John Cush RheumNow ( View Tweet)
New podcast up! COVID Vaccine Q & A - Dr Kevin Winthrop https://t.co/EJL6hVLnrp https://t.co/3oriO09PBU

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Dr. John Cush RheumNow ( View Tweet)
COVID: DMARDs, Steroids, a Vaccine - and how long will this continue? Dr. Winthrop reviews all things COVID-related including abstract L01, steroids and DMARDs, vaccination status - and how long this pandemic will last. #ACR20 https://t.co/KWq5ey5Kcf https://t.co/QKFZVnrMpD

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Dr. John Cush RheumNow ( View Tweet)
COVID-19–related mortality rates has become a leading cause of death according to statistics from the Centers for Disease Control and Prevention. Read more here https://t.co/KhrbLce2Q1 https://t.co/fQQ0suzA2A

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Dr. John Cush RheumNow ( View Tweet)
Checkout Dr. Kevin Winthrops RheumNow interview for insights and caveats on the use of COVID-19 vaccination in patients with rheumatic disease and those taking biologics or DMARDs. To hold MTX or not? https://t.co/C1fgCcKgWZ

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Dr. John Cush RheumNow ( View Tweet)

Everyone (Docs and patients) should watch this great video by Dr. Aggarwal from UPitt -he reviews the COVID-19 vaccines, differences, risks and compares to other vaccines https://t.co/j9iqxdgXnL

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Dr. John Cush RheumNow ( View Tweet)

Leading by example at @LLUHPhysicians @LLU_Rheum! We’re all in this together, get vaccinated as soon as you’re able. #COVID #pandemic https://t.co/edPsVUD0nf
Christina Downey, MD, RhMSUS, DipABLM cdowneymd ( View Tweet)
This is the beginning of the END. Please get your COVID vaccine! How cool that the nurse with the needle is my RA patient https://t.co/Hk6ZVCf3WS
Dr. John Cush RheumNow ( View Tweet)
Amer. College OBGYN practice advisory states women who are Pregnant or lactating should be offered COVID-19 vaccines. These vaccines have not been tested in pregnant women & a pregnancy test is not required to receive the vaccine https://t.co/qdbu8mkKWj

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Dr. John Cush RheumNow ( View Tweet)

My Experience as a COVID19 Vaccine Trial Participant by Dr. Kathryn Dao ( @KDAO2011) https://t.co/ILfXLUL8IZ https://t.co/Zd8gsCwnQo

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Dr. John Cush RheumNow ( View Tweet)
ACIP Recommendations for Pfizer Vaccine Candidate by Dr. Rachel Tate ( @uptoTate) https://t.co/l39qH3LuXm https://t.co/9IO3wr13Qm

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Dr. John Cush RheumNow ( View Tweet)
Latest update on the SARS-CoV-2 Vaccine from the ACR. https://t.co/uZ2lmOUigU

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Dr. John Cush RheumNow ( View Tweet)

The RHeumNow Podcast is up! Stop These COVID Mistakes(12.11.20). Loss of life in RA, Predicting Difficult RA, New drugs, COVID vaccine recommendations & what to tell your patients during the pandemic. Watch here>> https://t.co/w1g6ePwYPB or listen here>> https://t.co/Qu39ZLcgkm

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Dr. John Cush RheumNow ( View Tweet)

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